Lediga jobb som Farmakologer och biomedicinare i Göteborg

Do you have an interest in pharmaceutical technology and want to drive drug development projects forward? Would you like to apply your expertise to make an impact in a company that follows the science and turns ideas into life changing medicines? Then AstraZeneca might be the one for you!



AstraZeneca is a global, innovation-driven Biopharmaceutical business that focuses on the discovery, development and commercialisation of prescription medicines for some of the world's most serious diseases. But we're more than one of the world's leading pharmaceutical companies. At AstraZeneca we're dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit.



Pharmaceutical Technology and Development (PT&D) apply science and technology that turns concepts into actual medicines which help millions of people. We work across the entire value chain, designing and delivering active ingredients, formulations and devices required to support new medicines - from supplies for use in toxicology studies and clinical trials to developing the technology to ensure drugs can be scaled up for commercial manufacture.



We are now looking to hire a Formulation Scientist, to strengthen our Oral/Inhaled Formulation & Process Design team. This is an outstanding opportunity for an enthusiastic, innovative and motivated individual who aims to be part of an efficient Global Product Development (GPD) team.



In Global Product Development, a division of PT&D, we focus on the design and development of commercial products and processes. Products in scope are oral solid dosage forms (OSDs), inhaled products (dry powder, metered dose, or nebulization inhalers), and parenteral products, formulated to deliver small and large molecules for diverse therapeutic areas. To meet the future needs of our portfolio the development and strengthening of platform technologies is an important factor, and the use of modelling, simulation, and other digital tools is an essential part of our daily work.


What you'll do

We are looking for a lab based scientist that can balance formulation development and process engineering with a passion for application of digital tools. In this role you will work closely with a team of colleagues in a multi-disciplinary environment to assess, design, develop and deliver high quality clinical and commercial formulations and processes. You can expect to contribute to programs of laboratory scale experiments with line of sight for commercial manufacture by using modelling and simulation approaches as first intent combined with hands-on experimental work as needed.



* Work hands-on to generate data as well as work collaboratively with other experimentalists with different backgrounds to identify/use/drive digital applications as first intent to strategically direct experimentation.
* Be part of cross-functional project teams focusing on developing drug products ranging both early and late-stage development.
* Be a key player to drive and further develop the digital transformation within Formulation & Process Design (FPD).
* Establish strong working relationships with the Modelling & Simulation team members and with other colleagues in Global Product Development to enable an impact-driven application of modelling and simulation tools.
* Manage your own work to achieve drug development and improvement project targets, in a timely fashion and to agreed quality standards, by applying technical knowledge and expertise as well as interpreting results and adapting investigations as appropriate.
* Participate in scientific and/or technology networks to increase base-line knowledge and create awareness of new developments in relevant areas



Essential for the role

* Highly likely to be a PhD or an experienced MSc in chemical engineering, pharmacy or similar subject area
* Strong ability to apply modelling and simulation to deliver value in transferring projects from early to late phase development of pharmaceutical drug products.
* Experience of applying modelling and simulation tools
* A rational approach to problem solving, and an ability to make judgements based on sound reasoning.
* Strong collaborative and communication skills
* Excellent English, both written and spoken.
* Operates confidently and collaboratively within a global organisation, with an integrating mind-set



Desirable for the role

* Experience of pharmaceutical products and process equipment and technology, including product design and methods for experimental characterization and a track record of using multi-variate analysis, chemometrics and AI powered tools.
* Having a knowledge of operational requirements including GMP, Process Safety, Data integrity and Change Control.
* Experience of Drug Product development in the fields of Oral Solid Dosage Forms, Inhaled and Parenteral.
* Experience of continuous processing in a pharmaceutical environment.



Why AstraZeneca?

There's no better place to make a difference to medicine, patients and society. An inclusive culture that champions diversity and collaboration. Always committed to lifelong learning, growth and development.



When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.



We welcome your application (CV and Cover Letter) no later than April 13th, 2026! Visa mindre

Are you ready to translate groundbreaking science into strategic regulatory messaging that drives successful submissions and approvals? We're hiring a Director, Clinical Regulatory Writing, to lead communications strategy and delivery for our Cardiovascular, Renal and Metabolism (CVRM) portfolio.



As the Director of Clinical Regulatory Writing, you'll be at the forefront of driving strategic communication excellence to achieve successful submissions and approvals. Our team provides expert communications leadership to drug projects, crafting clinical-regulatory documents that align with project strategies and regulatory requirements. You'll be engaged in multiple high-priority programs, acting as both a leader and coach, advocating for the team and fostering an environment of productivity and engagement. Your role will involve developing communication strategies, optimize document delivery, and supporting talent growth within CVRM across all phases of clinical development. You will be a visible champion for best practice, innovation, and continuous improvement across the therapy area.

This role is based at AstraZeneca's dynamic R&D site in Gothenburg, where you will join an international, collaborative and cross?functional environment.



Accountability

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Provide expert leadership across a group of submissions or programs, overseeing the communication strategy.
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Lead submission activities and author documents within a program.
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Review key submission documents for consistency of messaging.
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Influence stakeholders at the highest levels of the organization to establish best communications practices.
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Represent Clinical Regulatory Writing on various improvement workstreams and external activities.
*

Drive resourcing strategy within area of accountability.
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Support recruitment and onboarding activities for new members of the group.
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Develop and embed innovative best practices, tools, and processes that elevate quality, speed, and impact.
*

Support talent growth through mentoring and coaching, acting as a role model for the function.



Essential skills/experience

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Bachelor's degree in Life Sciences or related discipline, PhD is strongly preferred.
*

Significant experience in medical/regulatory writing within pharmaceutical/biotech or CRO environments.
*

Proven ability to advise on and lead complex communication programs and submission teams.
*

Strong understanding of drug development and the end?to?end communications process from early development through launch and lifecycle management.
*

In?depth knowledge of relevant technical and regulatory requirements; track record of delivering high?quality, label?focused documents under tight timelines.



Desirable skills/experience

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Advanced scientific degree (e.g., PhD).
*

Experience in using AI tools for medical writing



You'll influence pivotal regulatory outcomes for programs that address some of the world's most prevalent diseases. You'll lead at scale, shape standards, and grow future leaders, while collaborating with world?class cross?functional teams committed to scientific excellence and patient impact.

Ready to lead communications that make a difference? Apply by March 31st, 2026. Visa mindre

The University of Gothenburg tackles society’s challenges with diverse knowledge. 58 000 students and 6800 employees make the university a large and inspiring place to work and study. Strong research and attractive study programmes attract researchers and students from around the world. With new knowledge and new perspectives, the University contributes to a better future.Researcher in immunology

The Institute of Biomedicine is involved in both research and education. In both of these areas, we focus on fundamental knowledge of the living cell – what it consists of, how it works, how its function is directed by the genetic material, and how it interacts with various kinds of micro-organisms. Using this knowledge, we try to elucidate the causes of diseases, and find new ways to diagnose and treat them.

The Institute is composed of the following four departments:


• The Department of Infectious Diseases
• The Department of Microbiology and Immunology
• The Department of Medical Biochemistry and Cell Biology
• The Department of Laboratory Medicine

At present, the institute has about 315 employees and approximately 450 million SEK in total assets

Duties 
Plan and perform advanced immunological experiments investigating reactive oxygen species production in myeloid cells, with a particular focus on microglia.

Qualifications 
PhD in a relevant subject, such as medicine, biomedicine, or molecular biology. Documented experience in immunological research, animal experimentation, and multicolor flow cytometry is required. Experience with studies on microglia, iPSC models, and neurodegenerative mouse models is considered a strong merit.

Employment 
The position is a fixed-term employment for 6 months, based at the Institute of Biomedicine. Starting date as agreed upon.

Contact information for the post 
If you have any questions about the position, please contact professor Anna Martner, phone: +46736-517644, mail: [email protected]

Unions 
Union representatives at the University of Gothenburg can be found here:?https://www.gu.se/om-universitetet/jobba-hos-oss/hjalp-for-sokande 

Application 
To apply for a position at the University of Gothenburg, you have to create an account in our recruitment system. Submit your application via the University of Gothenburg’s recruitment portal by clicking the “Apply” button. It is your responsibility to ensure that the application is complete as per the vacancy notice, and that the University receives it by the final application deadline. 

The application should contain proof of completed PhD.

Applications must be received by: 2026-04-07

The University works actively to achieve a working environment with equal conditions, and values the qualities that diversity brings to its operations.

Salaries are set individually at the University.

In accordance with the National Archives of Sweden’s regulations, the University must archive application documents for two years after the appointment is filled. If you request that your documents are returned, they will be returned to you once the two years have passed. Otherwise, they will be destroyed.

In connection to this recruitment, we have already decided which recruitment channels we should use. We therefore decline further contact with vendors, recruitment and staffing companies. Visa mindre

Do you have knowledge in pharmaceutical formulation development, with a practical understanding of design of experiments (DOE), material properties, and data curation and processing? Would you like to apply your expertise to link materials properties to process performance in continuous manufacturing? Then AstraZeneca might be the place for you.

AstraZeneca is a global, innovation driven biopharmaceutical business that focuses on the discovery, development and commercialisation of prescription medicines for some of the world’s most serious diseases. We are currently seeking a consultant Formulation Scientist to join our team within Global Product Development (GPD), part of Pharmaceutical Technology & Development (PT&D), in Gothenburg, Sweden.

You bring fundamental scientific understanding of formulation science and hands on laboratory experience, with the ability to work independently and contribute in cross functional development settings.

In PT&D, we are the bridge between science and innovative medicines that help millions of people. We design and deliver active ingredients, formulations and devices required to support new medicines—from supplies for use in early toxicology studies and clinical trials to developing technology to enable scale up for commercial manufacture. At GPD we focus on oral, inhaled, and parenteral drug products, playing a key role in the development of new medicinal products.

Reponsibilities
What you’ll do:

We are looking for lab-based scientists for work within our functions Formulation Product Development and Process Technology and Engineering. The roles will have different focus depending on academic background/professional experience, either pharmaceutical development or process control and engineering. In this role you will work closely with a team of colleagues in a multi-skilled environment to design, develop and deliver high quality clinical and commercial formulations and processes.

You can expect to contribute to programs of laboratory scale experiments with line of sight for commercial manufacture by using modelling and simulation approaches as first intent. We expect that you, just like us within Global Product Development, have a passion for application of digital tools.

• Work hands-on in the laboratories (small and large scale) to generate drug product for further characterization and confirmation of predictions
• Work collaboratively with colleagues with different backgrounds to identify/use/drive digital applications to strategically direct development
• Be part of cross-functional teams delivering drug projects, including contributions to regulatory documentation and submissions, applying your understanding of drug development and relevant requirements from medical authorities
• Take part in tech transfer of manufacturing methods to other sites (within and/or outside AZ) and give consultation to internal and external parties
• Be a key player to drive and further develop the digital transformation within Global Product Development.
• Establish strong working relationships with the modelling & simulation team and with other colleagues to enable an impact-driven application of modelling and simulation tools
• Manage your own work to achieve drug development and improvement project targets, in a timely fashion and to agreed quality standards, by applying technical knowledge and expertise as well as interpreting results.
• Participate in scientific and/or technology networks to increase base-line knowledge and create awareness of new developments in relevant areas

Your profile
Essential for the role
• MSc in engineering, pharmacy or similar discipline
• Early adapter of digital solutions and AI tools
• Excellent English, both written and spoken
• Operates confidently and collaboratively within a global organisation, with an integrating mind-set
• Strong collaborative and communication skills

Desirable for the role:

• Previous experience of working in a lab environment
• Experience of pharmaceutical products and process equipment and technology, including product design and methods for experimental characterization
• Having a knowledge of operational requirements including GMP, Process Safety, Data integrity and Change Control
• Experience of continuous processing in a pharmaceutical environment, and monitoring of continuous processes
• Experience of applying modelling and simulation tools
• Experience in developing and utilising digital solutions and AI-driven software to facilitate and accelerate project work


About the Organisation
This is a consultant assignment at AstraZeneca in Göteborg for 6 month, starting in May 2026.
During the time you will be hired by QRIOS.
Please apply by registering your CV here on our website. Click on the "Ansök" button to the right. It is our recommendation that you register as much information as possible and that you attach a complete CV-document. Please check that your correct e-mail address is registered. Visa mindre

Our Genome Engineering Team in Gothenburg, Sweden focuses on developing treatment for Rare Diseases. We continually push the boundaries of science to expand the limits of scientific research to better understand rare diseases, discover new life-changing treatments and deliver medicines to patients.

As a Senior Research Scientist, you will be a key member of the Genome Engineering Department. You will join our international team that develops novel genome engineering technologies and applies these breakthroughs to generate innovative gene therapies. We provide a stimulating environment with state-of-the-art facilities where you can transform cutting-edge genome engineering tools into effective and safe medicines.

About the position
In this laboratory-based role, you will leverage your scientific expertise in genome engineering and innovative thinking to develop novel tools and applications that can lead to breakthrough therapies. As a key member of cross-functional project teams, you will develop and evaluate genome editing strategies for specific disease projects. Accountabilities will include innovative optimization of genome engineering technologies to facilitate effective gene editing in target cell & tissue types, developing relevant assays, analyzing gene editing outcomes, documenting, interpreting, and communicating results to appropriate partners.

Reponsibilities
• Establishing and maintaining disease cell models using immortalized or iPSC cell lines
• Establishing and running cellular and biochemical assays to evaluate efficacy of therapeutic genome editing approaches in disease models
• Documenting, interpreting and communicating results to stakeholders and partners

Your profile
Essential for the role:
• PhD degree in molecular cell biology or relevant areas with strong wet-lab skills, or MSc degree with equivalent experience
• Experience with handling and differentiating iPSCs to different cell types (e.g. liver, heart)
• Track record of establishing high-quality cellular assays (e.g. viability, metabolic activity, protein quantification, flow cytometry, microscopy)
• Strong communication skills, scientific rigor and ethics, ability to effectively work independently and collaboratively in a team

Desirable for the role:?
• Experience in metabolism research
• Understanding and previous hands-on experience with CRISPR-Cas9 technologies
• Hands-on experience with standard molecular biology approaches for quantifying protein levels (e.g. Western blot, ELISA) or measuring protein activity
• Experience working with lentiviral vectors for engineering cell models

About the Organisation
This is a consultant assignment at AstraZeneca in Göteborg for 1 year, starting mid of April 2026.
During the time you will be hired by QRIOS.
Please apply by registering your CV here on our website. Click on the "Ansök" button to the right. It is our recommendation that you register as much information as possible and that you attach a complete CV-document. Please check that your correct e-mail address is registered. Visa mindre

Are you energized by building high performing partnerships and driving operational excellence at scale? Do you have a strong track record in alliance management within outsourced service models in pharma R&D? We're recruiting a Director, Alliance Management to serve as Alliance Lead for one or more strategic partnerships with Contract Research Organizations (CROs), ensuring partners meet customer needs, deliver to contract, and that governance, communication, and relationship health are best-in-class,

This position is based at our Gothenburg site, a world-class R&D hub where cross functional teams, from clinical operations and data science to regulatory and quality, work together to advance innovative medicines. In this role, you will collaborate across regions and time zones, engaging global stakeholders and supplier leadership to align on strategy, governance, and continuous improvement, while leveraging Gothenburg's R&D hub's vibrant ecosystem and facilities, as well connections with AstraZeneca's cross-functional teams.



Accountabilities:

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Supplier/Model Governance: Lead alliance management for assigned suppliers and service lines; own operational governance, risk identification/escalation, and resolution; support audits; and contribute to executive and model-level forums.
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Quality and Performance: Define and monitor metrics/service level agreements (SLAs); ensure delivery to contract; maintain strong internal/external relationships; provide performance visibility; embed lessons learned; and drive continuous improvement.
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Study Team Support: Clarify roles and responsibilities across delivery teams and ensure effective interface processes and ways of working with suppliers.
*

Alliance Management Development: Coach more junior team members; act as delegate for the AM/CRO Group Lead; and lead or support critical initiatives within and beyond Alliance Management.



Essential Requirements:

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University degree in a relevant field (or equivalent experience)
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Substantial experience in the pharmaceutical industry or a clinical research organization
*

Detailed knowledge of clinical and pharmaceutical drug development across phases
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Proven experience managing external partners and strategic supplier relationships
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Experience directing alliance governance frameworks and performance metrics
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Strong leadership and influencing skills (including leading without formal authority)
*

Effective collaboration across global and functional boundaries
*

Excellent conflict resolution, mediation, and negotiation skills
*

Demonstrated agility in complex problem solving with multiple stakeholders
*

Familiarity with GCP and related guidelines



At AstraZeneca, partnerships power our progress. You'll impact alliances that accelerate science and deliver to a patient-focused environment. Ready to make your mark? Apply now and help us redefine how we partner to transform healthcare. We welcome your application by 24 February 2026. Visa mindre

Are you passionate about transforming science into clear and compelling regulatory documents that drive successful drug development? We are seeking a talented and experienced Associate Director, Clinical Regulatory Writing to join our CVRM (Cardiovascular, Renal and Metabolism) Clinical Regulatory Writing team in Gothenburg, Sweden. With more than 2,400 employees from over 50 countries, our vibrant Gothenburg site is a truly inspiring place to work - where the history and future of scientific breakthroughs come together. We believe that the diversity of our people is crucial to bringing new discoveries to life.



Accountabilities:

The CVRM Clinical Regulatory Writing group provides expert strategic leadership and communications expertise to clinical drug programs, ensuring delivery of high-quality, label-focused documents aligned with project strategy, regulatory requirements, and communications best practices. Role holders not only author critical clinical-regulatory documents but also act as critical reviewers to achieve the highest quality standards. Team members also represent the Clinical Regulatory Writing skill set on both drug and non-drug projects, advocating for best practices and continuous improvement.



Key Responsibilities

As an Associate Director, Clinical Regulatory Writing, you will:

*

Provide strategic leadership and communication expertise to clinical drug programs across the CVRM portfolio.
*

Author and critically review clinical-regulatory documents, ensuring the highest regulatory, technical, and quality standards.
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Represent Clinical Regulatory Writing on project teams, advocating for communication best practices.
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Provide strategic communications leadership within clinical delivery or submission teams, establishing standards and promoting quality and efficiency.
*

Act as NDA/MAA submission lead, driving the development of the clinical Submission Communication Strategy (cSCS) and successful submission delivery.
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Lead both internal and external authoring teams and cultivate strong partnerships with vendor medical writers to ensure timely, high-quality document delivery.
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Translate complex clinical data into clear, concise, and accurate messages tailored to specific audiences.
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Support the development and upskilling of colleagues within the Clinical Regulatory Writing function.
*

Champion continuous improvement and operational excellence in communications.



Essential Skills/Experience:

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Bachelor's degree in Life Sciences or a related discipline.
*

Significant medical writing experience within the pharmaceutical industry or a Contract Research Organization (CRO).
*

Proven ability to advise and lead communications projects and teams.
*

Strong understanding of drug development and the communications process from early development through to launch and lifecycle management.
*

In-depth knowledge of technical and regulatory requirements relevant to clinical regulatory writing.



Desirable Skills/Experience:

*

Advanced degree in scientific discipline (e.g., Ph.D.).



If you are driven to deliver impactful regulatory communications, excel in multidisciplinary teams, and want to shape the future of clinical development, we encourage you to apply.

Apply with your CV and cover letter by 10 March, 2026! Visa mindre

Are you ready to make a meaningful impact on patients' lives through the work you do? We are seeking an Associate Director for our Global Portfolio and Project Management Organization (GPPM). This role is pivotal in advancing our pipeline and delivering Growth Through Innovation by partnering closely with Research & Development (R&D) and business leaders. As the Associate Director of Global Project Management (GPM), you will lead global, cross-functional drug development teams and sub?teams to deliver against strategic objectives and secure significant development, regulatory, and commercial outcomes. Complementing the Global Project Leader, you will provide top?level oversight and integration from development through to commercialization.

This position is based at our Gothenburg site, a vibrant nexus of innovation where more than 2,400 colleagues from 50+ countries collaborate across state?of?the?art laboratories and shared spaces to accelerate decision?making and problem?solving.

Accountabilities

Strategic business partnership

* Provide input into project strategy and vision through expertise in project management and navigation of therapy area and corporate governance processes.
* Ensure alignment of project and operational deliverables with team strategy; share lessons learned and communicate them where relevant.
* Manage or lead elements of the development plan or strategy as delegated by the Global Project Leader.
* Ensure appropriate linkages between project strategy and key internal processes and maintain relevant enterprise systems.
* Collaborate with alliance partners where applicable and partner with Business Development to provide project input to potential deal cases.

Cross?functional team leadership and delivery

* Lead cross?functional drug development teams and sub?teams, ensuring accurate, achievable, and scenario?based project plans.
* Act as a core GPT member, driving effective operation of early and/or late?stage GPTs, including overall plans, priorities, budget, and risk management.
* Build and sustain a cohesive, high?performing team with the Global Project Leader; facilitate decision?making and issue resolution.
* Establish and manage effective team communication processes and proactively ensure robust information management practices.

Governance and investment decisions

* Guide GPTs toward effective governance interactions and lead the development of high?quality investment decision documentation.
* Integrate and synthesize information for teams and senior management/governance bodies to enable efficient decision?making.

Planning, monitoring, and delivery

* Ensure GPT deliverables, budgets, schedules, and performance standards are realistically set, governance?approved, and achieved.
* Maintain plans with the highest data quality and be accountable for all project management deliverables for GPTs and sub?teams.

Entrepreneurship

* Identify and drive opportunities for positive change and barrier removal within and beyond the team.
* Champion company standard processes and apply business knowledge to drive cross?functional and cross?project learning.

Essential skills and experience

* Bachelor's degree with 5+ years' experience supporting cross?functional drug development teams or leading sub?teams.
* Project management experience with a successful track record delivering within agreed time, quality, and cost.
* Proficiency with project management tools and processes.
* Demonstrated ability to lead high?performing teams and establish effective team operations.
* Ability to work effectively with senior collaborators.
* Strong information management skills, including modern collaboration tools (e.g., SharePoint, Microsoft Teams, OneNote).
* Experience ensuring high?quality data in enterprise systems.

Desirable skills and experience

* Advanced degree in a scientific field and/or MBA.
* 7+ years' relevant experience.
* In?depth knowledge of the drug development process, with therapeutic area?specific experience.
* Experience with advanced project management tools (e.g., Planisware/PLANIT).
* Project Management Professional (PMP) certification.

We value the connectivity and pace that in?person collaboration enables. Our hybrid model typically includes a minimum of three days per week on site, with flexibility built in to support individual needs and team delivery.



Why AstraZeneca
At AstraZeneca, we are on a mission to do more and be more. Join us at an exciting time of growth through innovation. We are reimagining how we work, introducing new solutions and technology through investment in automated processes. By driving greater consistency and efficiency, we accelerate our next chapter of growth. Here, every person plays a part in our story. Speak up, take initiative, and make it yours.



Ready to make this role yours? Submit your cover letter and CV by 17th of February. Visa mindre

Join the Bioscience Immunology team within Research and Early Development, Respiratory & Immunology. You will support in vitro studies, and ex vivo analyses on mouse cells, focusing on inflammatory and autoimmune diseases. Respiratory & Immunology is one of AstraZeneca’s core therapy areas, aiming to understand, treat, modify, and ultimately cure respiratory and autoimmune diseases.

Reponsibilities
• Plan and execute experiments: Design, perform, and analyze in vitro and ex vivo studies to advance drug discovery projects and generate publishable insights.
• Contribute scientifically: Engage in study design discussions and data interpretation; present findings, rationale, and recommendations.
Accountability:
• Hands-on work: Conduct in vitro and ex vivo analyses from rodent studies alongside a team of committed scientists.
• Data responsibility: Uphold the highest standards of data integrity, quality control, and archiving.
• Communication: Evaluate and interpret primary data; write reports and summaries; present in team and project meetings.

Your profile
Essential for the role:

• Master’s in biology or related field
• Flow cytometry expertise: At least 5 years’ experience with routine FACS on mouse samples, including organ processing/digestion, staining, antibody panel design; proficiency with BD FACSDiva instruments and FlowJo.
• Cellular/molecular techniques: Ability to independently plan, execute, and analyze protein expression/activation assays (ELISA, Western blot, Meso Scale Discovery) and RNA analysis (extraction, qRT PCR).
• Data and statistics: Understanding of statistical methods, quality control, reporting, and data archiving.
• Communication: Excellent written and spoken English; strong presentation skills.

Desirable for the role:

• PhD in immunology; deep understanding of autoimmune diseases, especially gut, skin, or joint immunology.
• In vivo experience: Familiarity with animal models of inflammation/autoimmunity.
• Cell isolation and sorting: Experience with column-based cell isolation (e.g., MACS, StemCell Technologies) and FACS-mediated cell sorting.
• Cell culture: Experience with murine leukocytes in vitro assays.

About the Organisation
This is a consultant assignment at AstraZeneca in Göteborg from March until October 2026. During the time you will be hired by QRIOS.
Please apply by registering your CV here on our website. Click on the "Ansök" button to the right. It is our recommendation that you register as much information as possible and that you attach a complete CV-document. Please check that your correct e-mail address is registered. Visa mindre

Our Genome Engineering Team in Gothenburg, Sweden focuses on developing treatment for Rare Diseases. We continually push the boundaries of science to expand the limits of scientific research to better understand rare diseases, discover new life-changing treatments and deliver medicines to patients.

As a Senior Research Scientist, you will be a key member of the Genome Engineering Department. You will join our international team that develops novel genome engineering technologies and applies these breakthroughs to generate innovative gene therapies. We provide a stimulating environment with state-of-the-art facilities where you can transform cutting-edge genome engineering tools into effective and safe medicines.

About the position
In this laboratory-based role, you will leverage your scientific expertise in genome engineering and innovative thinking to develop novel tools and applications that can lead to breakthrough therapies. As a key member of cross-functional project teams, you will develop and evaluate genome editing strategies for specific disease projects.

Accountabilities will include innovative optimization of genome engineering technologies to facilitate effective gene editing in target cell & tissue types, developing relevant assays, analysing gene editing outcomes, documenting, interpreting, and communicating results to appropriate partners.

Reponsibilities
• Designing and evaluating therapeutic genome editing strategies for specific disease indications
• Optimization of genome engineering technologies to facilitate effective gene editing in target cell & tissue types
• Developing and routinely running appropriate assays for evaluating gene editing outcomes
• Documenting, interpreting and communicating results to stakeholders and partners

Your profile
Essential for the role:?
• PhD degree in life sciences or relevant areas with strong wet-lab skills, or MSc degree with equivalent experience
• Strong skills in working with mammalian cell models (immortalized or primary)
• Understanding and previous hands-on experience with CRISPR-Cas9 technologies
• Strong skillset in standard molecular biology techniques in analyzing DNA, RNA and protein (e.g. PCR, sequencing technologies, RNA extraction, qPCR, Western blot, ELISA)
• Strong communication skills, scientific rigor and ethics, ability to effectively work independently and collaboratively in a team

Desirable for the role:?
• Experience working with lentiviral vector for engineering cell models
• Experience with using liquid handling instruments
• Experience with optimizing genome editing technologies (construct design, gRNA optimization, delivery) or equivalent protein engineering expertise

About the Organisation
This is a consultant assignment at AstraZeneca in Göteborg from April until end of March 2027. During the time you will be hired by QRIOS.
Please apply by registering your CV here on our website. Click on the "Ansök" button to the right. It is our recommendation that you register as much information as possible and that you attach a complete CV-document. Please check that your correct e-mail address is registered. Visa mindre

Göteborgs universitet möter samhällets utmaningar med mångsidig kunskap. 58 000 studenter och 6800 medarbetare gör universitetet till en stor och inspirerande arbetsplats. Stark forskning och attraktiva utbildningar lockar forskare och studenter från hela världen. Med ny kunskap och nya perspektiv bidrar Göteborgs universitet till en bättre framtid.Institutionen för kliniska vetenskaper är en av sex institutioner vid Sahlgrenska akademin vid Göteborgs universitet. Vid institutionen bedrivs forskning och utbildning som sätter människans hälsa och livskvalitet i fokus. Vi representerar 16 olika ämnesområden och är indelade i fyra sektioner.

Institutionen för kliniska vetenskaper, söker nu en postdoktor, med placering vid avdelningen för gynekologi och obstetrik. Avdelningen för gynekologi och obstetrik bedriver forskning om reproduktiv hälsa och graviditetsutfall. Många av forskargruppsledarna har en translationell approach med laborativ forskning knuten till klinisk forskning. Forskningen för anställningen bedrivs på laboratoriet för neurofysiologi på Sahlgrenska akademin. 

Anställningen är knuten till ett forskningsprojekt som leds av Lina Bergman. Forskargruppen fokuserar på preeklampsi med dess komplikationer för mor och barn på kort och lång sikt. Särskilt forskningsintresse finns inom cerebrala komplikationer hos modern. Forskningen innefattar biobanker och databaser i Sverige och Sydafrika, epidemiologiska studier, randomiserade kontrollerade prövningar av läkemedel mot preeklampsi, in vitrostudier av blod-hjärnbarriärskada samt immunologisk reaktivitet i hjärnan samt en djurmodell av preeklampsi. Anställningen kommer att vara lokaliserad till laboratoriet för neurofysiologi på Sahlgrenska akademin där Lina Bergmans grupp bedriver den prekliniska forskningen.

Lina Bergmans forskargrupp tillhör också Wallenbergcentrum för molekylär och translationell medicin (https://www.gu.se/en/molecular-translational-medicine), vilket medför goda möjligheter för karriärutveckling och nätverksbyggande.

 

Ämne 
Neuroprotektiv behandling vid preeklampsi och eklampsi med fokus på effekter postpartum

 

Ämnesbeskrivning 
Forskningen syftar till att bättre förstå mekanismer som ligger bakom preeklampsi och eklampsi, neurologiska komplikationer till sjukdomen och undersöka potentiella neuroprotektiva behandlingar vid preeklampsioch eklampsi med fokus på uppföljning efter graviditeten.  Forskningen kommer att bedrivas genom djurmodeller (råttor och möss), framförallt s.k RUPP modellen, där blodflödet reduceras till livmodern och därmed framkallar en klinisk bild som liknar preeklampsi med hypertension och organpåverkan. Modellen håller även på att utvecklas för att spegla kramper, eklampsi samt utvärdering av hjärnskador postpartum. Målet med modellen är att behandla med gamla och nya läkemedel med förmodad neuroprotektiv effekt och utvärdera effekten genom bedömning av blod-hjärnbarriärens integritet, grad av neuroinflammation och kärlreaktivitet. Vi planerar även att undersöka minnesförmågan hos djur efter avslutad behandling som en proxy för långtidsutfall.

 

Arbetsuppgifter 
Arbetsuppgifterna innebär att utföra djurkirurgi som beskriven ovan, handha djur före och efter kirurgi samt tillvarata biologiska prover efter avslutade experiment. Vidare innebär tjänsten att medverka i utvärderingen av utfallen enligt ovan med de tekniker som finns vid laboratoriet sedan tidigare. Arbetsuppgifterna innebär även att medverka i handledning av doktorander vid laboratoriet samt studenter som vistas på laboratoriet. Specifikt för denna postdoc-position ingår att utveckla utvärdering av effekter på hjärnan efter förlossningen där minne, exekutiva förmågor och hjärnskada utvärderas vid olika tidpunkter i djurmodeller. Slutligen innebär arbetsuppgifterna att sammanställa resultat och medverka i skrivandet av publikationer.

 

Behörighet 
Behörig att anställas som postdoktor är den som har avlagt doktorsexamen, konstnärlig doktorsexamen eller som har en utländsk examen som bedöms motsvara doktorsexamen. Detta behörighetskrav ska vara uppfyllt senast vid tidpunkten då anställningsbeslutet fattas.

I första hand bör den komma i fråga som har avlagt examen högst tre år före ansökningstidens utgång. Även den som avlagt examen tidigare bör komma i fråga i första hand, om det finns särskilda skäl. Med särskilda skäl avses ledighet på grund av sjukdom, föräldraledighet, förtroendeuppdrag inom fackliga organisationer, tjänstgöring inom totalförsvaret, eller andra liknande omständigheter samt klinisk tjänstgöring eller för ämnesområdet relevant tjänstgöring/uppdrag. 

  

Bedömningsgrunder 
Sökande ska ha en doktorsexamen i ett ämne som är relevant för anställningen. För anställningen krävs dokumenterad vana vid djurhantering och godkänd kurs i hantering av djur i forskning samt tidigare erfarenhet av praktisk laborativt arbete. Utmärkta kunskaper i engelska, både skriftligt och verbalt, är nödvändigt. Kunskap i svenska är meriterande.

Meriterande är vana vid RUPP-kirurgi, blodflödesundersökning, in vivo exprimentering och vana av tester av minne och exekutiv förmåga i rått-modeller. För anställningen är även kunskaper i neuroanatomi och/eller neurofysiologi meriterande.

Den sökande förväntas planera, utföra och analysera experimenten på ett självständigt sätt och aktivt bidra vetenskapligt till gruppen. Hänsyn kommer tas till, eget driv, organisatorisk förmåga, noggrannhet och självständighet. Vi lägger stor vikt vid personlig lämplighet.

För mer information och för att söka anställningen, se annonsen i sin helhet på https://www.gu.se/om-universitetet/jobba-hos-oss/lediga-anstallningar 

Universitetet arbetar aktivt för en arbetsmiljö med jämställda förhållanden och sätter värde på de kvalitéer mångfald tillför verksamheten.

Universitetet tillämpar individuell lönesättning.

Enligt Riksarkivets föreskrifter är universitetet skyldigt att förvara ansökningshandlingar i två år efter tillsättningsbeslutet. Om du som sökande till en anställning särskilt begär tillbaka dina handlingar återsänds de när de två åren har förflutit, i annat fall kommer de att gallras ut.

Till bemannings- och rekryteringsföretag och till dig som är försäljare: Göteborgs universitet anlitar upphandlad annonsbyrå i samband med rekrytering av personal. Vi undanber oss vänligen men bestämt direktkontakt med bemannings- och rekryteringsföretag samt försäljare av jobbannonser. Visa mindre

Göteborgs universitet möter samhällets utmaningar med mångsidig kunskap. 58 000 studenter och 6800 medarbetare gör universitetet till en stor och inspirerande arbetsplats. Stark forskning och attraktiva utbildningar lockar forskare och studenter från hela världen. Med ny kunskap och nya perspektiv bidrar Göteborgs universitet till en bättre framtid.Vid Institutionen för neurovetenskap och fysiologi vid Sahlgrenska akademin bedrivs omfattande forskning och undervisning över stora kunskapsområden - från molekyl till människa. Verksamheten utgörs av fem sektioner; farmakologi, fysiologi, hälsa och rehabilitering, klinisk neurovetenskap samt psykiatri och neurokemi.

Institutionen för neurovetenskap och fysiologi söker nu en biträdande forskare med placering vid Sektionen för farmakologi.

Målet med anställningen är att utveckla GRAB-fotometri för att mäta neurotransmittorer som acetylkolin och dopamin i realtid under komplexa beteenden hos försöksdjur.

Arbetsuppgifter

Som biträdande forskare kommer du att delta i ett projekt som syftar till att etablera GRAB-fotometri, både ex vivo och in vivo.

Du kommer att ansvara för inköp av utrustning och material som krävs för att sätta upp ett komplett system, samt inkorporera utrustningen med befintliga tekniker som i dagsläget används i labbet. När GRAB-fotometri etablerats förväntas du kunna arbeta självständigt och genomföra försök på egen hand. Du förväntas också kunna hantera försöksdjur och utföra enklare beteendestudier.

I arbetsuppgifterna ingår även att analysera och sammanställa data för publicering i vetenskapliga tidskrifter. Dessa analyser kommer förutom GRAB-fotometri att inkludera data som erhållits genom elektrofysiologiska mätningar.

Kvalifikationer

För denna anställning ska du ha minst en masterexamen inom medicin eller naturvetenskap med inriktning mot farmakologi eller neurovetenskap. Du ska ha tidigare erfarenhet av fotometri eller liknande tekniker. Du ska även ha erfarenhet av praktiskt djurexperimentellt arbete. God kännedom om neurofysiologi och neurotransmission är ett krav för tjänsten.

Det är meriterande om du har dokumenterad erfarenhet av neurofysiologiska studier, särskilt elektrofysiologi, då detta är en av de huvudtekniker som kommer att användas i projektet.

Du ska kunna kommunicera obehindrat på engelska, både muntligt och skriftligt, samt ha förmåga att arbeta både självständigt och i grupp. Vi lägger stor vikt vid personlig lämplighet.

Anställning

Anställningen är en tidsbegränsad anställning i 9 månader, 100% av heltid, med placering tills vidare vid Institutionen för neurovetenskap och fysiologi. Tillträde: snarast eller enligt överenskommelse. 

Kontaktuppgifter för anställningen

Har du frågor om anställningen är du välkommen att kontakta universitetslektor Louise Adermark, tfn: +46 31 786 39 75, e-post: [email protected]

Ansvarig chef är professor/sektionschef Michael Winder, tfn: +46 31 786 34 77, e-post: [email protected]

Ansökningshandlingar skickas inte till kontaktpersonerna.

Fackliga organisationer

Fackliga företrädare vid Göteborgs universitet hittar du här: https://www.gu.se/om-universitetet/jobba-hos-oss/hjalp-for-sokande

Ansökan

Du söker anställningen via Göteborgs universitets rekryteringsportal genom att registrera din ansökan elektroniskt via hemsidan: https://www.gu.se/om-universitetet/jobba-hos-oss/lediga-anstallningar

Du som sökande ansvarar för att ansökan är komplett i enlighet med annonsen och att den är universitetet tillhanda senast sista ansökningsdag.

Ansökan ska vara inkommen senast: 2026-02-04

Universitetet arbetar aktivt för en arbetsmiljö med jämställda förhållanden och sätter värde på de kvalitéer mångfald tillför verksamheten.

Universitetet tillämpar individuell lönesättning.

Enligt Riksarkivets föreskrifter är universitetet skyldigt att förvara ansökningshandlingar i två år efter tillsättningsbeslutet. Om du som sökande till en anställning särskilt begär tillbaka dina handlingar återsänds de när de två åren har förflutit, i annat fall kommer de att gallras ut.

Till bemannings- och rekryteringsföretag och till dig som är försäljare: Göteborgs universitet anlitar upphandlad annonsbyrå i samband med rekrytering av personal. Vi undanber oss vänligen men bestämt direktkontakt med bemannings- och rekryteringsföretag samt försäljare av jobbannonser. Visa mindre

Are you a passionate scientist, eager to join a company at the forefront of sample management technologies? Would you like to contribute to the continuous improvement of life-changing projects? Perfect, we have a new challenge for you!

We are looking for a motivated and engaged team member for our Compound Management team at our vibrant R&D site at AstraZeneca in Gothenburg, Sweden.

In this role you will be responsible for the storage and timely supply of compounds to AstraZeneca's drug discovery projects. Highly automated liquid handling systems will be employed to supply molecules to AstraZeneca scientists and partner organisations. You will be a part of the Discovery Sciences organisation, operating within a first-class scientific environment to support drug discovery across each of AstraZeneca's Therapeutic Areas.

Thrive in a place where the brightest and most curious minds seamlessly come together in our inclusive environment.

What you will do:

In this position, you will get the opportunity to work in a dynamic and enthusiastic environment, whilst delivering critical support to all phases of drug discovery projects and working with a broad range of chemical modalities. You will be supporting projects by processing and providing compounds in the requested format - assay ready plates, serially diluted mother plates, formulations and solids. Bringing in new capabilities and building new workflows are core activities within our group, performed in a cross-functional collaboration setting with the drug discovery projects.

You are expected to act upon day-to-day issues that occur whilst processing samples and run Compound Management development projects to ensure continuous improvement within the local team and the global department.



Examples of typical tasks:

*

Designing, performing and interpreting experiments independently to investigate process improvements and evaluate new technologies.

*

Working closely with internal project teams to meet drug discovery needs.

*

Rapidly addressing collaborator queries with regards to Compound Management orders, software, processes and capabilities.

*

Achieving personal scientific visibility through project contributions, internal presentations and publications.



We work collaboratively within our Compound Management team to understand the collaborator needs and how to add value through our experience and capabilities. To maintain this position and provide support within agreed service levels, we actively seek ways to improve our process, build cross team workflows and exploit new technologies.



Essential requirements for the role:

Compound Management is a highly collaborative group, working to tight delivery schedules - so the ability to be comfortable working at a fast, goal-oriented pace, with a team-focused attitude, is essential to being successful in the role. Furthermore, you have excellent communication skills with a proactive delivery and collaborator focus.



We also believe that you have:

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A BSc/MSc in Chemistry/Biotechnology/Chemical engineering, with relevant experience.

*

Excellent communication skills and high work ethics.

*

Excellent problem-solving skills and ability to identify and implement improvement activities.

*

A track record in the performance of a range of practical skills, including non-routine complex tasks, to a high level.



We believe that our new colleague shares our passion for science, technology and innovation and understands the drug discovery process. Previous experience of working in a compound management role and operating integrated automation equipment like liquid handlers and scheduling software is a strong merit. Some experience with IT (/Python/Java coding) is an advantage but not a requirement.



Why AstraZeneca?
Here we are committed to making a difference. We have built our business around our passion for science. Now we are fusing data and technology with the latest scientific innovations to

achieve the next wave of breakthroughs.

So, what's next?

If you're passionate about the possibilities of science to make a difference, welcome to join us! We look forward to getting to know you and invite you to submit your application as soon as possible but no later than the February 1, 2026. Applications will be reviewed continuously.

For more information about the position please contact recruiting manager Karin Kaspersson, Director Compound Management at [email protected]. Visa mindre

Full-time consultancy assignment via Poolia- Mölndal, Gothenburg

Poolia is now looking for a Senior Research Scientist for an exciting full-time consultancy assignment at a leading global pharmaceutical company based in Mölndal, Gothenburg. This is a unique opportunity to work at the forefront of genome editing, AI-driven protein design and precision medicine, contributing to research that can lead to life-changing therapies.

About the position
You will join a highly specialized Genome Editing Technologies team focused on genome medicine programs for rare diseases. The work is carried out in an international, cross-functional research environment with access to state-of-the-art facilities and advanced technology platforms.

The team develops novel genome engineering and targeted delivery technologies, applying cutting-edge protein design and AI-generated binders to enable next-generation cell and gene therapies.

• Assignment period: April 4, 2026 – April 3, 2027
• Scope: Full-time

This is a consultancy assignment via Poolia, where you will be employed by Poolia and work on-site at our client’s R&D facilities in Mölndal.

Reponsibilities
As a Senior Research Scientist, you will combine in silico and wet-lab expertise and contribute with strong scientific leadership and innovative thinking. You will work independently while collaborating closely with multidisciplinary project teams.

Key Responsibilities
• Design, test and optimize AI-designed protein binders for targeted delivery and modulation of intracellular protein activity
• Plan and execute experiments aligned with project objectives within targeted delivery
• Design, develop and optimize biochemical, molecular and cell-based assays
• Analyze, document, interpret and communicate experimental results to relevant stakeholders
• Provide scientific guidance and mentorship to junior colleagues

Your profile
Required Qualifications
• PhD in molecular or cell biology, genetics, biochemistry or a related field
• Minimum of 2 years’ experience from the pharmaceutical or biotechnology industry
• Strong expertise in molecular biology (construct design, in vitro experimentation, assay development)
• Hands-on experience in data analysis using R, Python and/or Linux
• Ability to work independently, structured and collaboratively in a team environment
• Strong communication skills and high scientific integrity

Desirable Experience
• Experience with large-scale experimentation (screening, HTS) and laboratory automation
• Experience in protein engineering using rational or AI-driven approaches
• Experience applying AI to accelerate research workflows
• Expertise in advanced genome editing technologies (e.g. prime editing, knock-in)
• Track record of innovation demonstrated through publications and/or patents

About the Organisation
As a consultant with us, you will have a dedicated consultant manager who supports you throughout the assignment. We want you to feel well and enjoy your work, which is why we offer discounts at various fitness facilities as well as regular social activities. Naturally, your employment with Poolia is covered by a collective bargaining agreement and includes insurance, occupational pension and occupational health services. Visa mindre

Join a global, science-led company where your work in regulatory process excellence enables faster, compliant access to medicines for patients worldwide!

We are looking for someone that would like to join our Regulatory Process team as Director within Regulatory Process.

This is an opportunity to work at the intersection of process, data, and technology-partnering across groups and systems to modernise how we operate and drive continuous improvement.You will be able to collaborate with internal stakeholders across regions and functions, opportunity to engage with health authority industry group and vendor initiatives, to shape best-in-class regulatory practices.

At AstraZeneca, every one of us plays a part in bringing life-changing medicines to patients. We are driven by science, united by our purpose, and motivated by the opportunity to make a meaningful difference for people, society, and the planet. We foster an inclusive, innovative environment where you can thrive-growing your career while shaping the future of health. If you are passionate about transforming how global regulatory processes deliver patient impact, this is the place to do it.

As a Director Regulatory Process, you will steward a nominated area within Regulatory Processes-such as Clinical Trial Applications, Labelling, Marketing Applications, License Maintenance, or Regulatory Information Management. You will own the end-to-end lifecycle of processes in your area: from design and development through implementation, continuous improvement, and customer support-ensuring compliance with applicable industry regulations and AstraZeneca Global and Local Policies. You will build strong relationships across Regulatory Affairs and relevant functions to execute strategy, govern current procedural documents, and deliver measurable business benefits.

What you'll do

* Own and be accountable for the long-term stewardship and successful delivery of business benefits across your nominated group of processes.
* Fulfil all responsibilities of the Business Process Owner (BPO; when tasks are delegated, retain accountability for setting and communicating strategy and timelines.
* Demonstrate and foster a culture of ownership and holistic, efficient issue management that meets business needs and ensures top-tier customer and stakeholder engagement.
* Engage and influence key internal and external stakeholders (also beyond Regulatory) to drive strategy, development, and continuous improvement of processes, technology, and services.
* Ensure customer requirements are understood, critically evaluated, prioritised, and addressed; partner with line managers and leadership to align needs and resources and provide clear rationale for non-addressed areas.
* Ensure internal processes are fit for purpose and lead improvements with relevant stakeholders.
* Partner with Systems counterparts to drive an integrated, holistic approach across processes and systems.
* Act as the primary escalation point for risks and issues within the assigned area.
* Monitor overall performance of processes and technology; track KPIs, oversee timely and quality CAPAs, and act on insights from Quality & Risk Management.
* Actively seek and promote creative, innovative ideas that drive performance and bring new solutions to customers.
* Project manage to agreed targets and provide expert operational and/or strategic regulatory or pharmacovigilance input to cross-functional teams.
* Ensure relationships and interfaces are managed effectively across internal teams and with external partners.

Essential requirements

* University degree or equivalent qualification in a relevant scientific discipline.
* Knowledge and understanding of global regulatory and pharmacovigilance requirements, balanced with industry standards to achieve business goals.
* Experience in design, development, implementation, maintenance, continuous improvement, and customer support for business processes in the area of focus.
* Experience authoring standards documents (e.g., Standard Operating Procedures).
* Experience developing and delivering training via virtual meetings and other media.
* Experience leading teams as a line manager or project lead.
* Ability to manage multiple stakeholders effectively.
* Extensive knowledge and skills in project management, specifically in leading teams.
* Demonstrated excellent written and verbal communication skills.
* Able to work with a high degree of autonomy.
* Able to represent AstraZeneca externally where required.

Desirable requirements

* PhD in a scientific discipline.
* Knowledge of new and developing regulatory and pharmacovigilance expectations.
* Experience with inspection activities.

Key capabilities

* Understanding of governance processes.
* Process improvement expertise (e.g., Lean methodology).
* Strong collaboration and coordination skills.
* Financial acumen and resource prioritisation.
* Ability to drive outcomes across matrix teams.
* Open to multiple perspectives, with a balanced, solution-focused approach.

So, what's next?
If this sounds like you, we're ready to hear your story and explore how you can help us advance regulatory excellence and deliver for patients.

We're looking forward to your application! Visa mindre

Are you an in vivo biologist who thrives at the bench and wants to turn cutting-edge genome engineering into transformative therapies for rare diseases? Do you want to collaborate across disciplines to translate innovative editing technologies into robust, decision-driving in vivo data. Join us to design, deliver, and optimize next?generation editors directly in mice to advance curative gene therapies.

We have a great opening for a Senior Scientist with demonstrated expertise in in vivo mouse studies and genome engineering. You will join the Genome Engineering In Vivo Models team, within Discovery Sciences and focuse on in vivo genome modification in mouse models. The role is located at our vibrant R&D site in Gothenburg, Sweden.

What you'll do?
This is a laboratory-based role, where you will plan and conduct end to end mouse studies, including dosing, tissue collection, necropsy, and sample processing in accordance with ethical and regulatory standards. You will also prepare and administer CRISPR/Cas9, base and prime editors, guide RNAs, and donor templates via appropriate routes (e.g., IV, IP, IT, IM) and modalities (e.g., AAV, LNP, viral and non viral systems).



Typical accountabilities will include:

*

Data generation and analysis: Quantify on target editing and functional outcomes using NGS (targeted amplicon or capture), qPCR/dPCR, and protein/biomarker assays; contribute to off target risk assessment
*

Study design and optimization: Optimize dose, route, schedule, tissue targeting, and delivery vehicle selection across relevant strains and disease models to meet program objectives
*

Documentation and reporting: Maintain accurate records, ensure data integrity and traceability, and deliver clear study reports and presentations to drive project decisions
*

Cross-functional collaboration: Partner with genome engineering, pathology, and bioinformatics teams to troubleshoot, interpret data, and advance milestones



Essential requirements for the role:

*

Ph.D. or equivalent industrial/academic experience in a relevant discipline (e.g., in vivo pharmacology, molecular biology, genetics, biomedical engineering)
*

Hands on expertise with in vivo mouse procedures
*

Practical experience with genome editing technologies; experience translating in vitro to in vivo preferred
*

Proficiency in analysis of genome editing outcomes from in vivo samples (NGS, qPCR/dPCR, protein/biomarker quantification)
*

Strong organizational, documentation, and data management skills; proficiency with electronic lab notebooks and sample tracking
*

Effective communication skills and a collaborative working style with a delivery focus
*

Compliance with institutional animal care and welfare standards is required; relevant certifications are preferred



Why AstraZeneca?
At AstraZeneca, we are united by a common purpose: to push the boundaries of science to deliver life changing medicines. You will join an inclusive, science led organization with the resources and cross functional expertise to translate innovative genome engineering into therapeutic impact.

What's next?
If this sounds like the place and job for you - welcome to apply today! We look forward to get to know you better. Send in your application no later than January 16, 2026. For more information about the position please contact hiring manager Michelle Porritt at [email protected]

Please note: Due to the holiday season, our response to your application may take longer than usual. Thank you for your patience-we will follow up when we return in January. Visa mindre

Göteborgs universitet möter samhällets utmaningar med mångsidig kunskap. 58 000 studenter och 6800 medarbetare gör universitetet till en stor och inspirerande arbetsplats. Stark forskning och attraktiva utbildningar lockar forskare och studenter från hela världen. Med ny kunskap och nya perspektiv bidrar Göteborgs universitet till en bättre framtid.Institutionen för kliniska vetenskaper är en av sex institutioner vid Sahlgrenska akademin vid Göteborgs universitet. Vid institutionen bedrivs forskning och utbildning som sätter människans hälsa och livskvalitet i fokus. Vi representerar 16 olika ämnesområden och är indelade i fyra sektioner. Genom ett berikande samarbete med sjukvården och Sahlgrenska Universitetssjukhuset har vi utvecklat samprojekt och mötesplatser som gynnar både vården och forskningen. 

På avdelningen för onkologi bedrivs forskning och undervisning om icke-kirurgiska behandlingsmetoder av tumörsjukdomar, t ex immunterapi, strålbehandling, cellgiftsbehandling och hormonbehandling.

Max Levins forskargrupp studerar kopplingen mellan biverkningar och effekt vid cancerbehandling med immunterapi (immuncheckpoint hämmare). Den utlysta anställningen syftar till att identifiera immunmekanismer bakom exceptionellt bra respons på immunterapi och innefattar analys av ett unikt kliniskt material från mer än 250 cancerpatienter som följts med regelbunden provtagning i upp till 8 års tid.



Ämne 
Onkologi

 

Ämnesbeskrivning 
Modern immunterapi med checkpoint inhibitorer har revolutionerat cancerbehandling och botar vissa patienter med tidigare obotlig cancer. Samtidigt saknar ungefär hälften av patienterna effekt av behandlingen och dör av sin sjukdom. 

Vår forskargrupp detaljstuderar immunförsvaret hos patienter som svarar extremt bra på behandling. Framförallt är vi intresserade av att förstå varför vissa specifika biverkningar är kopplade till extremt bra behandlingseffekt. Under de senaste 8 åren har vi samlat ihop en omfattande klinisk kohort av patienter med denna typ av biverkningar och följt de över tid, i vissa fall många år. Vi samarbetar med framstående immunologer lokalt på Sahlgrenska och internationellt på NIH, Dana Farber och INSERM i Marseille.

 

Arbetsuppgifter 
Det övergripande målet med projektet är att kartlägga immunmekanismer i blod och tumörer hos cancerpatienter med responskopplade biverkningar. Detta innebär omfattande analyser av ett unikt kliniskt material. De tekniker som används inkluderar cellodling av immunceller och tumörceller, flödescytometri, singel cell RNA sekvensering av immunceller från cancerpatienter, T-cellsklonalitetsanalys, CITE-sequencing, flödescytrometry, proteomik, multiplex immunfluorescens och spatial transcriptomics. Resultaten analyseras med bioinformatiska metoder.

 

Behörighet 
Behörig att anställas som postdoktor är den som har avlagt doktorsexamen eller som har en utländsk examen som bedöms motsvara doktorsexamen. Detta behörighetskrav ska vara uppfyllt senast vid tidpunkten då anställningsbeslutet fattas.

I första hand bör den komma i fråga som har avlagt examen högst tre år före ansökningstidens utgång. Även den som avlagt examen tidigare bör komma i fråga i första hand, om det finns särskilda skäl. Med särskilda skäl avses ledighet på grund av sjukdom, föräldraledighet, förtroendeuppdrag inom fackliga organisationer, tjänstgöring inom totalförsvaret, eller andra liknande omständigheter samt klinisk tjänstgöring eller för ämnesområdet relevant tjänstgöring/uppdrag. 

  

Bedömningsgrunder 
Sökanden ska ha en grundutbildning och doktorsexamen inom molekylärbiologi, biomedicin, läkare eller motsvarande. Doktorsexamen inom onkologi eller immunologi/inflammationsforskning är särskild meriterande.

Dokumenterad erfarenhet av laborativt arbete och bioinformatiska analyser är en merit.

Stor vikt läggs vid personliga egenskaper, särskilt förmågan att arbeta självständigt och att ha god organisatorisk förmåga. Kandidaten förväntas självständigt planera, utföra och analysera experiment samt aktivt bidra vetenskapligt till forskargruppen. Sökanden ska ha utmärkta generella forskningsfärdigheter, god skriftlig förmåga och kunna arbeta både självständigt och i team. Mycket god förmåga att uttrycka sig på engelska, både muntligt och skriftligt, är nödvändig.

 

Anställning 
Anställningen är en tidsbegränsad anställning på 100% i 24 månader, med placering vid Institutionen för kliniska vetenskaper, Avdelningen för onkologi. Tillträde: Enligt överenskommelse

  

Kontaktuppgifter för anställningen 
Har du frågor om anställningen är du välkommen att kontakta adjungerad professor Max Levin på telefon 0708175499 eller e-post [email protected]. 

 

Fackliga organisationer 
Fackliga företrädare vid Göteborgs universitet hittar du här:?https://www.gu.se/om-universitetet/jobba-hos-oss/hjalp-for-sokande 

 

Ansökan 
Du söker anställningen via Göteborgs universitets rekryteringsportal genom att klicka på knappen ”Ansök”. Du som sökande ansvarar för att ansökan är komplett i enlighet med annonsen och att den är universitetet tillhanda senast sista ansökningsdag.  

Till ansökan ska kopia på doktorsexamen bifogas.

 

Ansökan ska vara inkommen senast: 2026-01-08

Universitetet arbetar aktivt för en arbetsmiljö med jämställda förhållanden och sätter värde på de kvalitéer mångfald tillför verksamheten.

Universitetet tillämpar individuell lönesättning.

Enligt Riksarkivets föreskrifter är universitetet skyldigt att förvara ansökningshandlingar i två år efter tillsättningsbeslutet. Om du som sökande till en anställning särskilt begär tillbaka dina handlingar återsänds de när de två åren har förflutit, i annat fall kommer de att gallras ut.

Till bemannings- och rekryteringsföretag och till dig som är försäljare: Göteborgs universitet anlitar upphandlad annonsbyrå i samband med rekrytering av personal. Vi undanber oss vänligen men bestämt direktkontakt med bemannings- och rekryteringsföretag samt försäljare av jobbannonser. Visa mindre

Are you a strategic DMPK expert ready to lead cross-functional teams and shape project decisions? Join us in developing future treatments for Cardiovascular, Renal, and Metabolic diseases!



We are seeking a highly skilled and passionate DMPK Project Leader to join the DMPK & BBA (Drug Metabolism and Pharmacokinetics & Biomarker Bioanalysis) team within the early Cardiovascular, Renal, and Metabolism (CVRM) therapeutic area at AstraZeneca. Early CVRM is one of the three main therapeutic research areas within AstraZeneca which deliver candidate drugs into late-stage clinical development. DMPK & BBA interacts with functions like Clinical Pharmacology, Safety, Bioscience, Translational Science and Clinical Development in supporting Early CVRM projects along the value chain, from target selection all the way to market launch and life-cycle management.



This position will be based at AstraZeneca's dynamic R&D site in Gothenburg, Sweden.



Accountability

As a DMPK Project Leader, you will hold a strategic and scientific role with high visibility. You will be responsible for the overall non-clinical DMPK contribution (including pre-clinical PK, translational PK and PK/PD, biotransformation and bioanalysis) across projects from lead optimization throughout Life Cycle Management to fulfil both internal and regulatory requirements. You will work with skilled DMPK scientists and teams to manage and deliver timely high-quality input to the projects you represent. Accountabilities include:

*

Define activities to understand the DMPK properties and meet internal/regulatory requirements consistent with project milestones and timelines
*

Apply state of the art DMPK science and regulatory strategies for at least 2 different types of drug modalities (i.e. small molecules, PROTACs, peptides, biologics, oligonucleotides)
*

Evaluate, interpret and integrate DMPK data to drive project deliverables - including review and transition through internal governance bodies
*

Project manage deliverables from internal/external sources and facilitate interpretation/integration into project knowledge
*

Work collaboratively with key colleagues in the project core team as well as the DMPK design leader, Biotransformation scientists, non-clinical modelers, safety sciences and Clinical Pharmacology scientists and act as the bridge for exchanging knowledge, data and progress
*

Prepare the DMPK part of regulatory documents (e.g. IND, IMPD, IB, NDA)
*

Represent DMPK in project meetings and communications with authorities as well as in Due Diligence and in-licensing activities
*

Initiate and drive scientific strategic initiatives on internal cross Therapy Area DMPK level, or on a cross Pharma level for either MIST, ADME studies & peptides, Oligonucleotide non-clinical DMPK/BT aspects, biologics, cell therapy, PKPD modelling or discovery perspectives influencing the Development phase
*

Publish scientific papers describing the non-clinical DMPK of their projects



Essential Skills/Experience

*

PhD or equivalent in relevant field, and at least three years of experience relevant to the position
*

Broad background and comprehensive understanding of discovery and development DMPK
*

Significant experience of leading and managing projects and teams to deliver scientific and functional knowledge from lead optimization/early development to life cycle management
*

Ability to operate across operational, tactical and strategic elements of the business
*

Broad experience in pharmaceutical R&D including compiling regulatory submissions
*

Track record of delivering DMPK contribution in development settings
*

Have experience of influencing the development program from a discovery perspective
*

Good understanding of chemistry, biology, pharmacology and clinical pharmacology as well as translational medicine
*

Highly developed interpersonal, communication (written and oral), organizational and relationship building skills
*

Flexibility and ability to thrive in a rapid paced environment
*

Capable of making difficult decisions in uncertain/evolving situations
*

Proven ability to deliver high-quality solutions on time, with adequate quality and within budget in a global environment



When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.



AstraZeneca offers an environment where curiosity thrives. We are committed to making a difference by fusing data and technology with scientific innovations. Our inclusive culture encourages collaboration across academia, biotechs, and industry to create impactful solutions for complex diseases. With opportunities for lifelong learning and career development, you can explore without limits while contributing to life-changing medicines.



Ready to make an impact? Apply now to join our team at AstraZeneca!

Welcome with your application no later than December 7th, 2025. Visa mindre

At Ribocure, we are driven by science and innovation, with a mission to establish a world-leading company in RNA research and development, ultimately making a positive impact on patients worldwide. We are seeking a Trial Lead (clinical study manager) to join our growing Clinical Operations team and take a leadership role in driving the successful execution of our clinical trials.
In this role, you will lead the operational execution of one or more clinical trials across all phases of development. You will be accountable for ensuring delivery of high-quality, compliant, and cost-effective clinical trials within agreed timelines and budgets. You will manage cross-functional collaboration within the trial team, coordinate with internal stakeholders and external service providers, and oversee all aspects of clinical trial operations, from planning through reporting and close-out.
We are looking for a candidate with experience in clinical trial leadership in the pharmaceutical or biotech industry, strong organizational and communication skills, and the ability to combine sponsor oversight with hands-on execution in a dynamic, fast-paced environment.
Key responsibilities:
Lead the Clinical Trial Team to ensure efficient planning, start-up, execution, reporting, and close-out of assigned clinical trials in compliance with ICH-GCP, regulatory requirements, and company SOPs.
Act as the operational lead and primary point of contact for all trial-related activities, ensuring delivery within scope, quality, budget, and timelines.
Provide clear leadershipand direction to the cross-functional trial team (including Medical, Data Management, Biostatistics, Pharmacovigilance, Supply Chain etc) to ensure operational alignment and proactive risk management.
Develop and maintain key trial documents such as the Clinical Trial Protocol, operational plans, and study manuals; contribute to clinical sections of regulatory submissions and trial applications.
Oversee external partners, including CROs and service providers: responsible for service provider identification, contracting, budget management, day-to-day oversight, and performance tracking to ensure quality and compliance.
Establish and maintain effective relationships with investigators, clinical sites, and CROs to support optimal site engagement, recruitment performance, and issue resolution.
Ensure efficient site management, including site selection, initiation, training, monitoring performance, and supporting timely data entry, query resolution, and deliverables.
Participate in the setup and management of clinical systems (e.g., EDC, IRT, eTMF) by contributing to CRF design, user acceptance testing, and development of completion guidelines.
Monitor trial metrics and data quality to ensure timely and accurate trial information in all tracking systems and databases.
Coordinate clinical supply planning and QP release activities in collaboration with supply chain functions.
Ensure implementation of trial-level risk management activities and proactively identify, mitigate, and communicate potential issues or deviations.
Contribute to the continuous improvement of Ribocure’s Clinical Operations processes, tools, and quality systems.

Requirements:
University degree, preferably in medical or biological science or discipline associated with clinical research
At least 5 years’ experience from within the pharmaceutical industry and proven experience of clinical development / drug development process in various phases of development and therapy areas
Comprehensive knowledge of the clinical and pharmaceutical drug development process
Excellent knowledge of ICH-GCP principles
Strong organizational skills and ability to manage multiple priorities
Excellent communication and organizational skills

Desired requirements:
Experience in managing early clinical trials
Project management certification
Why Join Us?
We offer more than a job – we offer a mission. You’ll be part of a tight-knit, friendly team working on real challenges with real potential. Your ideas matter. Your work matters. And your growth matters to us.
Ready to Apply?We encourage you to submit your CV and cover letter promptly, as applications will be reviewed on an ongoing basis. Final application deadline: 14th of December.

Hiring manager: Rebeckha Magnusson, Head of Clinical Operations & QA Visa mindre

Are you motivated by using your data science skills to drive biological insights and are seeking a role where your expertise can make an extraordinary impact? This is an opportunity to join a dynamic and enthusiastic environment, whilst delivering critical support to drug discovery projects.



Join a place built on innovation and creativity. We harness digital, data science & AI to fast-forward our research. Making sure work born in a lab can make a real difference. Every day, impacting patients' lives across the world.



As a Director, Biostatistics and Informatics, you'll be part of the Data Sciences & Quantitative Biology department within Discovery Sciences - a global, diverse and delivery focused department where we collaborate to support drug projects aiming to impact patients' lives. In partnership with our experimentalist colleagues and other data scientists, we provide computational analysis and solutions to enable and enhance output from our technical platforms driving our drug discovery efforts. The role is based at our vibrant R&D site in Gothenburg, Sweden.



What you'll do

You will lead, mentor and develop the team and collaborate across functions to evolve our computational approaches and their drug discovery applications, to drive impact and deepen scientific excellence. We will rely on you to initiate and lead both internal and external collaborations and partnerships to ensure that we are at the cutting edge of technology and innovation.


We truly believe that everyone contributes with a unique set of competence. Your curiosity and passion for personal development combined with support from colleagues, mentors and leaders, will ensure you maximise your potential and contribution, building from your current skills, abilities and experience.


Essential for the role

Our team is a highly collaborative group of scientists, working in a constantly evolving technical and scientific landscape. Therefore, you'll have to be comfortable working at a fast pace, with a team-focused approach. You have excellent communication skills and a proactive and delivery-focused approach.


Regardless of your current level of leadership experience, you're passionate about supporting your staff and wider colleagues' development, as well as driving your own personal development and maximising your team's and individual contribution to drug discovery.


You also have:

*

PhD, or equivalent, in bioinformatics, mathematics, computer science, statistics, engineering or the life sciences
*

Expertise in omics, particularly NGS based technologies
*

Expertise in biostatistics including Frequentist statistics, Bayesian statistics and Design of Experiments
*

In-depth experience with drug discovery and AZ R&D disease area priorities and proven experience with impacting drug discovery projects across multiple disease areas.
*

In-depth experience with delivering statistical solutions to early drug discovery
*

In-depth experience of manipulating and analysing large high dimensionality unstructured datasets, drawing conclusions, defining recommended actions, and reporting results across stakeholders
*

Excellent written and verbal communication, business analysis, and consultancy skills
*

Experience in a complex global organization
*

A track record of people leadership



Desirable for the role

*

Comfortable working in high performance computing or cloud environment
*

Proven track record of publishing relevant results and tools in peer-reviewed journals, conferences, and other scientific proceedings.
*

Experience in novel methods development and application
*

Experience in influencing and controlling budgets



The successful candidate can operate effectively in a multi-disciplinary research environment. You enjoy teamwork, have a collaborative nature and will be an encouraging colleague to all.



Work policy
When we put people in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. This role is located in Gothenburg, Sweden and is not available for remote work or with travel support.

What's next?
If this sound like the position and place for you - apply today!
We look forward to receiving your application, but no later than November 10, 2025. The interview process will be ongoing, do not hesitate to apply early.

More information
For more information about the position please contact the hiring manager Natalie van Zuydam, [email protected]

Additional information
Our Gothenburg site: https://www.astrazeneca.com/our-science/gothenburg.html
Life in Gothenburg: https://www.movetogothenburg.com/
About AstraZeneca R&D: https://www.astrazeneca.com/r-d.html Visa mindre

The University of Gothenburg tackles society’s challenges with diverse knowledge. 56 000 students and 6 600 employees make the university a large and inspiring place to work and study. Strong research and attractive study programmes attract researchers and students from around the world. With new knowledge and new perspectives, the University contributes to a better future.The Guibentif lab is looking to recruit a researcher. We are affiliated to the University of Gothenburg (GU), one of the largest universities in Northern Europe. Given our affiliation to the Institute of Biomedicine and to the Sahlgrenska Center for Cancer Research, we are part of a supportive interdisciplinary environment, comprising basic developmental biologists as well as clinical scientists.

The Institute of Biomedicine is involved in both research and education. In both of these areas, we focus on fundamental knowledge of the living cell – what it consists of, how it works, how its function is directed by the genetic material, and how it interacts with various kinds of micro-organisms. Using this knowledge, we try to elucidate the causes of diseases, and find new ways to diagnose and treat them.

Duties 
The selected candidate will be expected to work in a cross-disciplinary team, and to establish single-cell profiling analysis workflows to dissect developmental processes modelled in stem cell differentiation cultures. The selected candidate will carry out aseptic cell culture and molecular biology experiments, will be involved in mentoring students in the lab, and will be expected to take part in manuscript writing and to regularly present his/her own work in group and departmental meeting.

Qualifications 
PhD in the field of stem cell biology and development. In addition, demonstrated skills in single-cell profiling techniques, human pluripotent stem cell culture and differentiation, flow cytometry and confocal imaging will be highly valued.

Employment 
The employment is limited (temporary) for 11 months and full-time with placement at the Institute of Biomedicine. First day of employment as agreed.

Contact information for the post 
If you have any questions about the position, please contact researcher Carolina Guibentif, phone: +46702253076, email: [email protected]

Unions 
Union representatives at the University of Gothenburg can be found here:?https://www.gu.se/om-universitetet/jobba-hos-oss/hjalp-for-sokande 

Application 
To apply for a position at the University of Gothenburg, you have to create an account in our recruitment system. Submit your application via the University of Gothenburg’s recruitment portal by clicking the “Apply” button. It is your responsibility to ensure that the application is complete as per the vacancy notice, and that the University receives it by the final application deadline. 

The application should contain:

- A cover letter giving a brief description of previous research experience, and a motivation to why you are applying

- A CV including a list of publications

- Proof of completed PhD

- Contact details of two references

Applications must be received by: 2025-11-11

The application should contain proof of completed PhD.

The University works actively to achieve a working environment with equal conditions, and values the qualities that diversity brings to its operations.

Salaries are set individually at the University.

In accordance with the National Archives of Sweden’s regulations, the University must archive application documents for two years after the appointment is filled. If you request that your documents are returned, they will be returned to you once the two years have passed. Otherwise, they will be destroyed.

In connection to this recruitment, we have already decided which recruitment channels we should use. We therefore decline further contact with vendors, recruitment and staffing companies. Visa mindre

Are you an enthusiastic scientist with skills in the field of membrane protein biology and have a passion to use your skills to contribute to the development of medicine to patients? Do you also want to join a place where our team work and collaborative atmosphere drives us forward? If yes, this might be the position for you!

Right now, we have an opportunity for a motivated Research Scientist to join the Membrane Protein Science Team at our vibrant AstraZeneca R&D site in Gothenburg, Sweden, for a one year temporary position. In this role you’ll play an important part in the Discovery Biology department within the Discovery Sciences organisation.

About the position
This is a laboratory-based research position where you will apply your skills and knowledge in protein purification and recombinant protein expression, your curiosity, combined with strong team working ethics to support our early drug discovery projects. You will join our team whose remit is to deliver impactful recombinant membrane protein reagents used to power hit-finding, lead-generation, all the way to clinical candidate validation.

Responsibilities
As a Research Scientist in the Membrane Protein Science Team you will be generating tailored membrane protein reagents to support projects in all phases of the discovery process. The role involves expression screening of constructs in eukaryotic hosts, large scale expression, and purification of recombinant membrane proteins to supply bioreagents to assay development, affinity screening and structure-based drug discovery.

You will plan and conduct experimental strategies and generate, interpret and report scientific data autonomously or in collaboration with colleagues. In addition, you will contribute to advance our capabilities in the production of recombinant membrane proteins used in early drug discovery.

About the organisation
This is a consultant assignment for 1 year at AstraZeneca in Göteborg.
During this time you will be hired by QRIOS.
QRIOS Life Science can offer several opportunities for skilled people with a background in biochemistry, chemical engineering or science. We work with Sweden’s leading pharmaceutical and life science companies. So whether you’re interested in research, regulatory affairs, quality assurance, environmental and quality control, sales and marketing, or just want a career change, we have the job for you.

About Astra Zeneca:
AstraZeneca is a major international healthcare company engaged in the research, development, manufacture and marketing of prescription pharmaceuticals and the supply of healthcare services. But we are more than one of the world’s leading pharmaceutical companies - at AstraZeneca, we are proud to have a unique culture that inspires innovation and collaboration. Here, employees are empowered to express diverse perspectives - and are made to feel valued, energized and rewarded for their ideas and creativity. Visa mindre

Are you an experienced scientist with great expertise in Next Generation Sequencing and Molecular Biology? Do you want to use this expertise to contribute to the discovery of novel oligonucleotide therapies? We have an opening suitable for you!

Right now, we are looking for a passionate and hard-working Molecular Biologist with NGS skills to join our NGS & Transcriptomics function within the Centre of Genomic Research Department at AstraZeneca in Gothenburg, as one of our group members is going on parental leave. You will contribute with your expertise in applying molecular biology and NGS to the discovery of novel oligonucleotide therapies.

AstraZeneca’s ambition is to become world-leading in in the field of oligonucleotide therapies. We are achieving this through advances in oligonucleotide science and innovation internally and through the establishment of key collaborations outside AstraZeneca. To this end, we currently have a portfolio of very high-profile projects at different phases of drug discovery within AstraZeneca, and you will directly contribute to their successful progression to oligonucleotide therapies.

Responsibilities
This lab-based role is for a Molecular Biologist with significant NGS expertise, which you will apply to the characterization and profiling of the effects of oligonucleotide treatments in in vitro and in vivo cellular assays and models in support of novel drug discovery projects.
Our team is a collaborative group, and you will engage in the supervision and mentorship of other scientists, ensuring that methods run expertly and accurately, developing and guiding the setup of new techniques. Included in the role is also to nurture strong collaborative relationships with the project investigators, key partners, and data scientists to ensure the smooth running of projects.

About the organisation
This is a consultant assignment for 1 year at AstraZeneca in Göteborg.
During this time you will be hired by QRIOS.
QRIOS Life Science can offer several opportunities for skilled people with a background in biochemistry, chemical engineering or science. We work with Sweden’s leading pharmaceutical and life science companies. So whether you’re interested in research, regulatory affairs, quality assurance, environmental and quality control, sales and marketing, or just want a career change, we have the job for you.

About Astra Zeneca:
AstraZeneca is a major international healthcare company engaged in the research, development, manufacture and marketing of prescription pharmaceuticals and the supply of healthcare services. But we are more than one of the world’s leading pharmaceutical companies - at AstraZeneca, we are proud to have a unique culture that inspires innovation and collaboration. Here, employees are empowered to express diverse perspectives - and are made to feel valued, energized and rewarded for their ideas and creativity. Visa mindre

Are you passionate about transforming science into clear and compelling regulatory documents that drive successful drug development? We are seeking a talented and experienced Associate Director, Clinical Regulatory Writing to join our CVRM (Cardiovascular, Renal, Metabolic) Clinical Regulatory Writing team in Gothenburg, Sweden. With more than 2,400 employees from over than 50 countries, our vibrant Gothenburg site is a truly inspiring place to work- where the history and future of scientific breakthroughs come together. We believe that the diversity of our people is crucial to bringing new discoveries to life.

About AstraZeneca

AstraZeneca is a global, science-led biopharmaceutical company dedicated to discovering, developing, and delivering innovative medicines that transform lives. Operating in over 100 countries and supported by a robust pipeline, our work addresses some of the world's most serious illnesses across oncology, cardiovascular, renal, metabolism, respiratory, and immunology. Driven by our values and innovation-led culture, we are focused on making a meaningful difference to patients, healthcare systems, and society as a whole.



About the Role

The CVRM Clinical Regulatory Writing group provides expert strategic leadership and communications expertise to clinical drug programs, ensuring delivery of high-quality, label-focused documents aligned with project strategy, regulatory requirements, and communications best practices. Role holders not only author critical clinical-regulatory documents but also act as critical reviewers to achieve the highest quality standards. Team members also represent the Clinical Regulatory Writing skill set on both drug and non-drug projects, advocating for best practices and continuous improvement.



Key Responsibilities

As an Associate Director, Clinical Regulatory Writing, you will:

* Provide strategic leadership and communication expertise to clinical drug programs across the CVRM portfolio.
* Author and critically review clinical-regulatory documents, ensuring the highest regulatory, technical, and quality standards.
* Represent Clinical Regulatory Writing on project teams, advocating for communication best practices.
* Provide strategic communications leadership within clinical delivery or submission teams, establishing standards and promoting quality and efficiency.
* Act as submission lead, driving development of the clinical Submission Communication Strategy (cSCS).
* Lead both internal and external authoring teams and cultivate strong partnerships with vendor medical writers to ensure timely, high-quality document delivery.
* Translate complex clinical data into clear, concise, and accurate messages tailored to specific audiences.
* Serve as a strategic thinker who can conduct high-level document reviews.
* Collaborate proactively with other functions at the program level.
* Support the development and upskilling of colleagues within the Clinical Regulatory Writing function.
* Champion continuous improvement and operational excellence in communications.



Essential Requirements

* Bachelor's degree in Life Sciences or a related discipline.
* Significant medical writing experience within the pharmaceutical industry or a Contract Research Organization (CRO).
* Proven ability to advise and lead communications projects and teams.
* Strong understanding of drug development and the communications process from early development through to launch and lifecycle management.
* In-depth knowledge of technical and regulatory requirements relevant to clinical regulatory writing.



Desirable Qualifications

* Advanced degree in a scientific discipline (e.g., Ph.D.).



If you are driven to deliver impactful regulatory communications, excel in multidisciplinary teams, and want to shape the future of clinical development, we encourage you to apply.



Apply with your cover letter and CV by 24 August!



Explore more about:

Gothenburg site: https://www.astrazeneca.com/our-science/gothenburg.html
Inclusion & Diversity at AstraZeneca: https://careers.astrazeneca.com/inclusion-diversity

Sustainability at AstraZeneca: https://www.astrazeneca.com/sustainability/resources.html Visa mindre

Göteborgs universitet möter samhällets utmaningar med mångsidig kunskap. 56 000 studenter och 6 600 medarbetare gör universitetet till en stor och inspirerande arbetsplats. Stark forskning och attraktiva utbildningar lockar forskare och studenter från hela världen. Med ny kunskap och nya perspektiv bidrar Göteborgs universitet till en bättre framtid. 

Vid Institutionen för medicin, Avdelningen för reumatologi och inflammationsforskning, är huvudtema för den forskning som bedrivs inflammation och inflammatoriska sjukdomar, oavsett om den orsakats av allergi, infektion eller är en autoimmun sjukdom. Målet är att utreda de mekanismer som ligger bakom inflammationen. Flera av våra forskare arbetar även som specialistläkare vid klinikerna inom Sahlgrenska universitetssjukhuset, vilket är en stor tillgång allra helst för translationell forskning.



ARBETSUPPGIFTER
Projektet är en del av ett större tvärvetenskapligt forskningsuppdrag med målet att översätta den grundläggande biologin bakom A-till-I RNA-redigering till terapeutiska tillämpningar vid kroniska sjukdomar. Den person som anställs kommer att ha ett självständigt ansvar för att utforma, planera och leda det definierade forskningsprojektet.

Arbetsuppgifterna innefattar att genomföra in vitro-analyser av cellulärt upptag samt att studera biodistributionen av siRNA och antisensoligonukleotider (ASO) i djurmodeller. Arbetet omfattar även dokumentation och tolkning av fysiologiska och patologiska utfall.

Du förväntas arbeta med avancerade cellbiologiska tekniker och histologiska metoder, inklusive immunofluorescens och bildanalys. Forskaren kommer även att använda biokemiska metoder samt kromatografiska och immunaffinitetsbaserade tekniker för att rena och karakterisera extracellulära vesiklar.

Tjänsten kräver noggrann dokumentation av experimentella metoder och säker lagring av forskningsdata. Du kommer att analysera data med hög grad av självständighet, bidra till vetenskapliga publikationer och forskningsansökningar samt aktivt handleda studenter i forskargruppen.
 

KVALIFIKATIONER 
Sökande ska ha en doktorsexamen inom ett område som motsvarar eller är relaterat till medicin, experimentell patologi eller biomedicin. Gedigen kunskap inom biokemi och molekylärbiologi är ett krav. Den sökande ska ha dokumenterad vetenskaplig produktivitet, vilket ska styrkas genom publikationer i referentgranskade tidskrifter, särskilt inom områden relevanta för tjänsten.

Meriterande är erfarenhet av: isolering av primära celler från däggdjur med hjälp av murina modeller, odling av humana och murina cellinjer samt transfektioner med plasmider eller icke-virala leveranssystem, cellulära upptagsanalyser av siRNA, antisensoligonukleotider (ASO) och mRNA. Det är även meriterande med erfarenhet av kvantitativ analys med qPCR och nukleinsyrabaserad hybridiserings-ELISA samt tidigare erfarenhet av RNA-redigering.

Praktisk erfarenhet av avancerad fluorescensmikroskopi, live-cell imaging och immunocytokemi är ett krav. God kännedom om biodistributionsstudier, inklusive immunhistokemi på vävnadssnitt, är också nödvändig. Kunskap om isolering och rening av extracellulära vesiklar, främst med kromatografibaserade metoder, samt karakterisering enligt MISEV2023-riktlinjer betraktas som meriterande.

Vi förväntar oss att sökande har god samarbetsförmåga, kommunikativ kompetens och trivs med att arbeta i en teamorienterad miljö. Den ideala kandidaten är en lagspelare med ett målinriktat, analytiskt och problemlösande arbetssätt. Mycket goda kunskaper i engelska, både i tal och skrift, är ett krav. Förmågan att arbeta strukturerat och dokumentera sitt arbete noggrant ska tydligt framgå. Vi lägger stor vikt vid personlig lämplighet.



ANSTÄLLING 
Anställningen är ?tillsvidare, deltid på en omfattning av 50%, med placering tills vidare vid Institutionen för medicin. Tillträde enligt överenskommelse. Provanställning på sex månader kan komma att tillämpas.



KONTAKTUPPGIFTER FÖR ANSTÄLLNINGEN
För frågor om projektet, ämnet, arbetsinnehåll eller arbetsplatsen är du välkommen att kontakta: Avdelningschef och forskare Mattias Svensson, +46 (0)31-786 67 06, [email protected] 

Har du frågor om ansökan, rekryteringsprocessen och anställningsvillkor är du välkommen att kontakta personalhandläggare Cecilia Groglopo, +46 (0)31 786 6261, [email protected]
 

FACKLIGA ORGANISATIONER 
Fackliga företrädare vid Göteborgs universitet hittar du här:?https://www.gu.se/om-universitetet/jobba-hos-oss/hjalp-for-sokande 



ANSÖKAN 
Du söker anställningen via Göteborgs universitets rekryteringsportal genom att klicka på knappen "Ansök" längst ned i annonsen. Du som sökande ansvarar för att ansökan är komplett i enlighet med annonsen och att den är universitetet tillhanda senast sista ansökningsdag. 

Vänligen lämna in följande dokument som en del av din ansökan:
- Personligt brev: En kort beskrivning av din tidigare forsknings erfarenhet, din motivation för att söka denna tjänst och annonsens referensnummer.
- Curriculum Vitae (CV): Inkluderande en komplett lista över publikationer.
- Examensbevis: Kopior av relevanta akademiska examensbevis.
- Referenser: Namn, tillhörighet och kontaktinformation till minst två referenser som kan tala om dina kvalifikationer och erfarenheter.



Ansökan ska vara inkommen senast: 2025-09-02

 

Universitetet arbetar aktivt för en arbetsmiljö med jämställda förhållanden och sätter värde på de kvalitéer mångfald tillför verksamheten.

Universitetet tillämpar individuell lönesättning.

Enligt Riksarkivets föreskrifter är universitetet skyldigt att förvara ansökningshandlingar i två år efter tillsättningsbeslutet. Om du som sökande till en anställning särskilt begär tillbaka dina handlingar återsänds de när de två åren har förflutit, i annat fall kommer de att gallras ut.

Till bemannings- och rekryteringsföretag och till dig som är försäljare: Göteborgs universitet anlitar upphandlad annonsbyrå i samband med rekrytering av personal. Vi undanber oss vänligen men bestämt direktkontakt med bemannings- och rekryteringsföretag samt försäljare av jobbannonser. Visa mindre

Location: Gothenburg, Sweden
Start Date: September 2025
Contract Type: Consultant assignment via Poolia


Are you passionate about analytical chemistry and eager to apply your skills in a modern research environment? Do you thrive in a hands-on, collaborative setting? This is your opportunity to join an advanced R&D laboratory as a consultant through Poolia, starting in September 2025.

We are currently seeking an Analytical Chemist / Scientist to support a leading pharmaceutical research team specializing in separation science. In this lab-based role, you will use cutting-edge chromatographic technologies to purify and characterize compounds that contribute directly to drug discovery and development


About the position
You will work as part of a cross-functional team contributing to early pharmaceutical development by:
• Performing laboratory-based work with modern chromatography systems
• Operating and maintaining a variety of chromatographic equipment
• Collaborating with scientists from other disciplines in a highly integrated environment
• Delivering high-quality analytical results to support ongoing R&D projects


Your profile

• Solid scientific knowledge in analytical chemistry
• Hands-on experience with chromatographic methods and equipment
• Strong problem-solving skills and technical curiosity
• Excellent communication skills in English (both spoken and written)
• A collaborative mindset and the ability to prioritize and take initiative
Preferred Qualifications

• Experience with preparative chromatography
• Familiarity with detection techniques such as UV, MS, or ELSD

________________________________________


About the organisation
This consultant role is ideal for those who want to gain broad experience in a short amount of time. We offer you the chance to work at popular workplaces with well-known brands, where you can develop your skills and strengthen your CV.

You’ll thrive as a consultant if you’re looking for a world of exciting assignments and opportunities to expand your professional network. Throughout your assignment, your dedicated consultant manager will be by your side to support you and act as a sounding board to help you succeed in your role.

At Poolia, your well-being and job satisfaction are important to us. That’s why we offer wellness benefits, discounts at various gyms and fitness centers, and regularly organize social activities.

Naturally, your employment with Poolia includes collective agreements, insurance, occupational pension, and access to occupational health services. Visa mindre

In Pharmaceutical Technology and Development (PT&D) we are the bridge which turns forward-thinking science into actual medicines that help millions of people around the world. We work across the entire value chain, crafting and delivering active ingredients, formulations and devices required to support new medicines – from supplies for use in early toxicology studies and clinical trials to developing the technology to ensure drugs can be scaled up for commercial manufacture.
The Clinical Supply Associate (CSA) supports the clinical supply management team with task-based activities to ensure high-quality and timely delivery of materials to clinical trial patients. This role is a great opportunity for someone who thrives working in an agile, vibrant and global environment.

About the position
The CSA supports teams with task-based activities that include:

• Management of temperature excursion assessments affecting clinical trial material.
• Electronic document archiving and quality control.
• User Acceptance Testing of digital systems.
• Support the coordination of the purchase and delivery of External Commercial Products.
• Facilitation of documentation activities ensuring inspection readiness to meet international GMP standards.
• Coordination of ID testing requests of clinical trial material.
• Documentation and coordination of product quality complaints and GXP deviations.
• Utilising Supply Chain Management systems to support agile ways of working.
• Continually improving the Clinical Supply Chain processes through visual management, problem solving, global standardisation and process confirmation.

Responsibilities
In this role you will have the opportunity to develop leadership skills and enterprise acumen, quickly becoming a super-user within a core role and/or leading improvement initiatives. You will work with multiple colleagues, customers and partners internally and externally across all phases of the drug development lifecycle, covering small and large molecule drug products. You will follow SHE and GXP standards and will be personally accountable for these areas within your own work plans.

Your profile
Essential for the role:
• Degree and/or Masters in a scientific discipline or supply chain management
• Proven track record of critical thinking under pressure.
• A supply chain management ambition.
• Excellent aptitude for digital systems and an active interest in GenAI.
• Thrives in a process orientated workplace, on task-based activities and with a focus on the customer/patient.
• Team player with a structured problem-solving mindset and a focus on quality.
• Comfortable in a high paced and agile environment.
• Excellent communication and numeracy skills.

About the organisation
This position is a consultant assignment at AstraZeneca for 12 months.
During this time you will be employed by QRIOS Life Science & Engineering.
QRIOS employs curious experts in IT, Life Science and Engineering. We want to continue to attract the best employees, to continue to support our partners with the important competences you require. We are a recruitment and consulting company that is strongly inspired by those who never stop looking for new solutions. As we say, QRIOS MINDS GO FURTHER Visa mindre

Are you an experienced Discovery Safety Specialist/Toxicologist? Would you like to bring your scientific excellence to BioPharma Safety and become a key player in the discovery of safe innovative medicines? If yes, this might be your next career step!

We are looking for a motivated individual to join us as an Associate Director, Discovery Safety Specialist/Toxicologist to strengthen the BioPharma Discovery Safety team with a focus on cardiovascular, renal, metabolism and respiratory drug projects. You will bring critical safety-expertise to BioPharma Safety within the larger function of Clinical Pharmacology and Safety Sciences (CPSS). The position will be placed either at our vibrant R&D site in Gothenburg, Sweden or in Cambridge Biomedical Campus, UK.

The BioPharma Discovery Safety team develop and apply innovative scientific strategies to drive the design and selection of safe medicines for patients suffering from Cardiovascular, Renal and Metabolic (CVRM) diseases as well as respiratory diseases.

Within Clinical Pharmacology and Safety Sciences, we put a strong emphasis on talent development. You will be able to develop your scientific leadership by working together with leaders in investigative toxicology, drug discovery, cell biology, and predictive safety science.



Accountabilities:
As true Drug Hunting partners to BioPharma R&D, we contribute to the selection of novel drug targets, design of therapeutic concepts, identification and optimization of different modalities, and the selection of novel candidate drugs. We develop and apply cutting edge molecular, cellular and in vivo technologies to push the boundaries of predictive safety science and investigative toxicology.

You will also be responsible for the safety strategy in multi-disciplinary drug discovery project teams and provide scientific leadership to influence project decision making with the aim to deliver molecules with the Right Safety profile. As well as:

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Design and build in vitro and in vivo strategies to predict, assess, and mitigate on-target, off-target and drug-related safety risks and execute through internal and external experimental capabilities.
*

Develop innovative solutions and research proposals based on strategic needs of the discovery project portfolio, and to pursue cutting edge science and technologies in order to optimize and influence safety assessment of novel drugs.
*

Engage with world-class experts across our organization to develop, refine and implement innovative experimental strategies and use the data to assess and/or provide mechanistic understanding of safety issues.



Essential Skills/Experience:

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PhD (or equivalent) in toxicology, cell biology, pharmacology, systems biology or related field, and a strong scientific track record. Relevance on the job experience will also be considered.
*

Experience working with design of strategies and execution of in vitro and in vivo experiments to determine the safety of therapeutics (experience from different modalities e.g. small molecules, oligonucleotides, peptides and biologics).
*

Knowledge of advanced drug delivery and tissue targeting approaches across modalities. Understanding the safety aspects of targeted delivery.
*

Experience from doing Target Safety Assessments to identify on-target risks and setting up mitigation strategies.
*

Preferably >3 years' experience as Toxicologist in the drug discovery phase handling multiple drug projects in parallel.
*

Experience from external scientific collaborations. Experience of scientific mentorship e.g. leading work for a PhD student.



The successful candidate is a highly motivated, creative and innovative scientist with a flexible, collaborative and team-oriented mindset. You like to solve problems in a goal-focused fashion and you have strong communication and presentation skills. Along with this, you have a social personality and will enjoy contributing to our open, positive, collaborative working climate.



So, what's next?

Are you ready to make a meaningful and lasting difference? Apply today and join us in our mission to push the boundaries of science and transform medicine! We look forward to your application, please submit both a resume and a personal letter. Please submit your application no later than August 10, 2025. Visa mindre

We are now recruiting a Scientist to join the Automation & Assays team in Bioscience technology within Early Cardiovascular, Renal and Metabolism (Early CVRM) in our dynamic R&D site in Gothenburg, Sweden

The Automation & Assay team using advance automation platforms for molecular biology assays to enable delivery of high-quality data to build a detailed understanding of pharmacological response and mode of action for e.g. small molecules, oligos, antibodies as therapeutic drugs in our pipeline projects across the Cardiovascular, Renal and Metabolism disease areas.

About the position
As a Scientist you will primarily process tissue samples using cell surface protein enrichment techniques for proteomics to provide experimental support to our drug discovery programs, development and characterisation, and optimisation of new models. There will be possibility to be part of building automated methods for sample preparation for proteomics analysis.

Responsibilities
Responsibility includes:
• Tissue samples using cell surface protein enrichment techniques for proteomics
• Potentially take part in the assay and method development using advanced automated platforms
• Planning and execution of experiments, troubleshooting and timely reporting/presentation of data according to agreed timelines.
• Join further model development activities to support drug projects with biomarker and molecular assays for resolving mechanisms of action, target identification, and candidate drug evaluation.

Your profile
Essential Requirements:
• For the Scientist role: Master’s degree + 2 years of relevant experience.
• Background in Molecular Biology, Biomedical, Pharmacology, Biochemistry or a related discipline with significant practical experience.
• Extensive experience in molecular and cellular biology techniques and in particular protein assays and sample preparation
• Independent study design, laboratory work, and data analysis
• Excellent communication skills in English, both verbal and in writing

Desirable Experiences and abilities:
• Processing of biological samples for proteomic analysis
• Potential knowledge in Proteomics
• Independent technical capability with assay development
• Experience in automation technology such as robotic liquid handler
• Proven ability in providing technical leadership and guidance to others.
• Experience from pharmaceutical industry

Soft skills:
• Effectively communicate and collaborate in a matrix team setting to implement technical solutions
• Excellent interpersonal skills and excellent communication skills in English, both verbal and in writing
• Strong ability to engage and collaborate across boundaries with a problem-solving attitude and focus on delivery

About the organisation
This position is a consultant assignment at AstraZeneca for 12 months.
During this time you will be employed by QRIOS Life Science & Engineering.
QRIOS employs curious experts in IT, Life Science and Engineering. We want to continue to attract the best employees, to continue to support our partners with the important competences you require. We are a recruitment and consulting company that is strongly inspired by those who never stop looking for new solutions. As we say, QRIOS MINDS GO FURTHER Visa mindre

Are you ready to make a significant impact on the development of new medicines? Join us at AstraZeneca's Early Product Development and Manufacture (EPDM) unit in Gothenburg, Sweden. We are accountable for delivering a vast portfolio of early investigational medicinal products, supplying different types of clinical trial material to studies across the globe. This is your chance to explore and innovate in our dynamic environment!
This is an exciting opportunity to join our Pharmaceutical Sciences department which is accountable for the design and development of synthetic routes, preclinical and phase I/II formulations, encompassing both small molecules and new modalities such as mRNA and oligonucleotides, across the whole range of AstraZeneca’s therapeutic areas. The role will be offered at Scientist level.

About the position
As part of the EPDM manufacturing unit, you will work in a GMP (Good Manufacturing Practice) environment, contributing to the delivery of clinical results. Your role will focus on the manufacturing of drug product, with responsibilities including timely manufacture of various drug products, working with practical hands-on processes in our GMP facilities, monitoring regulatory requirements, supporting documentation activities, and driving initiatives to improve flexibility and productivity. As we are investing in innovative technology, among others within Continuous manufacture, we need to expand knowledge and competence in this area. Depending on prior experience and interest this role could be more adapted to this area.

Responsibilities
• Work with practical hands-on processes in our GMP facilities following manufacturing batch records and perform transactions in material management systems.
• Assume responsibilities toward timely manufacture of various drug products in line with the plans agreed within EPDM and surrounding stakeholders.
• Monitor, secure and follow up on other regulatory requirements according to GMP through associated IT-systems.
• Rapidly develop strong competence within relevant process technologies and build credibility and ability to drive and secure product establishment, scale-up and clinical manufactures.
• Support documentation activities, e.g. by authoring manufacturing batch records, taking part in deviation investigations, authoring SOPs, and other guidance documents, change control processes etc.
• Assess records and report manufacturing and validation data accurately according to GMP.
• Ensure that SHE (Safety Health and Environment) and GMP standards are upheld and ensure AZ Policies and Standards are understood and followed.
• Be entrepreneurial and drive initiatives to further improve flexibility and productivity, resulting in shorter lead times or increased value for our customers and patients.

Your profile
Essential for the role:
- MSc or BSc in pharmacy/engineering or extensive GMP-manufacturing experience from the pharmaceutical industry
- Excellent collaboration, communication, and planning skills
- Strong sense of responsibility, teamwork and delivery focus
- Strong verbal and documentation skills in English
- Experience from pharmaceutical development or working in a manufacturing or supply chain organisation and knowledge of GMP is a merit for this role.
- Keen interest to learn and operate complex manufacturing equipment

About the organisation
This position is a consultant assignment at AstraZeneca for 12 months.
During this time you will be employed by QRIOS Life Science & Engineering.
QRIOS employs curious experts in IT, Life Science and Engineering. We want to continue to attract the best employees, to continue to support our partners with the important competences you require. We are a recruitment and consulting company that is strongly inspired by those who never stop looking for new solutions. As we say, QRIOS MINDS GO FURTHER Visa mindre

Scientist – Early Product Development and Manufacturing at AstraZeneca in Gothenburg

We are looking for a Scientist to join the EPDM unit at AstraZeneca in Gothenburg. In this GMP-based role, you will focus on hands-on manufacturing of clinical drug products, support documentation, ensure compliance, and contribute to process improvements.

Purpose, Offer and Benefits

This is a consultant assignment starting in August and expected to last for 1 year.

This is an exciting opportunity for you to join AstraZeneca’s Pharmaceutical Sciences department which is accountable for the design and development of synthetic routes, preclinical and phase I/II formulations, encompassing both small molecules and new modalities such as mRNA and oligonucleotides, across the whole range of AstraZeneca’s therapeutic areas. The role will be offered at Scientist level.

Your Responsibilities

• Work with practical hands-on processes in our GMP facilities following manufacturing batch records and perform transactions in material management systems.
• Assume responsibilities toward timely manufacture of various drug products in line with the plans agreed within EPDM and surrounding stakeholders.
• Monitor, secure and follow up on other regulatory requirements according to GMP through associated IT-systems.
• Rapidly develop strong competence within relevant process technologies and build credibility and ability to drive and secure product establishment, scale-up and clinical manufactures.
• Support documentation activities, e.g. by authoring manufacturing batch records, taking part in deviation investigations, authoring SOPs, and other guidance documents, change control processes etc.
• Assess records and report manufacturing and validation data accurately according to GMP.
• Ensure that SHE (Safety Health and Environment) and GMP standards are upheld and ensure AZ Policies and Standards are understood and followed.
• Be entrepreneurial and drive initiatives to further improve flexibility and productivity, resulting in shorter lead times or increased value for our customers and patients.

The Bigger Picture

As part of the EPDM manufacturing unit, you will work in a GMP (Good Manufacturing Practice) environment, contributing to the delivery of clinical results. Your role will focus on the manufacturing of drug product, with responsibilities including timely manufacture of various drug products, working with practical hands-on processes in our GMP facilities, monitoring regulatory requirements, supporting documentation activities, and driving initiatives to improve flexibility and productivity. As we are investing in innovative technology, among others within Continuous manufacture, we need to expand knowledge and competence in this area. Depending on prior experience and interest this role could be more adapted to this area.

Our Expectations

• MSc or BSc in pharmacy/engineering or extensive GMP-manufacturing experience from the pharmaceutical industry
• Excellent collaboration, communication, and planning skills
• Strong sense of responsibility, teamwork and delivery focus
• Strong verbal and documentation skills in English
• Experience from pharmaceutical development or working in a manufacturing or supply chain organisation and knowledge of GMP
• Keen interest to learn and operate complex manufacturing equipment

Interested?
This is a staffing assignment which means that you are employed by TNG, but work for one of our customers. If you are interested in this position, apply right now! The selection process is ongoing and the position can be filled before the last apply-date. If you have any questions, please contact the recruiter. Visa mindre

AstraZeneca is a major international healthcare business engaged in the research, development, manufacture and marketing of prescription pharmaceuticals and the supply of healthcare services. AstraZeneca is proud to offer a unique workplace culture that inspires innovation and collaboration. Co-workers are empowered to express diverse perspectives - and are made to feel valued, energized and rewarded for their ideas and creativity.
AstraZeneca is also a leading pharmaceutical company focused on developing Active Pharmaceutical Ingredients (API) with advanced technologies. The Gothenburg facility employs digital solutions and automation to enhance production effic

About the position
The IT/OT Engineer will bridge the gap between IT and Operational Technology(equipment) in the manufacturing facility. Key responsibilities include maintaining IT systems that support business operations and manufacturing, ensuring system integrity and security, troubleshooting IT-related issues, and collaborating with various stakeholders to ensure compliance with industry standards.

Responsibilities
Tasks and responsibilities/The role:
1. IT Infrastructure Management:
Ensure the performance and availability of IT systems.
2. OT System Support:
Align IT support with production needs.
Proactively address IT-related issues affecting manufacturing.
3. Cybersecurity Management:
Implement cybersecurity measures for IT and OT systems.
Staff training on security.
4. Data Integration & Management:
Ensure smooth data flow between IT and OT systems.
Develop interfaces for real-time data exchange.
5. System Administration & Troubleshooting:
Resolve IT incidents impacting operational efficiency.
Collaborate with vendors for advanced issues.
6. Vendor and Stakeholder Management:
Manage vendor relationships and service compliance.
Coordinate IT/OT project goals with internal teams.
7. Compliance and Best Practices:
Maintain GxP compliance and thorough documentation.
Lead system audits and validations.
8. Continuous Improvement & Innovation:
Evaluate and implement new IT/OT technologies.
Mentor junior staff and lead innovation projects.

Your profile
Essential requirements:
• Education: Bachelor’s in Computer Science or related field; OT/Cybersecurity certifications preferred.
• Experience: 5+ years in IT with 2+ years in OT, especially in pharmaceutical manufacturing; experience with systems like SAP S4/HANA, Experienced in Power BI, Power Automate, MS Lists.
• Skills: Strong knowledge of IT/OT convergence, excellent problem-solving abilities, and understanding of cybersecurity best practices. GMP knowledge.

Soft skills/Personal Attributes:
Effective communication, multitasking, attention to detail, and commitment to excellence.

About the organisation
This is a consultant assignement at AstraZeneca Göteborg for 6 months starting end of May 2025. During this time you will be hired by QRIOS.

About Astra Zeneca:
AstraZeneca is a major international healthcare company engaged in the research, development, manufacture and marketing of prescription pharmaceuticals and the supply of healthcare services. But we are more than one of the world’s leading pharmaceutical companies - at AstraZeneca, we are proud to have a unique culture that inspires innovation and collaboration. Here, employees are empowered to express diverse perspectives - and are made to feel valued, energized and rewarded for their ideas and creativity. Visa mindre

Are you motivated by using your data science skills to drive biological insights and are seeking a role where your expertise can make an extraordinary impact? This is an opportunity to join a dynamic and enthusiastic environment, whilst delivering critical support to drug discovery projects.



Join a place built on innovation and creativity. We harness digital, data science & AI to fast-forward our research. Making sure work born in a lab can make a real difference. Every day, impacting patients' lives across the world.



As a Director, Biostatistics and Informatics, you'll be part of the Data Sciences & Quantitative Biology department within Discovery Sciences - a global, diverse and delivery focused department where we collaborate to support drug projects aiming to impact patients' lives. In partnership with our experimentalist colleagues and other data scientists, we provide computational analysis and solutions to enable and enhance output from our technical platforms driving our drug discovery efforts. The role is based at our site in Gothenburg, Sweden.



What you'll do

You will lead, mentor and develop the team and collaborate across functions to evolve our computational approaches and their drug discovery applications, to drive impact and deepen scientific excellence. We will rely on you to initiate and lead both internal and external collaborations and partnerships to ensure that we are at the cutting edge of technology and innovation.


We truly believe that everyone contributes with a unique set of competence. Your curiosity and passion for personal development combined with support from colleagues, mentors and leaders, will ensure you maximise your potential and contribution, building from your current skills, abilities and experience.


Essential for the role

Our team is a highly collaborative group of scientists, working in a constantly evolving technical and scientific landscape. Therefore, you'll have to be comfortable working at a fast pace, with a team-focused approach. You have excellent communication skills and a proactive and delivery-focused approach.


Regardless of your current level of leadership experience, you're passionate about supporting your staff and wider colleagues' development, as well as driving your own personal development and maximising your team's and individual contribution to drug discovery.


You also have:

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PhD, or equivalent, in bioinformatics, mathematics, computer science, statistics, engineering or the life sciences
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Expertise in omics, particularly NGS based technologies
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Expertise in biostatistics including Frequentist statistics, Bayesian statistics and Design of Experiments
*

In-depth experience with drug discovery and AZ R&D disease area priorities and proven experience with impacting drug discovery projects across multiple disease areas.
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In-depth experience with delivering statistical solutions to early drug discovery
*

In-depth experience of manipulating and analysing large high dimensionality unstructured datasets, drawing conclusions, defining recommended actions, and reporting results across stakeholders
*

Excellent written and verbal communication, business analysis, and consultancy skills
*

Experience in a complex global organization
*

A track record of people leadership



Desirable for the role

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Comfortable working in high performance computing or cloud environment
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Proven track record of publishing relevant results and tools in peer-reviewed journals, conferences, and other scientific proceedings.
*

Experience in novel methods development and application
*

Experience in influencing and controlling budgets



The successful candidate can operate effectively in a multi-disciplinary research environment. You enjoy teamwork, have a collaborative nature and will be an encouraging colleague to all.

What's next?
If this sound like the position and place for you - apply today!
We look forward to receiving your application, but no later than May 11, 2025. The interview process will be ongoing, do not hesitate to apply early.

More information:
For more information about the position please contact the hiring manager Natalie van Zuydam, [email protected]

Additional information
Our Gothenburg site: https://www.astrazeneca.com/our-science/gothenburg.html
Life in Gothenburg: https://www.movetogothenburg.com/
About AstraZeneca R&D: https://www.astrazeneca.com/r-d.html Visa mindre

The University of Gothenburg tackles society’s challenges with diverse knowledge. 56 000 students and 6 600 employees make the university a large and inspiring place to work and study. Strong research and attractive study programmes attract researchers and students from around the world. With new knowledge and new perspectives, the University contributes to a better future.The Institute of Biomedicine is involved in both research and education. In both of these areas, we focus on fundamental knowledge of the living cell – what it consists of, how it works, how its function is directed by the genetic material, and how it interacts with various kinds of micro-organisms. Using this knowledge, we try to elucidate the causes of diseases, and find new ways to diagnose and treat them.

The Institute is composed of the following four departments:


• The Department of Infectious Diseases
• The Department of Microbiology and Immunology
• The Department of Medical Biochemistry and Cell Biology
• The Department of Laboratory Medicine

At present, the institute has about 340 employees and approximately 450 million SEK in total asset.

Duties 
We are looking for someone with expertise in the latest state-of-the-art solutions in AI applied to pathology. In the role of research assistant, you will lead the implementation and optimization of both proprietary and existing AI solutions for image analysis in pathology. You will be involved in the entire development cycle, from concept to implementation.

The primary tools for this work include Python and specific libraries such as Pytorch, Tensorflow, and OpenSlide. You are expected to write robust and performance-optimized code that aligns with the latest advancements in the field.

Responsibilities also encompass ensuring that implemented AI models run in a container-based environment. This involves configuring and optimizing the environment for seamless operation and accessibility. You are expected to drive and optimize AI models using GPUs to ensure high performance and efficient processing of large datasets in pathology.

Qualifications 
Masters degree in relevant subject or at least 75% credits

Experience in development of AI solutions for digital pathology

Employment 
The employment is part time 20% and temporary, 11 months, with placement at the Institute of Biomedicine. First day of employment as agreed. 

Contact information for the post 
If you have any questions about the position, please contact Associate professor, Group leader: Noora Neittaanmäki Email: [email protected] Phone: 0727190367

Unions 
Union representatives at the University of Gothenburg can be found here:?https://www.gu.se/om-universitetet/jobba-hos-oss/hjalp-for-sokande 

Application 
To apply for a position at the University of Gothenburg, you have to create an account in our recruitment system. Submit your application via the University of Gothenburg’s recruitment portal by clicking the “Apply” button. It is your responsibility to ensure that the application is complete as per the vacancy notice, and that the University receives it by the final application deadline. 

Applications must be received by: 2025-05-16

The University works actively to achieve a working environment with equal conditions, and values the qualities that diversity brings to its operations.

Salaries are set individually at the University.

In accordance with the National Archives of Sweden’s regulations, the University must archive application documents for two years after the appointment is filled. If you request that your documents are returned, they will be returned to you once the two years have passed. Otherwise, they will be destroyed.

In connection to this recruitment, we have already decided which recruitment channels we should use. We therefore decline further contact with vendors, recruitment and staffing companies. Visa mindre

The University of Gothenburg tackles society’s challenges with diverse knowledge. 56 000 students and 6 600 employees make the university a large and inspiring place to work and study. Strong research and attractive study programmes attract researchers and students from around the world. With new knowledge and new perspectives, the University contributes to a better future.The Institute of Biomedicine is involved in both research and education. In both of these areas, we focus on fundamental knowledge of the living cell – what it consists of, how it works, how its function is directed by the genetic material, and how it interacts with various kinds of micro-organisms. Using this knowledge, we try to elucidate the causes of diseases, and find new ways to diagnose and treat them. At present, the institute has about 360 employees and approximately 450 million SEK in total assets.

Subject area 
Single-cell Genomics of Human Development

Subject area description 
The overall goal of this project is to bridge current in vitro models of human embryonic development with the latest progress in developmental hematopoiesis studied in vivo. This will lead to new frameworks for defining the prenatal transformation events leading to childhood cancer.

We harness single-cell genomics, and advanced experimental models to chart the mammalian developmental processes modelled during in vitro stem cell differentiation. Specifically, we are interested in the variety of molecular programmes underlying the emergence of hematopoietic cells at multiple anatomical locations and timepoints in the developing embryo, and into what extent these are reproduced in the dish.

Duties 
The selected candidate will be working in a cross-disciplinary team, and will apply computational biology approaches to analyse high-throughput next generation sequencing data for uncovering novel drivers of mammalian embryonic development. The selected candidate will be expected to contribute to co-supervision of younger colleagues, to manuscript writing and will be expected to present their work regularly at group and department meetings.

Eligibility 
The eligibility criteria for employing teaching staff are set out in Chapter 4 of the Higher Education Ordinance and in the Appointment Procedure for Teaching Posts at the University of Gothenburg. 

To be eligible for appointment as a postdoc, the applicant is required to have a doctoral degree, a doctoral degree in art or a foreign degree that is deemed to be equivalent to a doctoral degree. This eligibility requirement must be met before the employment decision is made. 

In the first instance, those who have completed their degree no more than three years prior to the end of the application period shall be considered. Those who have completed their degree more than three years prior to the end of the application period may also be considered in the first instance if special grounds exist. Special grounds relate to leave of absence due to illness, parental leave, commissions of trust within union organisations, service within the defence services or other similar circumstances, as well as clinical service or service/assignment relevant to the subject area. 

Assessment criteria 
The candidate selection will be based on the cover letter, Curriculum Vitae, interview and contact with references.

Specific selection criteria:

1 – Prior hands-on experience with R and/or Python language, bash shell environment, high performance computing, next-generation sequencing data analysis, and single-cell analysis workflows

2 – Communication and team work skills

3 – Interest and theoretical background in stem cells and developmental biology and hematology

4 – Interest in the development and implementation of novel computational workflows to uncover novel biology.

Regulations for the evaluation of qualifications for academic positions are given in Chapter 4, Section 3 - 4 of the Higher Education Ordinance.

Employment 
The employment is full time and temporary, two years with the possibility of one year's extension, with placement at the Institute of Biomedicine. First day of employment as agreed.

Selection process 
How to apply for a position | University of Gothenburg

Contact information 
If you have any questions about the position, please contact Carolina Guibentif, Researcher, +46 702253076, [email protected]

Unions 
Union representatives at the University of Gothenburg can be found here:?https://www.gu.se/om-universitetet/jobba-hos-oss/hjalp-for-sokande 

Application 

Submit your application via the University of Gothenburg’s recruitment portal by clicking the “Apply” button. It is your responsibility to ensure that the application is complete as per the vacancy notice, and that the University receives it by the final application deadline.  

The application should contain:

- A cover letter giving a brief description of previous research experience, and a motivation to why you are applying

- A CV including a list of publications

- Contact details of two references

- Proof of completed PhD

Applications must be received by: 2025-05-06

Information for International Applicants 

Choosing a career in a foreign country is a big step. Thus, to give you a general idea of what we and Gothenburg have to offer in terms of benefits and life in general for you and your family/spouse/partner please visit: 

https://www.gu.se/en/about-the-university/welcome-services 
https://www.movetogothenburg.com/ 

The University works actively to achieve a working environment with equal conditions, and values the qualities that diversity brings to its operations.

Salaries are set individually at the University.

In accordance with the National Archives of Sweden’s regulations, the University must archive application documents for two years after the appointment is filled. If you request that your documents are returned, they will be returned to you once the two years have passed. Otherwise, they will be destroyed.

In connection to this recruitment, we have already decided which recruitment channels we should use. We therefore decline further contact with vendors, recruitment and staffing companies. Visa mindre

Do you have extensive Drug Metabolism and Pharmacokinetic (DMPK) expertise with a background in medicinal chemistry, pharmacy, pharmaceutical science and/or drug discovery, and would you like to apply your expertise in a global company that follows the science and turns ideas into life-changing medicines? Then you could be the new colleague we are looking for!

We are now seeking an experienced and motivated individual to join the team as a Preclinical DMPK Project Leader (Senior Scientist/Associate Principal Scientist/Principal Scientist, depending on your level of professional experience), preferably with experience across multiple modalities.


At AstraZeneca Respiratory & Immunology, we're proud to have an outstanding workplace culture that encourages innovation and teamwork. We are united by our vision to push the boundaries of DMPK science to transform ideas into medicines for R&I patients. Employees are empowered to express diverse perspectives - and are made to feel valued, energized and rewarded for their ideas and creativity.

What you'll do:
In the role you would work collaboratively with discovery project representatives from other disciplines including medicinal chemistry, biology, safety and pharmaceutical sciences. You will influence drug design and optimization of ADMET (absorption, distribution, metabolism, excretion, toxicity) properties. Hence, it is your responsibility to ensure delivery of all DMPK related activities, including in vitro ADME, biotransformation, bioanalysis, preclinical PK and PD underpinning human dose prediction to early drug projects from target selection to candidate drug selection. We believe that you have a solid understanding of DMPK and chemistry and that you will be able to provide expert advice and interpretation of complex drug discovery data.

Main Duties and Responsibilities
* Responsible for leading all DMPK related activities, including coordinating and engaging with internal and external DMPK colleagues and collaborators, on project related activities. Deliver DMPK input and data to projects within agreed timelines and to the right quality to ensure that DMPK challenges are thoroughly assessed and resolved.
* Contribute to the design of preclinical in vivo studies to answer crucial project questions.
* Accountable, together with other functions such as Medicinal Chemistry, Bioscience and Safety, for compound design and effective cross-discipline optimization. Apply an understanding of DMPK and PKPD to support/influence project progression and strategy as well as providing the framework for human dose predictions.
* Prepare clear presentations related to the above for internal governance interactions

Essential requirements:
* PhD in Medicinal, Organic or Physical Chemistry or bio-pharmaceutics/pharmacokinetics or equivalent experience in a relevant field
* Formal training or proven experience of working with pharmacokinetics and drug metabolism and a good understanding of pharmacodynamics
* Understanding of correlations between physicochemical characteristics and their influence on DMPK properties and subsequent design of new compounds
* Have (at least) basic PK modelling skills, experience of human dose and PK prediction as well as understanding of disease biology and linking to PKPD understanding
* Extensive experience (5+ years) of working in preclinical DMPK
* Experience from drug discovery, cross-functional working and compound/project progression
* Ability to engage and collaborate across boundaries with a problem solving attitude and focus on delivery
* Strong communication skills



Why AstraZeneca?
At AstraZeneca we're dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There's no better place to make a difference to medicine, patients and society. An inclusive culture that champions diversity and collaboration. Always committed to lifelong learning, growth and development



What's next?
This is an exciting opportunity for a talented DMPK scientist to join a strong, dynamic team and support the portfolio of a major pharmaceutical company that has science at its heart whilst being based in the beautiful city of Gothenburg, Sweden. If you are ready to make a difference - apply today and together we will make it happen! We welcome your application until April 30, 2025.


Find Out More:

Life at AstraZeneca

This is what we're made of

Relocate to Gothenburg Visa mindre

Are you an experienced drug discovery scientist with expertise in pharmacokinetics, pharmacology and drug metabolism (DMPK)? Would you like to apply your expertise in a global company that follows the science and turn ideas into life changing medicines? Then you could be the new colleague we are looking for!



We are now looking for an experienced and motivated individual to join the team as a DMPK Project Leader. The position is placed at AstraZeneca's dynamic R&D site in Gothenburg, Sweden. Working at AstraZeneca means being entrepreneurial, following the science, scrutinizing data and details simultaneously with holistic thinking and through teamwork make progress. Your level of professional experience will be relevant for your initial career level (Associate Principal Scientist or Principal Scientist).



Respiratory & Immunology (R&I) is one of the three main therapeutic research areas within AstraZeneca. Early R&I is a global function, with research units in Gaithersburg (US), Cambridge (UK) and Gothenburg (Sweden), and delivers candidate drugs into late-stage clinical development. DMPK interacts with other functions in supporting Early R&I projects all along the value chain, from target selection all the way to market launch and Life cycle management.



What you'll do:
With a true passion for drug discovery you will support our portfolio within the R&I therapeutic area. In the DMPK project lead role you will work collaboratively with project representatives from other disciplines. These may include biology, antibody Discovery/Protein Engineering, medicinal chemistry, safety, clinical pharmacology, and pharmaceutical sciences, where your task is to influence candidate profiling by providing the necessary DMPK support for clinical investigations.



It is your responsibility to ensure delivery of all DMPK related activities. These include preclinical PK experiments, in vitro ADME and biotransformation to yield pharmacokinetic understanding. Furthermore, assisting design of pharmacodynamic studies that ultimately delivers a pharmacological assessment underpinning human dose prediction.



You will work on projects from candidate selection to Phase 2a. We believe that you have a solid understanding of DMPK, a working knowledge of pharmacology, and that you will be able to provide expert advice and interpretation of complex drug discovery data.



Main Duties and Responsibilities
* Communicate scientific progresses both externally and internally
* Deliver DMPK input and data to projects within agreed timelines and to the right quality
* Apply an understanding of DMPK to support/influence compound profiling, project progression and project strategy
* Define and deliver a translational quantitative PKPD strategy in projects, so that effective conclusions can be made
* Contribute to estimation of safety margins and report results and interpretations to project teams and internal governance bodies
* Responsible for leading, coordinating and engaging with R&I DMPK colleagues in project related activities
* Prepare clear presentations related to the above for internal governance bodies

Essential requirements:
* PhD or equivalent experience in a relevant field
* Expert in DMPK sciences with profound knowledge of drug discovery and development processes
* Broad experience across different modalities (small molecules & biologics) drug development (PK & Bioanalysis)
* Experience with regulatory submissions for biologics and small molecules
* Good knowledge of all DMPK assays including the use of in silico tools for PK prediction
* Experience in project leadership
* Collaborative mindset
* Team player
* Proactive and good communication skills

Why AstraZeneca?
At AstraZeneca we're dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There's no better place to make a difference to medicine, patients and society. An inclusive culture that champions diversity and collaboration. Always committed to lifelong learning, growth and development.

Work policy:
When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working give us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

What's next!
If you are ready to make a difference - apply today, and we'll make it happen together! We welcome your application until April 30, 2025.

Where can I find out more?

Life at AstraZeneca

This is what we're made of

Relocate to Gothenburg Visa mindre

Göteborgs universitet möter samhällets utmaningar med mångsidig kunskap. 56 000 studenter och 6 600 medarbetare gör universitetet till en stor och inspirerande arbetsplats. Stark forskning och attraktiva utbildningar lockar forskare och studenter från hela världen. Med ny kunskap och nya perspektiv bidrar Göteborgs universitet till en bättre framtid.Vid Institutionen för neurovetenskap och fysiologi vid Sahlgrenska akademin bedrivs omfattande forskning och undervisning över stora kunskapsområden - från molekyl till människa. Verksamheten utgörs av fem sektioner; farmakologi, fysiologi, hälsa och rehabilitering, klinisk neurovetenskap samt psykiatri och neurokemi.

Institutionen för neurovetenskap och fysiologi, söker nu en forskare, med placering vid Sektionen för farmakologi.

Anställningen ligger vid enheten för farmakokinetik och läkemedelsmetabolism. Forskningen vid enheten spänner från mekanistiska studier av farmakokinetiska och farmakodynamiska processer på cellulär och molekylär nivå, till studier av läkemedels omsättning i kroppen som grund för rationell behandling av olika patientpopulationer. Särskilda fokusområden är nya läkemedelsmodaliteters omsättning och funktion, och datorbaserad modellering av dessa processer och hur de påverkas av den kemiska strukturen hos läkemedelsmolekylen, vilket exempelvis studeras genom molekyldynamiska simuleringstekniker. Grupperingen har starka band till forskande läkemedelsindustri och har en central roll i den nationella infrastrukturen för terapeutiska oligonukleotider, OligoNova. För mer information om verksamheten vid enheten, se avdelningens hemsida https://www.gu.se/en/research/cellular-and-molecular-pharmacokinetics  

Arbetsuppgifter

Du kommer att utföra forskning och handleda studentarbeten inom området molekylär farmakokinetisk simulering. Dessutom kommer du att undervisa vid enhetens kurser, främst inom apotekar- och receptarieprogrammen, i ämnen som farmakokinetik, farmakodynamik, toxikologi och läkemedelsutveckling.

Kvalifikationer

För att vara kvalificerad för denna tjänst krävs en doktorsexamen i farmaceutiska vetenskaper eller ett närliggande ämne. Du måste ha erfarenhet av forskning och undervisning inom farmakokinetik eller ett ämne som bedöms som motsvarande. Praktisk kunskap i molekylära datorsimuleringstekniker är meriterande. Vi lägger stor vikt vid personlig lämplighet. 

Anställning

Anställningen är en tidsbegränsad anställning i 11 månader, 100% av heltid, med placering tills vidare vid Institutionen för neurovetenskap och fysiologi. Tillträde: snarast eller enligt överenskommelse. 

Kontaktuppgifter för anställningen

Har du frågor om anställningen är du välkommen att kontakta professor Pär Matsson, tfn: +46 31 786 49 32, e-post: [email protected]

Ansvarig chef är professor/sektionschef Michael Winder, tfn: +46 31 786 34 77, e-post: [email protected]

Ansökningshandlingar skickas inte till kontaktpersonerna.

Fackliga organisationer

Fackliga företrädare vid Göteborgs universitet hittar du här: https://www.gu.se/om-universitetet/jobba-hos-oss/hjalp-for-sokande

Ansökan

Du söker anställningen via Göteborgs universitets rekryteringsportal genom att registrera din ansökan elektroniskt via hemsidan: https://www.gu.se/om-universitetet/jobba-hos-oss/lediga-anstallningar 

Du som sökande ansvarar för att ansökan är komplett i enlighet med annonsen och att den är universitetet tillhanda senast sista ansökningsdag.

Till ansökan skall bifogas Curriculum Vitae inklusive publikationslista och intyg om doktorsexamen.

Ansökan ska vara inkommen senast: 2025-04-29

Universitetet arbetar aktivt för en arbetsmiljö med jämställda förhållanden och sätter värde på de kvalitéer mångfald tillför verksamheten.

Universitetet tillämpar individuell lönesättning.

Enligt Riksarkivets föreskrifter är universitetet skyldigt att förvara ansökningshandlingar i två år efter tillsättningsbeslutet. Om du som sökande till en anställning särskilt begär tillbaka dina handlingar återsänds de när de två åren har förflutit, i annat fall kommer de att gallras ut.

Till bemannings- och rekryteringsföretag och till dig som är försäljare: Göteborgs universitet anlitar upphandlad annonsbyrå i samband med rekrytering av personal. Vi undanber oss vänligen men bestämt direktkontakt med bemannings- och rekryteringsföretag samt försäljare av jobbannonser. Visa mindre

Are you a motivated Bioinformatician with a strong analytical mindset? We are looking for individuals who are eager to leverage their computational skills to help us advance our approaches for in-silico drug target identification and validation. Is that you? If your answer is yes, we invite you to join us on our mission to develop novel medicines and improve the lives of millions worldwide!


We are looking for a Senior Data Scientist to join our team at our vibrant AstraZeneca R&D site in Gothenburg, Sweden. This position is located within the Data Sciences & Quantitative Biology department - a global, diverse and delivery focused department where we collaborate to support drug projects striving to impact patients' lives. The role is on-site in Gothenburg, Sweden and will not have the ability to be located remotely.

We are a diverse team of computational scientists from various backgrounds, representing over five nationalities and speaking more than ten languages. We pride ourselves on fostering an inclusive and collaborative work environment where innovation thrives, and diverse perspectives are valued. Our team is dedicated to continuous learning and scientific excellence, with a strong focus on next-generation sequencing (NGS) omics as our key technology.

Our mission is to advance patient care by gaining insights into human biology and facilitating the discovery of new therapeutics. This involves supporting the identification of novel drug targets and prioritizing targets within our drug discovery portfolio by delivering data analysis solutions for high-dimensional biological datasets.

What you'll do?
As a Senior Data Scientist you will be working in equal parts on capability development and project delivery. In other words, you'll be instrumental in both building data analysis pipelines, as well as to utilize these tools to help answer critical questions in drug discovery projects.

You will be empowered and encouraged to engage with your stakeholders and collaborators independently to ensure timely and accurate delivery to running projects, advise on experiment design and technological choices and interpretation of results.

Typical job accountabilities will include:
* Work in close collaboration with wet-lab scientists that are designing the experiments, sequencing facility and fellow bioinformaticians across the company to develop innovative data science approaches
* Maintain, extend, and further refine our analytical pipelines, as well as supporting ongoing projects with your computational expertise and domain knowledge
* Facilitate effective communication across diverse project teams, including wet-lab scientists and computational biologists, ensuring clear dissemination of your findings
* Foster scientific innovation and excellence by developing robust software and processes, following the advancements in literature and identify opportunities for improvement
* Ensure your work is efficiently communicated, well-documented, maintained, and shared or published when appropriate

Essential requirements
We are looking for a skilled bioinformatician with a proven track record of delivering analytical solutions in business or academic setting, ideally both. Your ability to transform detailed requests into comprehensive insights through collaboration with colleagues, partners, and stakeholders will be crucial.



* A PhD or equivalent research experience in Bioinformatics, Genetics, Computer Science, or a Biology/Medicine degree with a strong focus on data analysis

* Knowledge of human genetics and cell biology, ideally within a disease context

* Experience working with data from biological assays and in vivo/in vitro model systems

* A deep understanding of CRISPR technology and its applications in drug discovery

* A strong publication track record demonstrating expertise in data analysis, management, and visualization in one or more of the following areas: RNA or DNA-based omics, multivariate/high-dimensional omics integration, single-cell technologies, epigenomics, or metagenomics

* Proficiency in Python (including the Pandas and NumPy stack) and R (incl Bioconductor, and Rmarkdown), and related coding tools, along with knowledge of best practices for code structuring, documentation, and versioning using Git/GitHub

* Experience working in a Linux/Unix environment, including shell scripting and standard command-line tools

* A proactive professional approach with a curiosity for advances in research advances and a willingness to learn new skills and explore new fields



Desirable requirements
* Experience working in a pre-clinical drug discovery environment within the pharmaceutical or biotech industry
* Experience with Python (including the Pandas and NumPy stack) or a similar programming language (e.g., C++, Rust)
* Familiarity with conda and tools for reproducible research like Snakemake or Nextflow
* Familiarity with high-performance computing (HPC) systems and their applications in data-intensive research





What's next?
Are you ready to make a difference? Apply now to join our team! We look forward to receiving your application (including CV and cover letter) no later than April 13, 2025.



Additional information
Our Gothenburg site: https://www.astrazeneca.com/our-science/gothenburg.html
Life in Gothenburg: https://www.movetogothenburg.com/
Make a move to Global Gothenburg: https://www.youtube.com/watch?v=c-Iqbb4aw38
About BioPharmaceuticals R&D: https://www.astrazeneca.com/r-d.html Visa mindre

Are you passionate about patient safety and always looking for quality and compliance excellence and opportunities for continuous process improvement? If you a true believer of the relevance of having robust processes and oversight in place for the ultimate goal of providing medicines with optimal benefit/risk balance to patients, this opportunity is for you!

At AstraZeneca, we put patients first and strive to meet their unmet needs worldwide. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you're our kind of person.

Join us in the QPPV Office team as a Director Patient Safety Excellence. Help us reach our goal of having the best possible pharmacovigilance system. This is an excellent chance to be part of a global high-performing and influential team working in a true collaborative environment.

This role will be based at our Gothenburg site, one of AstraZeneca's three strategic science centers. We thrive in a multinational environment working cross-functionally across the globe with AstraZeneca colleagues as well as academic and industry partners. Our way of life is to foster a working environment that nurtures, collaboration, openness and innovation. Therefore, we have created space for meetings, socializing and relaxation, where spontaneous meetings can give birth to new innovations. The unexpected ideas or thoughts that can come from a chat over something as simple as a cup of coffee or a stroll on our "walk and talk" meeting trail.

At AstraZeneca, Global Patient Safety (GPS) is at the forefront of defining and optimizing the safety profile of our medicines across their lifecycle in all therapeutic areas. GPS leads the way in integrating science, data, and technology to shape clinical safety strategies. From monitoring and detection to characterization and reporting of adverse events, GPS plays a critical role in ensuring the safety of our medicines for patients worldwide. The QPPV Office is a central part of GPS driving gold standard pharmacovigilance quality, compliance and efficiency across AstraZeneca.



What you'll do
You will be acting as Pharmacovigilance senior expert continually strengthen the QPPV reach and influence internally and externally, thus driving gold standard pharmacovigilance quality, compliance and efficiency across AstraZeneca. You will be supporting the QPPV in triaging topics that require awareness, assessment and decision making for processes for which you will become main point of contact toward business process owners, patient safety teams and representatives from other function. You will lead and drive continuous improvement projects relevant to the scope of the QPPV function. You will be managing additional tasks relevant to the QPPV role and responsibilities as per existing and upcoming regulatory requirements and internal needs which includes training, compliance and PSMF related activities. You will be as needed required to support audit and inspections activities.

Essential for the role

* Life science degree (MD, PharmD, RPh, RN, or related degree) or master's degree in life sciences, or related field

* Extensive experience in patient safety/pharmacovigilance including applicable industry experience and seen as a subject matter expert

* Good knowledge and comprehension of relevant pharmacovigilance legislation

* Excellent medical writing and communication skills

* Experience and ability to develop and implement new standards and best practices

* Strong project management skills

* Proven ability to lead teams and collaborate in a continuous improvement
* Good strategic thinking capability

Desirable for the role

* Regulatory strategy knowledge and experience

* Clinical development knowledge and experience

* Lean Sigma experience

Why AstraZeneca?
When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

Build unrivalled capabilities in a place that promotes learning and agility and offers development opportunities. We never stand still. You'll have the chance to grow your abilities, skills, and knowledge constantly. Here we are a fusion of challenging and exciting work in an energizing and inspiring environment.

Embrace the opportunity for development - whether it's upskilling or reskilling. We are a high-performing learning organization with autonomy over how we learn. We deliver innovative development experiences that sustain and grow future leaders and talent. Because we want all our people to embrace the challenges and opportunities ahead. This is the place to build a fulfilling, long-term career.

Ready to make a difference? Apply now! Visa mindre

Are you ready to make a significant impact in the world of drug development?

This is an excellent time to join a team of clinical researchers, clinical scientists and physicians who are translating scientific discoveries into early phase clinical development plans and clinical studies across a wide range of diseases.

The position as Director, Early Clinical Research is placed at AstraZeneca's vibrant R&D site in Gothenburg, Sweden where you will be part of an international, open-minded and creative working atmosphere based on collaboration and innovation.

Who We Are

In the Respiratory and Immunology Early Clinical Development team, we are investigating the drivers of key respiratory and immunology diseases, with access to pioneering science, innovative drug discovery approaches and key collaborations with academic centers around the world. We are investigating a wide range of drug modalities - small molecules, biologics, oligonucleotides and cell therapies - across multiple diseases with high unmet medical need.

Early Clinical Development in R&I is where science meets clinical drug development with a focus upon delivering innovative, early phase clinical studies (Phase 1 - Phase 2), while collaborating closely with our late phase clinical development colleagues who guide our phase 3 clinical studies. We are a diverse team of experienced physicians and clinical scientists who collaborate with scientists and translational medicine colleagues to define our early phase clinical development strategies, design innovative Phase 1-2 clinical trials, develop and validate new clinical endpoints and translate scientific ideas to proof-of-concept studies in targeted patient populations.



What You Will Do

You will contribute to early Phase I-2 global clinical trials and related clinical research projects for compounds that are targeting immunology indications ranging from SLE and RA to IBD, as well as serving as an expert on the design, conduct, monitoring, data interpretation, and reporting of these studies. Additionally, you will work on cross-functional teams within our ECD group and across the broader early R&I organization that are framing our strategies and development plans for compounds that are being developed for a range of indications, including asthma, COPD and additional immunology indications.

You will contribute to the clinical development of molecules in cross-functional teams to support early phase clinical development activities. These activities include supporting the creation of overall clinical development plans and clinical study design and contributing to the writing of clinical study protocols, key study and health authority documentation, medical monitoring and ensuring timely delivery of studies, all in collaboration with relevant internal and external partners and clinical research organizations.

Qualifications that apply to the role:

* Advanced degree in relevant scientific subject area (PhD, MD, or PharmD). Experience in gastroenterology / inflammatory bowel disease and/or research training in immunology or cell therapy is a plus.
* Minimum of 2 years of experience in early phase clinical development. Experience in the design, delivery and interpretation of Ph1 / Ph2 studies in relevant non-oncology indications is a plus.
* Experience in the authoring of relevant regulatory documents, including INDs, protocols, ICFs, PIPs, briefing books as well authoring responses to HAs / ECs and site queries is desirable
* An understanding of the entire drug development process, including clinical and non-clinical study design and execution, and clinical research methodology and biostatistics principles, to facilitate innovative and efficient clinical trial design, and clinical development plans with clear data-driven decision rules.
* An understanding of FDA, MHRA and ICH GCP guidelines to ensure the appropriate conduct of global clinical studies.
* Attention to detail, internal drive to generate high-quality work and sense of passion and urgency to achieve team and program goals.
* Demonstrated experience managing complex projects and working collaboratively with multiple stakeholders.
* Outstanding communication skills.
* Excellent analytical, problem solving and strategic planning skills.
* Ability to thrive in a fast-paced environment.



So, What's Next?

Please send in your application in English, including your CV and cover letter, no later than March 31st.



Where can I find out more?

AstraZeneca Gothenburg site: https://www.astrazeneca.com/our-company/our-locations/gothenburg.html

Life in Gothenburg: https://www.astrazeneca.se/om-oss/verksamheten-i-sverige/goteborg/relocate-to-gothenburg.htm
R&I at AstraZeneca: https://www.astrazeneca.com/our-therapy-areas/respiratory-and-immunology.html

Why AstraZeneca?

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

At AstraZeneca, we are dedicated to being a Great Place to Work. Our team is inclusive and diverse, working in a solution-oriented, trusting, and collaborative work environment. We are committed to improving healthcare and quality of life for patients across a wide range of diseases and disorders by developing innovative therapies. Join us in the Biopharmaceuticals R&D department and contribute to our growing pipeline! Visa mindre

AstraZeneca is a major international healthcare business engaged in the research, development, manufacture and marketing of prescription pharmaceuticals and the supply of healthcare services. AstraZeneca is proud to offer a unique workplace culture that inspires innovation and collaboration. Co-workers are empowered to express diverse perspectives - and are made to feel valued, energized and rewarded for their ideas and creativity. The arena Are you interested in a challenging opportunity within the Development Quality function in one of the world’s leading pharmaceutical companies? The Development Quality function is responsible for quality oversight of the pharmaceutical development activities within AstraZeneca. We are now looking for a Quality Advisor with GMP focus to our Gothenburg team. AstraZeneca’s pharmaceutical development organizations manage all facets of the process of turning a molecule into a medicine which can be safely and effectively used by patients. The Quality Advisor role has a broad range of responsibilities to ensure all internal and external requirements are fulfilled for the AstraZeneca projects in the development phase We have an exciting opportunity for a 12 months temporary assignment as Quality Advisor, in the Site Quality Gothenburg team, who’ll be the prime source for quality & compliance advice and providing quality support to the science functions and throughout the drug development process chains. This is a great opportunity for you who are strong in quality and like to work close to development, Good Manufacturing Practice and making sure quality is assured when delivering new products The role Working in the Site Quality team means you will work closely with the internal assets/facilities, teaming up with the pharmaceutical development functions and be involved in cross business processes. To build strong relationships with these functions knowing their business is key, to give support to projects and develop ways of working that builds for success. The ability to interpret and trend compliance data to measure and improve quality standards is key. You will develop and maintain a knowledge of the quality regulations and guidelines applicable to your area and a deep scientific understanding of the products that you are supporting. Whilst taking on your own specialist areas and making good quality decisions, you will be encouraged to think strategically and use your problem solving skills to resolve any quality issues. You will participate and contribute to continuous improvement projects with the aim to standardize and simplify our internal processes. Typical Accountabilities: • Responsible for quality release of manufactured Drug Product, Investigational Medicinal Product for clinical trials • Support the pharmaceutical development functions with investigations of deviations, changes and other quality and compliance decisions in the development projects related to drug product • Providing proactive quality advice to support the development, implementation and continuous improvement of GMP quality systems across the Clinical Supply functions and support implementation of agreed global standards • Operate as part of a global organisation with an integrated mindset to create an organisation with common processes and ways of working Minimum requirements – Education and Experience • MSc in pharmacy or engineering (specializing in Pharmaceuticals) with at least 3 years’ experience of working within a pharmaceutical GMP environment • Demonstrates understanding of international quality systems regulations, concepts, industry practices to adopt best in class processes • A comprehensive understanding of GMP regulations, the pharmaceutical development process and supply chain process would be advantageous • Experience of interacting effectively across interfaces collaborating internally in a good communicative way • Fluent in written and spoken English Required soft skills: • Ability to work in a fast-paced environment, meet deadlines, and balance multiple priorities. Independently motivated, detail-oriented, and “can-do” attitude • Excellent team working and networking skills and encourages team effectiveness • A good communicator with experience of interacting effectively across interfaces collaborating internally About AstraZeneca Gothenburg Hub Our stunning campus in Gothenburg is one of AstraZeneca’s three strategic science centers. The site is home to over 2,500 employees, from 50 different nationalities. Gothenburg includes the complete range of functions, and as such offers plenty of development opportunities for a wide range of professionals. Our science teams in Gothenburg collaborate with academic and industry partners in Sweden and globally. And the site itself has been designed with collaboration in mind. From the Coffee Lab to exercise areas, we’ve built a series of environments where innovation can happen.
This is a consultancy assignment at AstraZeneca, and during the assignment, you will be employed by Logent. Visa mindre

AstraZeneca is a major international healthcare business engaged in the research, development, manufacture and marketing of prescription pharmaceuticals and the supply of healthcare services. AstraZeneca is proud to offer a unique workplace culture that inspires innovation and collaboration. Co-workers are empowered to express diverse perspectives - and are made to feel valued, energized and rewarded for their ideas and creativity. Inhalation Product Development (IPD) at AstraZeneca is a multinational organization that combines decades of experience in inhalation technology whether it is nebulization, pMDI or DPI. Our vision is to develop and provide to patients best-in-class, innovative and sustainable products to deliver medicine via inhalation. We are now seeking an Analytical Scientist to join our dynamic Analytical Sciences team, focusing on the characterization of inhaled molecules within Inhalation Product Development in Gothenburg. This is a unique opportunity to play a pivotal role in the development of inhaled products for AstraZeneca. You will be part of a highly collaborative team of analytical experts within the inhalation area, contributing to analytical development and characterization of inhaled products. This job includes lab-based responsibilities, where you are expected to work collaboratively with colleagues in daily analytical deliveries, documenting your experiments carefully and to the right quality, utilizing both manual and automated analytical techniques to develop and deliver innovative inhaled medicines to patients. To be successful in this role you will need an analytical background combined with excellent communication skills and the ability to engage and collaborate cross-functionally. We are looking for a candidate that possesses a fair understanding of the overall drug development process and has an enthusiasm for laboratory-based work as well as solving technical challenges and problems. Essential qualifications for the role: - BSc or MSc degree in Analytical Chemistry or other relevant scientific discipline (Biochemistry, Biotechnology..). - Scientific knowledge within analytical sciences and technically skilled with analytical separation techniques such as liquid chromatography (UPLC). - Strong scientific interest and ambition to develop yourself in the analytical sciences area as well as leaning analytical techniques used for inhaled products. - Understanding the principles and applications of GMP is essential and Experience of working in a GMP environment would be desirable - Excellent communication skills in English, both oral and written. Desirable skills - Experience in aerosol characterization techniques used for inhaled products, such as impactor analysis. - Experience with method development and validation. - Experience with solving technical challenges and problems. - Experience of analysis of small molecules. AstraZeneca is one of the world’s most exciting bio-pharmaceutical companies. From scientists to sales, lab techs to legal, we’re on a mission to turn ideas into life-changing medicines that improve patients’ lives and benefit society. We need great people who share our passion for science and have the drive and determination to meet the unmet needs of patients around the world. This is a consultancy assignment, and during the assignment, you will be employed by Logent. Visa mindre

Join us in our Site Quality Team! We provide Quality oversight in the development of Investigational products and have the responsibility for Licence to Operate at our development site and play an important part in the commercialisation of new medicines. Development Quality is a Global group, with teams located in Gothenburg (Sweden), Macclesfield, (UK) and Durham (North Carolina, US). With a portfolio encompassing both small and large molecules, combination products and ground breaking technologies you will be a part of providing novel life-changing medicines to our patients around the globe. Are you ready to take the lead in ensuring patient safety and maintaining License to Operate across our Development functions? As an Associate Director in Site Quality, you will be the prime source for quality/compliance advise in validation activities and provide quality leadership to Development functions. You will interpret AZ regulatory and GMP standards into appropriate quality standards and provide guidance to ensure AstraZeneca and Regulatory requirements are met. The role requires independent operation, risk management and lean skills, and decision-making against a background of varying regulations and standards. Your responsibility will extend to internal assets and GMP compliance decisions, having a major impact on AZ’s business. Your role As an Associate Director, you will develop and maintain in-depth knowledge of the quality regulations and guidelines applicable to your area. You will mentor and support junior colleagues, build strong customer relationships, and participate in GxP audits/initiatives. You will also be responsible for developing and approving GMP documentation and QA risk assessments, providing Quality input into business improvement projects, and be part of external Regulatory Authority GMP inspections. You will work closely with the leadership teams of our customers to set strategic direction for quality within that area, maintaining quality oversight and driving continuous improvement. Most appreciated in the role is the ability to lead projects, to improve processes or ways of working and support different functions with your subject matter expert knowledge. Working in a development environment makes your role versified and enables lifelong learning in everyday tasks. Essential for the role: • Appropriate scientific degree with extensive experience (5-10 years) of working with validation, in a pharmaceutical GMP environment, preferably within a pharmaceutical development organization • Extensive experience from working with all types of validation including, equipment, automation and IT system. • A broad and comprehensive understanding of Quality Systems and GMP and good knowledge and reputation in the QA arena and specifically in GMP matters • A comprehensive understanding of the pharmaceutical/drug development process is essential. A detailed scientific understanding of the Product types being supported is desirable • Experienced in leading projects, making decisions, acting courageously and communicating with conviction and inspiration and in building excellent relationships both internally and with external suppliers or service providers • Understanding of Supply Chain processes is desirable Soft skills: •You thrive when you work independently, when leading projects and take pride in structuring your day, knowing that the diverse workload can change the schedule with little notice. • You are a problem solver who can look at solutions in a pragmatic way – coming up with creative solutions whilst still following our strict regulations. • Excellent team working and networking skills • Demonstrates independent judgement and uses risk management in complex situations • Capable of making decisions, acting courageously and communicating with conviction and inspiration • Demands excellence (sets high bar) and delivers • A good communicator with experience of interacting effectively across interfaces Why AstraZeneca At AstraZeneca, we take Quality seriously. Our work is important, valued, and at the forefront of discovery, development, and commercialization. We are always innovating, trialing the latest models and technologies to improve reliability and excellence in our processes. We are proactive, science-based, and driven by our ambition to go far. We are a team of ambitious people who want to achieve. We work together as a team, get our pipeline out to patients sustainably, reliably, and safely. We follow evidence to reach outcomes that benefit patients and AstraZeneca. Make a difference! Apply now and join us in our journey to push the boundaries of science and make a real-life difference to patients. About AstraZeneca Gothenburg Hub Our stunning campus in Gothenburg is one of AstraZeneca’s three strategic science centers. The site is home to over 2,500 employees, from 50 different nationalities. Gothenburg includes the complete range of functions, and as such offers plenty of development opportunities for a wide range of professionals. Our science teams in Gothenburg collaborate with academic and industry partners in Sweden and globally. And the site itself has been designed with collaboration in mind. From the Coffee Lab to exercise areas, we’ve built a series of environments where innovation can happen. This is a consultancy assignment, and during the assignment, you will be employed by Logent. Visa mindre

På Knightec förstår vi att förbättrad livskvalitet för patienter genom att säkra medicintekniska produkter är av yttersta vikt. Genom att balansera kvalitet och regulatorisk efterlevnad under produktutvecklingsprocessen, spelar du en avgörande roll i att introducera ny teknik och effektivare medicinteknisk utrustning till marknaden.
Varför detta jobbet är för dig:
Du vill förbättra livskvaliteten för patienter genom säkra medicintekniska produkter
Du strävar efter att hitta rätt balans mellan kvalitet och regulatorisk efterlevnad under produktutvecklingsprocessen
Du vill vara en viktig del av att introducera ny teknik och mer effektiv medicinteknisk utrustning till marknaden
Du vill använda hela din kompetens i varierande projekt, från start-ups till väletablerade internationella företag
Du har erfarenhet inom Design Control, teknisk dokumentation, Quality Assurance eller regulatoriska krav och vill ta stort ansvar i dina uppdrag
Du värdesätter att arbeta i en miljö präglad av tillit, transparens och samarbete



Dina erfarenheter:
Dina viktigaste egenskaper är din vilja att lära och dela din kunskap med andra. Då vår ambition är att hjälpa våra kunder ta nästa steg in i framtiden genom digitala verktyg, ser vi att du har intresse för ny teknik och digitalisering. Extra intressant är det om du har erfarenhet eller intresse för att arbeta med kvalitetssäkring av mjukvara eller uppkopplad utrustning.
Du har även:
Ingenjörsexamen i bioteknik, medicinteknik, kemiteknik eller liknande
Minst 3 års erfarenhet av att ha arbetat med produktutvecklingskvalitet inom den medicintekniska industrin, exempelvis Design Control, CE-märkning, Quality Assurance, Regulatory Affairs eller kvalitetsledningssystem
God kunskap om relevanta regulatoriska krav och standarder som MDD/MDR, ISO 13485, ISO 14971, IEC 62304 och GMP
Utmärkta kommunikationsförmågor på svenska och engelska



Skapa en karriär att vara stolt över:
Som senior konsult hos oss är du inte bara en del av teamet – du är en nyckelspelare i vår nationella satsning på Medtech Compliance. Genom att driva utbildningar, workshops och strategiska initiativ formar du vår riktning och påverkar både kunder och kollegor på djupet.
Vi erbjuder dig en unik möjlighet att växa professionellt i en organisation där din erfarenhet och dina idéer värdesätts. Genom mentorskap och samarbete med branschens bästa får du chansen att ytterligare fördjupa din kompetens och ta din karriär till nästa nivå.

En spännande resa med Knightec Group
Vi på Knightec går nu samman med vårt systerbolag Semcon och bildar Knightec Group. Tillsammans blir vi den ledande aktören i norra Europa inom produkt- och digital tjänsteutveckling – hur häftigt är inte det? Vårt gemensamma erbjudande blir både bredare och djupare, vilket gör att vi kan ta oss an stora, strategiska kundprojekt på högsta nivå av innovation och komplexitet. För våra medarbetare innebär detta fantastiska möjligheter till kompetensutveckling och karriärvägar. Låter detta som platsen för dig? Häng med oss på denna spännande resa!

Ansökningsprocessen: Skicka gärna in din ansökan med CV och personligt brev. Ansökningsperioden är öppen tills vidare. Visa mindre

Are you a strategically skilled Project Manager with a global approach? Are you ready to lead and innovate in the world of business planning and operations? If you can envision applying your expertise in a truly meaningful setting, then this may be the role for you!



We have an opening for a Director, Business Planning and Operations (BPO) in the Discovery Sciences organization. The position is placed at our vibrant R&D site in Gothenburg, Sweden. You will report into the Head of Business Planning and Operations, Discovery Sciences and be part of the Discovery Sciences (DS) organization, a function that applies deep scientific and technical expertise to support the delivery of targets and molecules to the early AstraZeneca pipeline.



What you'll do?
As a Director of Business Planning and Operations, you will be at the forefront of workflow optimization and portfolio management. You will implement innovative processes to visualize, monitor, report, and forecast, drive improvement initiatives and lead change programs. In partnership with the Head of BPO and Discovery Sciences' Leadership Team, you will play a pivotal role in the business reporting cycle, including long-term planning (LTP) and mid-term planning (MTP). Your expertise will increase transparency for key stakeholders and advance analytically tracking activities.



Collaboration is key, and you will partner with colleagues to ensure the transparent preparation, tracking, and reporting of strategic investment cases. Working closely with Discovery Sciences Therapeutic Area Project Representatives and Project Leads, you will enhance operational excellence by refining our ways of working and scientific workflows. As a proactive leader, you will independently lead projects, driving and championing new strategies and processes to advance operational activities within the function.



Typical accountabilities may also include:

* Providing operational support to Head of BPO, including data preparation and reporting and overseeing complex activities and events
* Supporting the business cycle including budget, reporting, and risk; business strategy and scorecard tracking and reporting
* Providing direction, guidance, and development coaching to junior members of the BPO team
* Deploying excellent analytical skills in complex strategic issues/proposed projects, quantifying impact on business, and providing recommendations towards innovative solutions
* Ensure efficient and effective management of project information, quality of data, and integrity of information supplied
* Effectively communicate key findings to a range of stakeholders both within and beyond Discovery Sciences



You will also actively network with colleagues within Discovery Sciences, Senior Management within Discovery Sciences and peers in the AstraZeneca BPO community network.



Essential requirements
* Bachelors of Science in a scientific or analytical field
* Considerable experience (5+ years) in business strategy, process optimization and/or portfolio management roles within a pharmaceutical or clinical organisation
* Demonstratable evidence of process improvement and change management experience resulting in positive change
* Excellent communicator across all levels of the business
* Pragmatic, operationally focused and keen to assist others in finding practical solutions
* Confident user of relevant IT systems and software to access, analyse and present data/information in the most effective ways
* Solid analytical skills with the ability to manipulate complex data
* Strong networking skills and an ability to achieve through engaging the cooperation of others



Desirable requirements
* Advanced degree in a scientific or analytical field
* Consultancy experience and/or qualification in process improvement, project management and/or change management
* Experience in delivering large, engaging events
* Expert reputation within the business and/or industry
* Familiarity with AZ systems and processes



Why AstraZeneca?
Our Gothenburg site is one of AstraZeneca's strategic science centers. We thrive in a multinational environment working cross-functionally across the globe with AstraZeneca colleagues as well as academic and industry partners. Our way of life is to develop a working environment that furthers collaboration, openness, and innovation. Therefore, we have built space for meetings, and socializing, where spontaneous meetings can give birth to new innovations.



Work policy
When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace, and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.



What's next?
If you are ready to make a difference - apply today, and we'll make it happen together! We welcome your application until 10th March 2025. Visa mindre

Do you have a passion for Procurement? Would you like to join an award-winning procurement team supporting R&D in one of the world’s leading pharmaceutical companies? If you thrive in an environment of innovation and change in a fast growing organisation, then this could be the role for you.
KellyOCG, a global talent solutions provider, is seeking an Associate Director R&D Procurement, on behalf of our partner, AstraZeneca. This is a 9-month contract role based onsite in Gothenburg, Sweden, where you will be fully integrated in the world of AstraZeneca.
Introduction to role:
Join us at AstraZeneca, a place that champions knowledge-sharing, ambitious thinking, and innovation. We are looking for an integral member to join our Research & Development (R&D) Procurement team. This role has a global remit and you will have accountability for a category in the R&D space.
The role focuses on the development and deployment of global category strategies and initiatives, leading our major supplier relationships, developing deeper relationships with the various stakeholder groups through effective business partnering, and ensuring that the underpinning process improvement and procurement activities deliver the expected business value.
Accountabilities:
In this role, you will be responsible for developing long-term strategic plans for an entire spend category within AstraZeneca. You will manage stakeholder and supplier relationships to ensure that category strategies are highly aligned to current and future business needs and that the supply base is capable of supporting these strategies.
You will lead project initiatives tied to the category strategies to deliver value to the business, lead the implementation of sustainability initiatives with vendors, and lead complex contractual and commercial negotiations.
You will work alongside key stakeholders and align with GPS (Global Procurement Services). You will ensure a data-driven approach to category management and high-quality analytics to deliver insights, capabilities, and results.
Typical Responsibilities:
Lead implementation of category plans to ensure that the underpinning process improvement and procurement activities deliver business value in accordance with the strategic plan and help towards our Sustainability targets.
Develop long term strategic plans for agreed scope of spend area, with a focus on delivering broader value, innovation, and savings.
Support the team in strategic relationship management (customer and supplier) - ensuring Category Strategies are fully aligned to current and future Business need, and we maintain a supply base capable of supporting these strategies.
Work alongside Global Procurement Services (GPS) advising on and driving procurement strategies to make decisions necessary to make purchases in congruence with organizational objectives.
Advise on contracts and agreements for the supply of sophisticated products and services with new and existing suppliers
Cross functionally support Global procurement colleagues and collaborate on setting and completing the strategy.



Application Deadline: February 27. Early applications are encouraged as interviews will be conducted on a rolling basis.
What’s next?
Are you already imagining yourself joining our team? Good, because we can’t wait to hear from you. Visa mindre

Associate Director R&D Procurement - AstraZeneca - Gothenburg - 9-month consultancy assignment

Do you have a passion for Procurement? Would you like to join an award-winning procurement team supporting R&D in one of the world's leading pharmaceutical companies? If you thrive in an environment of innovation and change in a fast-growing organisation, then this could be the role for you.

AstraZeneca is a global, science-led, patient-focused biopharmaceutical company that focusses on the discovery, development and commercialisation of prescription medicines for some of the world's most serious diseases.

Introduction to role:
Join us at AstraZeneca, a place that champions knowledge-sharing, ambitious thinking, and innovation. We are looking for an integral member to join our Research & Development (R&D) Procurement team. This role has a global remit, and you will have accountability for a category in the R&D space.

The role focusses on the development and deployment of global category strategies and initiatives, leading our major supplier relationships, developing deeper relationships with the various stakeholder groups through effective business partnering, and ensuring that the underpinning process improvement and procurement activities deliver the expected business value.

Accountabilities:
In this role, you will be responsible for developing long-term strategic plans for an entire spending category within AstraZeneca. You will manage stakeholder and supplier relationships to ensure that category strategies are highly aligned to current and future business needs and that the supply base is capable of supporting these strategies.

You will lead project initiatives tied to the category strategies to deliver value to the business, lead the implementation of sustainability initiatives with vendors, and lead complex contractual and commercial negotiations.

You will work alongside key stakeholders and align with GPS (Global Procurement Services). You will ensure a data-driven approach to category management and high-quality analytics to deliver insights, capabilities, and results.

Typical Responsibilities:
* Lead implementation of category plans to ensure that the underpinning process improvement and procurement activities deliver business value in accordance with the strategic plan and help towards our Sustainability targets.
* Develop long term strategic plans for an agreed scope of spend area, with a focus on delivering broader value, innovation, and savings.
* Support the team in strategic relationship management (customer and supplier) - ensuring Category Strategies are fully aligned to current and future Business needs, and we maintain a supply base capable of supporting these strategies.
* Work alongside Global Procurement Services (GPS) advising on and driving procurement strategies to make decisions necessary to make purchases in congruence with organisational objectives.
* Advise on contracts and agreements for the supply of sophisticated products and services with new and existing suppliers
* Cross functionally supports Global procurement colleagues and collaborates on setting up and completing the strategy.

Essential Requirements:
* Bachelor's degree or equivalent
* Significant experience in a procurement environment
* Significant experience in Category Management (preferably in R&D/Pharma)
* Project management and change management
* Good solid understanding of the research environment
* Strong communication skills and ability to influence others
* Comfort with risk and ambiguous situations

Desirable:
* People leadership skills

What's next?
Are you already imagining yourself joining our team? Good, because we can't wait to hear from you. Click 'apply now' to forward an up-to-date copy of your CV, or call us now. If this job isn't quite right for you, but you are looking for a new position, please contact us for a confidential discussion on your career.

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements. Visa mindre

Are you an experienced drug discovery scientist with expertise in pharmacokinetics, pharmacology and drug metabolism (DMPK)? Would you like to apply your expertise in a global company that follows the science and turn ideas into life changing medicines? Then you could be the new colleague we are looking for!



We are now looking for an experienced and motivated individual to join the team as a DMPK Project Leader. The position is placed at AstraZeneca's dynamic R&D site in Gothenburg, Sweden. Working at AstraZeneca means being entrepreneurial, following the science, scrutinizing data and details simultaneously with holistic thinking and through teamwork make progress. Your level of professional experience will be relevant for your initial career level (Associate Principal Scientist or Principal Scientist).



Respiratory & Immunology (R&I) is one of the three main therapeutic research areas within AstraZeneca. Early R&I is a global function, with research units in Gaithersburg (US), Cambridge (UK) and Gothenburg (Sweden), and delivers candidate drugs into late-stage clinical development. DMPK interacts with other functions in supporting Early R&I projects all along the value chain, from target selection all the way to market launch and Life cycle management.



What you'll do:
With a true passion for drug discovery you will support our portfolio within the R&I therapeutic area. In the DMPK project lead role you will work collaboratively with project representatives from other disciplines. These may include biology, antibody Discovery/Protein Engineering, medicinal chemistry, safety, clinical pharmacology, and pharmaceutical sciences, where your task is to influence candidate profiling by providing the necessary DMPK support for clinical investigations.



It is your responsibility to ensure delivery of all DMPK related activities. These include preclinical PK experiments, in vitro ADME and biotransformation to yield pharmacokinetic understanding. Furthermore, assisting design of pharmacodynamic studies that ultimately delivers a pharmacological assessment underpinning human dose prediction.



You will work on projects from candidate selection to Phase 2a. We believe that you have a solid understanding of DMPK, a working knowledge of pharmacology, and that you will be able to provide expert advice and interpretation of complex drug discovery data.



Main Duties and Responsibilities
* Communicate scientific progresses both externally and internally
* Deliver DMPK input and data to projects within agreed timelines and to the right quality
* Apply an understanding of DMPK to support/influence compound profiling, project progression and project strategy
* Define and deliver a translational quantitative PKPD strategy in projects, so that effective conclusions can be made
* Contribute to estimation of safety margins and report results and interpretations to project teams and internal governance bodies
* Responsible for leading, coordinating and engaging with R&I DMPK colleagues in project related activities
* Prepare clear presentations related to the above for internal governance bodies

Essential requirements:
* PhD or equivalent experience in a relevant field
* Expert in DMPK sciences with profound knowledge of drug discovery and development processes
* Broad experience across different modalities (small molecules & biologics) drug development (PK & Bioanalysis)
* Experience with regulatory submissions for biologics and small molecules
* Good knowledge of all DMPK assays including the use of in silico tools for PK prediction
* Experience in project leadership
* Collaborative mindset
* Team player
* Proactive and good communication skills

Why AstraZeneca?
At AstraZeneca we're dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There's no better place to make a difference to medicine, patients and society. An inclusive culture that champions diversity and collaboration. Always committed to lifelong learning, growth and development.

Work policy:
When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working give us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

What's next!
If you are ready to make a difference - apply today, and we'll make it happen together! We welcome your application until March 14, 2025.

Where can I find out more?

Life at AstraZeneca

This is what we're made of

Relocate to Gothenburg Visa mindre

Do you have expertise within in vitro cardiovascular biology and enjoy working in the lab? Would you like to apply your expertise in a global company that is accelerating innovative science and turn ideas into life changing medicines? Join us to discover future treatment of Cardiovascular, Renal and Metabolic diseases!

At AstraZeneca, we work at the cutting edge of science to develop the ground-breaking medicines of the future – here we do things that have never been done before. We put patients first and strive to meet their unmet needs worldwide.

About the position
CVRM is one of three main therapeutic research areas within AstraZeneca. Early CVRM has a patient-centric approach for discovering novel treatments for patients with cardiovascular-, chronic kidney- and metabolic disease and delivers candidate drugs into late-stage clinical development. In the Bioscience Cardiovascular department, we focus on identifying and validating new drug targets for treatment of patients with cardiovascular disease and heart failure, as well as evaluating pharmacological aspects, e.g. efficacy and mechanism of action, of potential new drug candidates. The in vitro team delivers key data to projects across all phases of the drug discovery and development process, and we work with different modalities such as small molecules, modified mRNA, antibodies, cell therapy, antisense oligonucleotides and peptides.

We are now recruiting a Senior Scientist with expertise in cardiovascular biology to join the Bioscience Cardiovascular in vitro team within the Cardiovascular, Renal and Metabolism (CVRM) therapeutic area at AstraZeneca in Gothenburg, Sweden.

Responsibilities
As a Senior Scientist you will play a key role in driving science and projects within the cardiovascular area forward. This is a lab-based role where you will explore novel drug targets with key in vitro data. Collaboration is critical for successful delivery of drug projects, and you will work closely with scientists/teams from a wide range of different functions within AstraZeneca as well as with external partners and collaborators. You will work with in vitro biology using cell lines, pluripotent stem cells (PSC) and primary cardiovascular cells along with molecular and functional biology techniques. You will have the opportunity to try novel techniques and ideas required for progressing existing portfolio and novel science. Responsibilities include:

- Independently design, develop and run in vitro studies and assays for target identification and validation
- Work with molecular biology methods, imaging and assays for functional readouts such as contractility and cardiac metabolism
- Contribute to communications of scientific findings through publications in scientific journals and at meetings
- Proactively contribute to a vibrant and innovative working environment where improvements and new ideas are adopted and freely shared

Your profile
Essential for the role:

• PhD or master’s degree in biology, pharmacology, cardiovascular disease or similar
• Strong experience in cell and molecular biology, biochemistry and relevant in vitro/ex vivo assays within the cardiovascular area
• Experience in handling and manipulating relevant PSC cells and primary human and animal cardiac cell types, including cardiomyocytes
• Excellent English communication skills, both spoken and in writing

Desirable for the role:

• Experience with cardiomyocyte biology and function in healthy and diseased systems
• Background in drug discovery and development in the pharmaceutical industry
• Background in Vivo and in Vitro

About the organisation
This is a consultant assignement at AstraZeneca Göteborg for 1 year starting in April 2025. During this time you will be hired by QRIOS.

About Astra Zeneca:
AstraZeneca is a major international healthcare company engaged in the research, development, manufacture and marketing of prescription pharmaceuticals and the supply of healthcare services. But we are more than one of the world’s leading pharmaceutical companies - at AstraZeneca, we are proud to have a unique culture that inspires innovation and collaboration. Here, employees are empowered to express diverse perspectives - and are made to feel valued, energized and rewarded for their ideas and creativity. Visa mindre