Lediga jobb som Biokemist i Göteborg

The University of Gothenburg tackles society’s challenges with diverse knowledge. 58 000 students and 6800 employees make the university a large and inspiring place to work and study. Strong research and attractive study programmes attract researchers and students from around the world. With new knowledge and new perspectives, the University contributes to a better future. 

Subject area 
Structure and function of membrane proteins in native systems.

Subject area description 
Membrane proteins such as transporters and G-protein-coupled receptors (GPCRs) are central to cellular signaling and represent some of the most important targets in modern drug discovery. Yet, resolving their structures in physiologically relevant states remains a key frontier in structural biology.

Duties 
Please see the full ad here.

The research will focus on the development of new methods for structure determination in native systems, such as neuronal vesicles. Duties include protein design and modeling, cloning, expression in insect and mammalian cells, and purification followed by structure determination with cryo-EM and subsequent data analysis. The candidate will also apply biochemical analysis methods (for example, APEX and proteomics). The candidate is expected to work independently and contribute to project planning. The candidate is also expected, in collaboration with other group members, to produce scientific publications, analyze data and present these results at scientific conferences.

Eligibility 
The eligibility criteria for employing teaching staff are set out in Chapter 4 of the Higher Education Ordinance and in the Appointment Procedure for Teaching Posts at the University of Gothenburg. 

To be eligible for appointment as a postdoc, the applicant is required to have a doctoral degree, a doctoral degree in art or a foreign degree that is deemed to be equivalent to a doctoral degree. This eligibility requirement must be met before the employment decision is made. 

In the first instance, those who have completed their degree no more than three years prior to the end of the application period shall be considered. Those who have completed their degree more than three years prior to the end of the application period may also be considered in the first instance if special grounds exist. Special grounds relate to leave of absence due to illness, parental leave, commissions of trust within union organisations, service within the defence services or other similar circumstances, as well as clinical service or service/assignment relevant to the subject area.  

Assessment criteria 
This postdoctoral position is designed for an independent and highly motivated scientist who is eager to drive method development while applying it to biologically and medically relevant systems. The successful candidate will play a central role in shaping the project, contributing intellectually to experimental design, and advancing cutting-edge structural biology research with clear relevance to neuroscience and drug discovery.

We are looking for a candidate with an interest in protein design and structural biology. The applicant must have a PhD in a relevant area of research such as medicine/biology/chemistry/pharmacology or related fields (for example structural biology, biochemistry or biophysics). The successful candidate should have extensive experience in structural biology (preferably cryo-EM), along with experience in cell cultivation (preferably eukaryotic cells), as well as in protein purification. The applicant is expected to have published several articles in well-established, reputable scientific journals. Great emphasis will be placed on the candidate’s personal suitability for the position and interest in the subject area as well as their long-term research goals. The work involves close collaborations with other researchers and thus demands flexibility and a willingness to travel for data collection purposes. Excellent communication skills (spoken and written) in English are a prerequisite for the position.

Regulations for the evaluation of qualifications for academic positions are given in Chapter 4, Section 3 - 4 of the Higher Education Ordinance.

Employment 
The employment is full time and temporary, two years with the possibility of one year's extension, with placement at the Institute of Biomedicine. First day of employment as agreed.

Selection process 
Help for applicants.

Contact information 
If you have any questions about the position, please contact Linda Johansson; email: [email protected]; telephone: +46(0)766183244.

Unions 
Union representatives at the University of Gothenburg can be found here:?https://www.gu.se/om-universitetet/jobba-hos-oss/hjalp-for-sokande 

Application 
Submit your application via the University of Gothenburg’s recruitment portal by clicking the “Apply” button. It is your responsibility to ensure that the application is complete as per the vacancy notice, and that the University receives it by the final application deadline.  

The application should contain:

- A cover letter giving a brief description of previous research experience, and a motivation to why you are applying

- A CV including a list of publications

- Proof of completed PhD

- Contact details of two references

Applications must be received by: 2026-04-04

 

? 

Information for International Applicants 

Choosing a career in a foreign country is a big step. Thus, to give you a general idea of what we and Gothenburg have to offer in terms of benefits and life in general for you and your family/spouse/partner please visit: 

https://www.gu.se/en/about-the-university/welcome-services 
https://www.movetogothenburg.com/ 

The University works actively to achieve a working environment with equal conditions, and values the qualities that diversity brings to its operations.

Salaries are set individually at the University.

In accordance with the National Archives of Sweden’s regulations, the University must archive application documents for two years after the appointment is filled. If you request that your documents are returned, they will be returned to you once the two years have passed. Otherwise, they will be destroyed.

In connection to this recruitment, we have already decided which recruitment channels we should use. We therefore decline further contact with vendors, recruitment and staffing companies. Visa mindre

Göteborgs universitet möter samhällets utmaningar med mångsidig kunskap. 58 000 studenter och 6800 medarbetare gör universitetet till en stor och inspirerande arbetsplats. Stark forskning och attraktiva utbildningar lockar forskare och studenter från hela världen. Med ny kunskap och nya perspektiv bidrar Göteborgs universitet till en bättre framtid.Institutionen för kemi och molekylärbiologi bedriver högkvalitativ forskning och utbildning inom kemiska vetenskaper och molekylära livsvetenskaper. Vår forskning och utbildning fokuserar på en djup förståelse av kemiska och biologiska processer i celler och i miljön. Vi ansvarar för forskarutbildning inom ämnesområdet Naturvetenskap med inriktning mot kemi, biofysik, biologi och utbildningsvetenskap. Därtill är institutionen värd för utbildningsprogram i molekylärbiologi, bioinformatik, kemi, organisk kemi och läkemedelskemi samt receptarieutbildningen. Institutionen är en internationell miljö med tvärvetenskapliga samarbeten inom både forskning och utbildning, och bidrar starkt till Göteborgs universitets topprankning inom life science. Institutionens verksamhet bedrivs i Natrium, Medicinareberget i Göteborg.

Tietze-labbet är en del av Wallenbergcentrum för molekylär och translationell medicin (https://www.gu.se/en/molecular-translational-medicine), vilket bedriver translationell forskning inom områdena metabolism, neurovetenskap, cancer, inflammation, degenerativa sjukdomar, genomik och livsvetenskaplig kemi. Tietze-labbet (www.tietze-lab.com) är inriktat på att driva utvecklingen inom bioinspirerad kemiteknik för framställning av peptidbaserade molekyler och material. Vårt team arbetar med att skapa innovativa lösningar för diagnostik och målsökande läkemedelsleverans. 

Vi söker en forskningsassistent som kan hjälpa till med analyser och genomförande av tester relaterade till vår biosensor.

Arbetsuppgifter 

• Förberedelse av prover för testning
• Analyser av prover via biosensor
• Analyser av prover via HPLC & LC-MS
• Installation av hårdvara och drivru
• Arbete med öppen hårdvaruplattform
• Labbarbete
• Automation av flödesschema
• Elektronikarbete
• Tolkning av analysvärden och hur de relaterar till demenssjukdomar när det kommer till neurotoxikologi
• Användning av matlab och eventuellt andra högnivåspråk

Kvalifikationer 
Krav för anställningen:


• Kandidatexamen i farmaci, kemi eller biologi
• God kunskap om analysmetoder som HPLC och LC-MS
• Erfarenhet av arbete i forskningslaboratorium inom organisk kemi
• Erfarenhet av öppna hårdvaruplattformar, e.g. MATLAB
• Kunskap inom elektronik, arbete med microfluidics och elektroder och förstå elektroniken bakom
• Mycket god laboratorievana
• Mycket goda kunskaper i engelska, både i tal och skrift.

Meriterande för anställningen:


• Ha erfarenhet iinom electroteknik
• Erfarenhet av IT-teknik, har byggt datorer eller databaser
• Kunskap av programmeringsspråk

Anställning 
Anställningen är en tidsbegränsad anställning på 50% under 6 månader med placering vid institutionen för kemi och molekylärbiologi.

Kontaktuppgifter för anställningen 
Har du frågor om anställningen är du välkommen att kontakta professor Alesia Tietze,e-post: [email protected]

Fackliga?organisationer 
Fackliga företrädare vid Göteborgs universitet hittar du här:?https://www.gu.se/om-universitetet/jobba-hos-oss/hjalp-for-sokande 

Ansökan 
Du söker anställningen genom att registrera via Göteborgs universitets rekryteringsportal ReachMee genom att klicka på knappen "Ansök". Du som sökande ansvarar för att ansökan är komplett i enlighet med annonsen och att den är universitetet tillhanda senast sista ansökningsdag. Din ansökan skall innehålla:


• Meritförteckning/CV
• Personligt brev
• Kontaktuppgifter till minst två referenser.
• Kopia av examensbevis samt ev. andra intyg/betyg som du önskar åberopa. De åberopade meriterna ska vara dokumenterade, bestyrkta och översatta till engelska.

Samtliga bilagor ska vara namngivna på ett sätt som tydligt visar dess innehåll.

Ansökan ska vara inkommen senast: 2026-01-07

 

Universitetet arbetar aktivt för en arbetsmiljö med jämställda förhållanden och sätter värde på de kvalitéer mångfald tillför verksamheten.

Universitetet tillämpar individuell lönesättning.

Enligt Riksarkivets föreskrifter är universitetet skyldigt att förvara ansökningshandlingar i två år efter tillsättningsbeslutet. Om du som sökande till en anställning särskilt begär tillbaka dina handlingar återsänds de när de två åren har förflutit, i annat fall kommer de att gallras ut.

Till bemannings- och rekryteringsföretag och till dig som är försäljare: Göteborgs universitet anlitar upphandlad annonsbyrå i samband med rekrytering av personal. Vi undanber oss vänligen men bestämt direktkontakt med bemannings- och rekryteringsföretag samt försäljare av jobbannonser. Visa mindre

Do you have strong ambition to shape the future of the food industry? Are you well-versed in microbiology and food safety? Do you want to be part of developing the safe and sustainable foods of tomorrow? Then you might be the person we’re looking for!
The Microbiology and Hygiene unit is now looking for an independent and proactive researcher to lead and develop our research and collaborations within food microbiology.
About Us The Microbiology and Hygiene unit is part of the Food Research and Innovation department at RISE. We work with research and innovation in microbiology, process hygiene, and biotechnology, with a primary focus on food and the food industry. Our work is mainly applied research, development, and problem-solving in assignments aimed at supporting companies and partners. We take an interdisciplinary approach to create holistic solutions, and we benefit from a wide range of competencies within RISE that strengthen our offering — including product design, process technology, aroma, texture, sensory analysis, nutrition, and sustainability assessments.
About the Role As a researcher, you will initiate, develop, and lead your own projects in applied research, in close collaboration with colleagues and external partners. You will take on a project management role that includes budgeting and administration, as well as planning and leading the practical project work. You will also contribute your expertise and experience to other projects, and to some extent lead commercial assignments for clients.
A key part of the role is to contribute to the growth of our research activities by actively applying for funding to secure project financing. You are expected to build a project portfolio within your area of expertise, with the opportunity to shape project development in a direction that aligns with your skills and interests — within the strategic framework of the organization and with a focus on meeting societal and market needs.
The role also includes responsibility for delivering scientific and technical results in accordance with budget and timeline. You will establish and maintain networks within the food industry, academia, and public funding bodies, and help increase visibility of our work through publications and participation in relevant activities.
The position is based in Gothenburg, with some flexibility for hybrid work.
Who are you To succeed in this role, you have a genuine interest in applied research and food. You are driven by challenges and solutions and understand what creates value for customers and partners. You are proactive and willing to take the lead in driving your research area forward — even when it means stepping into unfamiliar territory. You are skilled at building relationships and have the ability to identify needs, package offerings, and create meaningful collaborations.
The work requires independence, but it is equally important that you have an interdisciplinary mindset and enjoy working together with colleagues and external partners from both academia and industry.
Requirements for the Role:
· PhD in a relevant field, with expertise in microbiology focused on food safety or process hygiene
· Several years of professional experience in the food industry, public authority, or equivalent after completing your PhD
· Documented experience in securing project funding through applications and grants from public financiers
· Experience in project management within research, development, or innovation projects involving multiple stakeholders from industry and academia
· Excellent command of English, both spoken and written
A well-established network within the Swedish food industry is highly meritorious, as is knowledge of industrial processes and risk analysis, as well as molecular methods for detection and quantification. Our corporate language is Swedish, and we offer training if needed.
Are we right for each other? RISE offers an inclusive workplace with a dynamic environment that gives you opportunities for development both professionally and personally. You will work in a team of committed colleagues to tackle exciting societal challenges.
Welcome with you application! If you are interested and want to know more you are welcome to contact unit manager Jenny Veide Vilg, [email protected]. Sista ansökningsdag är den  2025. Urval och intervjuer. The application deadline is September 28th. Please note that selection and interviews may take place continuously during and after the application period.
Please attach or link to your list of publications in your application. Our union representatives are Ingemar Petermann, SACO, +46 10 228 41 22 and Linda Ikatti, Unionen, +46 10 516 51 61 Visa mindre

Göteborgs universitet möter samhällets utmaningar med mångsidig kunskap. 56 000 studenter och 6 600 medarbetare gör universitetet till en stor och inspirerande arbetsplats. Stark forskning och attraktiva utbildningar lockar forskare och studenter från hela världen. Med ny kunskap och nya perspektiv bidrar Göteborgs universitet till en bättre framtid.Neurokemis laboratorium inom Sektionen för psykiatri och neurokemi, vid Institutionen för neurovetenskap och fysiologi, Sahlgrenska akademin, utlyser nu en tillsvidareanställning som forskningssamordnare. Vår forskning fokuserar på att utveckla och förbättra diagnostiska verktyg för neurodegenerativa sjukdomar. Vi har lång erfarenhet av tekniker för både produktion av monoklonala antikroppar och rekombinanta proteiner för utveckling av högkänsliga mätmetoder. Vi har stor kunskap om att validera (både analytiskt och kliniskt) nya metoder för att implementera dem i klinisk laboratoriepraxis och vi driver aktivt projekt med internationella samarbeten. På senare tid har vi utvecklat metoder för kvantifiering av Alzheimer-relaterade proteiner i blod (t.ex. metoder för fosforylerat tau), som vi nu mäter rutinmässigt i akademiska och kliniska studier.

Gruppen är mycket aktiv både nationellt och internationellt, med samarbeten som spänner över ledande forskningscentra, kliniska institutioner och läkemedelsföretag. Vårt team består av studenter, forskare och personal från olika kulturella och professionella bakgrunder, vilket skapar en stimulerande och inkluderande arbetsmiljö. Vi värdesätter samarbete, kunskapsdelning och professionell utveckling stort och erbjuder en atmosfär som är både vetenskapligt ambitiös och stödjande för individuell utveckling.

Arbetsuppgifter
Forskningssamordnaren kommer att vara ansvarig för samordning och administration av forsknings- och kliniska läkemedelsstudier inom forskargruppen för neurokemi. Rollen innebär nära samarbete med akademiska, kliniska och industriella partners, inklusive läkemedelsföretag, Sahlgrenska Universitetssjukhuset och Göteborgs universitet (GU).

Huvudsakliga arbetsuppgifter:


• Koordinera och driva forsknings- och kliniska läkemedelsstudier från start till avslut.
• Bistå i planering av studier och upprättande av tidplaner.
• Hantera avtal och kontrakt i samarbete med GU:s jurister och externa partners.
• Vara kontaktperson gentemot läkemedelsföretag i multicenterstudier och industrisponsrade studier.
• Ansvara för regulatoriska och etiska ansökningar, inklusive till Etikprövningsmyndigheten vid behov.
• Stödja framtagning av ansökningar om forskningsmedel och projektbidrag.
• Bistå med projektbudgetering, ekonomisk uppföljning och resursfördelning.
• Säkerställa att studierna uppfyller krav enligt Good Clinical Practice (GCP), GDPR och interna riktlinjer.
• Upprätthålla studiedokumentation, databaser och register enligt kvalitetskrav.
• Koordinera kommunikationen mellan forskare, kliniker och samarbetspartners.
• Bidra till framtagning av lägesrapporter vid behov.
• Organisera forskningsmöten och andra relaterade administrativa uppgifter.

Kvalifikationer
Anställningen kräver en kandidatexamen inom bioteknik, biokemi, molekylärbiologi, farmakologi, neurovetenskap eller ett närliggande område. En masterexamen eller doktorsexamen är meriterande. Den sökande bör ha grundläggande förståelse för regulatoriska, etiska och kvalitetsmässiga krav inom kliniska och forskningsstudier, inklusive Good Clinical Practice (GCP), GMP/GLP-standarder, dataskydd och GDPR, samt erfarenhet av monitorering av kliniska prövningsplatser och dokumentation av studier.

Vi söker dig med starka färdigheter inom projektledning, med dokumenterad förmåga att hantera flera studier eller projekt parallellt. Detta inkluderar ansvar för budgetering, tidsplanering, resursplanering, hantering av leverantörer och avtal, samt riskbedömning. Du bör även ha utmärkta administrativa och organisatoriska färdigheter, såsom:


• Noggrann dokumentation och arkivering
• Koordinering av provlogistik och kommunikation med studieplatser
• Avtalshantering
• Uppföljning av ekonomi

Erfarenhet av att skriva ansökningar om forskningsmedel eller bidrag, särskilt med fokus på budgetarbete, samordning mellan flera intressenter och uppfyllande av rapporteringskrav, är mycket meriterande. Kandidaten ska ha mycket goda samarbets- och kommunikationsförmågor, med förmåga att samarbeta effektivt med interna forskargrupper, kliniska samarbetspartners på sjukhuset, externa aktörer inklusive läkemedelsföretag och juridiska representanter samt tillsynsmyndigheter. Anställningen kräver mycket goda kunskaper i engelska, både i tal och skrift, och är ett krav. Goda kunskaper i svenska är önskvärt. Vi lägger stor vikt vid personlig lämplighet. 

Anställning
Anställningen är en tillsvidareanställning, 100% av heltid, med placering tills vidare vid Institutionen för neurovetenskap och fysiologi. Tillträde: snarast eller enligt överenskommelse. Provanställning kan komma att tillämpas. 

Kontaktuppgifter för anställningen
Har du frågor om anställningen är du välkommen att kontakta forskare Andrea Lessa Benedet, e-post: [email protected]

Ansvarig chef är professor/sektionschef Henrik Zetterberg, tfn: +46 768 672 647, e-post: [email protected]

Fackliga organisationer
Fackliga företrädare vid Göteborgs universitet hittar du här: https://www.gu.se/om-universitetet/jobba-hos-oss/hjalp-for-sokande

Ansökan
Du söker anställningen via Göteborgs universitets rekryteringsportal genom att registrera din ansökan elektroniskt via hemsidan: https://www.gu.se/jobba-hos-oss/lediga-anstallningar

Ansökan ska vara inkommen senast: 2025-10-28

Universitetet arbetar aktivt för en arbetsmiljö med jämställda förhållanden och sätter värde på de kvalitéer mångfald tillför verksamheten.

Universitetet tillämpar individuell lönesättning.

Enligt Riksarkivets föreskrifter är universitetet skyldigt att förvara ansökningshandlingar i två år efter tillsättningsbeslutet. Om du som sökande till en anställning särskilt begär tillbaka dina handlingar återsänds de när de två åren har förflutit, i annat fall kommer de att gallras ut.

Till bemannings- och rekryteringsföretag och till dig som är försäljare: Göteborgs universitet anlitar upphandlad annonsbyrå i samband med rekrytering av personal. Vi undanber oss vänligen men bestämt direktkontakt med bemannings- och rekryteringsföretag samt försäljare av jobbannonser. Visa mindre

The University of Gothenburg tackles society’s challenges with diverse knowledge. 56 000 students and 6 600 employees make the university a large and inspiring place to work and study. Strong research and attractive study programmes attract researchers and students from around the world. With new knowledge and new perspectives, the University contributes to a better future. 

This postdoctoral position is part of a research project funded by a Wallenberg Scholar grant. The postdoc will work with a multidisciplinary team with expertise in molecular biology, biochemistry, and computational analysis to investigate how mitochondrial DNA replication and gene expression are regulated, and how dysregulation of these processes contributes to human disease.

Subject area 
Studies on mitochondrial DNA replication and its regulation

 
Subject area description 
Mitochondrial DNA replication is a crucial process for maintaining mtDNA integrity and stability, which is essential for mitochondrial function and cellular energy production. Disruptions in this process can lead to mtDNA deletions or loss of mtDNA, which in turn is associated with various mitochondrial diseases, neurodegenerative conditions, and aging. We combine in vitro biochemistry and cell biology to study the molecular mechanisms that regulate mtDNA replication. A particular focus is on understanding how disease-associated mutations affect this process and developing new therapies to prevent mtDNA deletions and loss of mtDNA.

 

Duties 
In this project, the candidate will investigate the biochemical and cell biological mechanisms that govern mitochondrial DNA replication. The focus is on understanding how the involved proteins interact and how disease-causing mutations affect replication efficiency and genome stability. The work includes a combination of in vitro biochemical analyses and cell-based methods. More information about the research group and our work can be found at www.falkenberglab.org.

 
Eligibility 
The eligibility criteria for employing teaching staff are set out in Chapter 4 of the Higher Education Ordinance and in the Appointment Procedure for Teaching Posts at the University of Gothenburg. 

To be eligible for appointment as a postdoc, the applicant is required to have a doctoral degree, a doctoral degree in art or a foreign degree that is deemed to be equivalent to a doctoral degree. This eligibility requirement must be met before the employment decision is made. 

In the first instance, those who have completed their degree no more than three years prior to the end of the application period shall be considered. Those who have completed their degree more than three years prior to the end of the application period may also be considered in the first instance if special grounds exist. Special grounds relate to leave of absence due to illness, parental leave, commissions of trust within union organisations, service within the defence services or other similar circumstances, as well as clinical service or service/assignment relevant to the subject area.  

 

Assessment criteria 
We are seeking a highly motivated individual with solid experience in protein biochemistry and cell biology. Knowledge of mitochondrial systems and documented experience in cloning, mutagenesis, gene expression, cell culture, working with radioactively labeled isotopes, as well as in vitro DNA replication and/or transcription, are considered advantageous. The work involves collaboration both within and outside the research group, making strong teamwork and communication skills essential. The candidate is expected to be enthusiastic, capable of planning and conducting research independently, and demonstrate a strong scientific curiosity. Fluency in spoken and written English is required, as we operate in an international environment.

Regulations for the evaluation of qualifications for academic positions are given in Chapter 4, Section 3 - 4 of the Higher Education Ordinance.

 

Employment 
The employment is full time and temporary, two years with the possibility of one year's extension, with placement at the Institute of Biomedicine. First day of employment as agreed.

 

Contact information 
If you have any questions about the position, please contact Maria Falkenberg, Professor, e-mail: [email protected]. 

 

Unions 
Union representatives at the University of Gothenburg can be found here:?https://www.gu.se/om-universitetet/jobba-hos-oss/hjalp-for-sokande 

 

 

Application 

Submit your application via the University of Gothenburg’s recruitment portal by clicking the “Apply” button. It is your responsibility to ensure that the application is complete as per the vacancy notice, and that the University receives it by the final application deadline.  

The application should contain:

- A cover letter giving a brief description of previous research experience, and a motivation to why you are applying

- A CV including a list of publications

- Contact details of two references

- Proof of completed PhD

Applications must be received by: 2025-06-03

  

Information for International Applicants 

Choosing a career in a foreign country is a big step. Thus, to give you a general idea of what we and Gothenburg have to offer in terms of benefits and life in general for you and your family/spouse/partner please visit: 

https://www.gu.se/en/about-the-university/welcome-services 
https://www.movetogothenburg.com/ 

The University works actively to achieve a working environment with equal conditions, and values the qualities that diversity brings to its operations.

Salaries are set individually at the University.

In accordance with the National Archives of Sweden’s regulations, the University must archive application documents for two years after the appointment is filled. If you request that your documents are returned, they will be returned to you once the two years have passed. Otherwise, they will be destroyed.

In connection to this recruitment, we have already decided which recruitment channels we should use. We therefore decline further contact with vendors, recruitment and staffing companies. Visa mindre

Are you a passionate scientist eager to work at the forefront of sample management technologies? Do you want to contribute to life-changing projects and be part of an innovative, collaborative team? If so, we have an exciting opportunity for you!

About the Role

AstraZeneca is seeking a motivated and engaged Research Scientist to join its Compound Management team at the dynamic R&D site in Gothenburg. This role is responsible for the storage and timely supply of compounds to AstraZeneca’s drug discovery projects. Utilizing highly automated liquid handling systems, the Research Scientist will ensure the efficient provision of molecules to AstraZeneca scientists and partner organizations.

As part of the Discovery Sciences organization, this position operates within a first-class scientific environment, supporting drug discovery efforts across AstraZeneca’s Therapeutic Areas. AstraZeneca fosters an innovative and collaborative workplace where scientific excellence drives progress in developing life-changing medicines.

Key responsibilities include:

•
Supporting drug discovery projects by providing compounds in the requested format, such as assay-ready plates, serially diluted mother plates, formulations, and solids.

•
Designing, performing, and interpreting experiments independently to investigate process improvements and evaluate new technologies.

•
Collaborating closely with internal project teams to understand and meet drug discovery needs.

•
Rapidly addressing customer queries regarding Compound Management orders, software, processes, and capabilities.

•
Leading development projects to drive continuous improvement within the local team and global department.

•
Achieving personal scientific visibility through project contributions, internal presentations, and publications.

About You

To thrive in this role, you should be comfortable working in a fast-paced, goal-oriented environment while maintaining a team-focused attitude. You have excellent communication skills, a proactive mindset, and a customer-focused approach. You are passionate about science, technology, and innovation and have a strong understanding of the drug discovery process.

Qualifications:

Essential:

•
BSc or MSc in Chemistry, Biotechnology, or Chemical Engineering.

•
Excellent communication skills and strong work ethics.

•
Strong problem-solving skills and ability to identify and implement process improvements.

•
Proven ability to perform a range of practical and complex laboratory tasks to a high standard.

•
Passion for science, technology, and innovation, with an understanding of the drug discovery process.

Desirable:

•
Previous experience in a compound management role and familiarity with operating integrated automation equipment, such as liquid handlers and scheduling software.

•
Some experience with IT (, Python, or Java coding) is an advantage.

As One of Us

As an employed staffing consultant at Lernia, you will always receive a competitive salary, vacation benefits, pension contributions, insurance coverage, and be part of our collective agreement. We care about your well-being, which is why we offer all our consultants wellness allowances and access to occupational health services. During your employment, you will have a dedicated consultant manager responsible for your assignment, ensuring you thrive at your workplace while supporting and developing you in your professional role.

About Lernia

Lernia is one of Sweden's leading staffing and recruitment companies, with a presence across the country. Through our extensive network, we offer exciting jobs with attractive employers and brands, helping you develop your skills and career, both in the short and long term.

How to Apply

To apply for this position, click on the "Apply" link above and fill out the form. For any questions or inquiries, please contact recruiter Oscar Sahlin at [email protected].

We conduct interviews on an ongoing basis, so please submit your application as soon as possible! Visa mindre

Are you passionate about sustainability and biotech innovation? Join our dynamic team to pioneer the transformation of biomass residues into high-value biopolymers using groundbreaking green technologies.

This project assistant role offers a unique chance to drive innovation in sustainable biotechnology by transforming biomass residues into valuable biomolecules.

You will lead the extraction and characterization processes using cutting-edge chromatographic and green extraction techniques, directly influencing the quality and yield of molecules. Working with a diverse team in the Division of Industrial Biotechnology at Chalmers University of Technology, you will have access to state-of-the-art research infrastructure, enabling you to make a meaningful impact on sustainable resource management and ingredients production. 

About the research project 
A central focus in sustainable biotechnology research is increasing the efficiency of natural resource utilization while reducing waste generation.

This project is dedicated to valorizing side streams and residues from processed lignocellulosic biomass — transforming what is typically considered waste into valuable biopolymers. The structure and composition of these biomass residues play a key role in determining the yield and quality of the resulting macromolecules, opening up exciting opportunities for producing high-value biopolymers from wood-based materials.

As a project assistant, you will take an active role in the extraction and characterization of these bio-based fractions. You will apply advanced chromatographic methods along with environmentally friendly, green extraction techniques. Through your contributions, you will help advance innovative and sustainable approaches to resource management and circular bioeconomy.

About us
At the division of Industrial Biotechnology in the group of Assistant Prof. Amparo Jiménez Quero you will be working with a multidisciplinary and multicultural set of researchers with a broad background in biomass utilization, from enzymatic degradation to molecular characterization of biomass polymers. The IndBio division and WWSC (Wallenberg Wood Science Center) will provide access to large research infrastructure related to the project goals.


Who we are looking for
The successful candidate fulfils the following:


• A master's level degree corresponding to at least 240 higher education credits in Wood chemistry, Biotechnology or Biochemistry.
• Strong written and verbal communication skills in English.

While laboratory experience in biopolymer technology, biomass utilization, or analytical chemistry is considered an advantage, a strong motivation to work in a multidisciplinary PhD project is essential.

What you will do
As a project assistant, the main time of your working appointment is devoted to your research project where you will be responsible for planing, running experiments and evaluation the scientific outcome. You are also expected to communicate your results in different settings, group and division meetings at Chalmers but also external events such as workshop.

What we offer
Chalmers offers a dynamic and inspiring working environment in the coastal city of Gothenburg. Read more about working at Chalmers and our benefits for employees.

Chalmers is dedicated to improving gender balance and actively works with equality projects, such as the GENIE Initiative for gender equality and excellence. We celebrate diversity and consider equality and inclusion as fundamental aspects of all our activities.

Type of employment
This is a temporary employment of 360 days.

Application procedure
The application should be written in English be attached as PDF-files, as below. Maximum size for each file is 40 MB. Please note that the system does not support Zip files.


• CV: (Please name the document: CV, Family name)
• Personal letter (Please name the document: Personal letter, Family name, ref.number)


• 1-2 pages where you:
• Introduce yourself
• Describe your previous experience of relevance for the position (e.g. education, thesis work and, if applicable, any other research activities)
• Describe your future goals




Use the button at the foot of the page to reach the application form. 

Please note: The applicant is responsible for ensuring that the application is complete. Incomplete applications and applications sent by email will not be considered. Contact details for references will be requested after the interview.

Application deadline:  17th May 2025, however, applications will be reviewed on an ongoing basis and the position may be closed before deadline.

For questions, please contact: Assistant Prof. Amparo Jiménez Quero, [email protected]


We look forward to your application!


*** Chalmers declines to consider all offers of further announcement publishing or other types of support for the recruiting process in connection with this position. *** 
   


Chalmers University of Technology in Gothenburg conducts research and education in technology and natural sciences at a high international level. The university has 3100 employees and 10,000 students, and offers education in engineering, science, shipping and architecture. With scientific excellence as a basis, Chalmers promotes knowledge and technical solutions for a sustainable world. Through global commitment and entrepreneurship, we foster an innovative spirit, in close collaboration with wider society.
Chalmers was founded in 1829 and has the same motto today as it did then: Avancez – forward. Visa mindre

The University of Gothenburg tackles society’s challenges with diverse knowledge. 56 000 students and 6 600 employees make the university a large and inspiring place to work and study. Strong research and attractive study programmes attract researchers and students from around the world. With new knowledge and new perspectives, the University contributes to a better future.The Institute of Biomedicine is involved in both research and education. In both of these areas, we focus on fundamental knowledge of the living cell – what it consists of, how it works, how its function is directed by the genetic material, and how it interacts with various kinds of micro-organisms. Using this knowledge, we try to elucidate the causes of diseases, and find new ways to diagnose and treat them.

 

Subject area 
Cell biology.

 
Subject area description 
The project is focused on mechanisms that regulate initiation, growth and survival of ALK, a receptor tyrosine kinase, driven neuroblastoma.

 

Duties 
The researcher will be engaged in projects focused on mechanisms that regulate initiation, growth and survival of ALK, a receptor tyrosine kinase, driven neuroblastoma and their microenvironment. The researcher will use a broad range of approaches, such as genetics, cell biology but mostly in vivo mouse modeling to understand/reveal upstream/downstream targets of ALK both during novel developmental processes and disease. The researcher will be involved in mouse and cell culture models of ALK positive cancer to validate novel therapeutic strategies. Signaling pathways, such DNA Damage Response and salvage pathways, will be further investigated in these models with consideration of their pathological relevance.  We recently identified of the ALK ligands and development of mouse models of ALK driven NB together with BioID.  Further, our protocol combining ATR and ALK inhibition that leads to complete regression of NB tumours in our ALK-driven NB GEMMs have been acknowledged. PMID: 34819497 och 3815

 
Eligibility 
The eligibility criteria for employing teaching staff are set out in Chapter 4 of the Higher Education Ordinance and in the Appointment Procedure for Teaching Posts at the University of Gothenburg. 

 

To be eligible for appointment as a postdoc, the applicant is required to have a doctoral degree, a doctoral degree in art or a foreign degree that is deemed to be equivalent to a doctoral degree. This eligibility requirement must be met before the employment decision is made. 

In the first instance, those who have completed their degree no more than three years prior to the end of the application period shall be considered. Those who have completed their degree more than three years prior to the end of the application period may also be considered in the first instance if special grounds exist. Special grounds relate to leave of absence due to illness, parental leave, commissions of trust within union organisations, service within the defence services or other similar circumstances, as well as clinical service or service/assignment relevant to the subject area.  

 

Assessment criteria 
Xx PhD in a relevant subject, post-doc experience is meritorious. A high level of English communication and writing skills are an important requirement. The candidate is expected to be active in designing and implementing their projects, and also to collaborate closely with other members of the team. Methods employed require knowledge in genetics, cell biology, biochemistry, and histology. Knowledge with mouse models as well as knowledge working with cell culture systems is a requirement. Our different mouse models will be explored with “omics”, specifically phosphoproteomics technologies to address ALK function in real life and disease.  Laboratory knowledge and documented training regarding handling/working with mice and experience in xenografts is an absolute requirement. Drug treatment and screening, live imaging, knowledge of ultra sound imaging, MRI, biochemical assays, and cell culture model systems are an advantage.

Regulations for the evaluation of qualifications for academic positions are given in Chapter 4, Section 3 - 4 of the Higher Education Ordinance.

 

Employment 
The employment is full time and temporary, two years with the possibility of one year's extension, with placement at the Institute of Biomedicine. First day of employment as agreed.

 

Contact information 
If you have any questions about the position, please contact Professor Bengt Hallberg, phone +4631-7863815, mail [email protected]

 

Unions 
Union representatives at the University of Gothenburg can be found here:?https://www.gu.se/om-universitetet/jobba-hos-oss/hjalp-for-sokande 

 

 

Application 

Submit your application via the University of Gothenburg’s recruitment portal by clicking the “Apply” button. It is your responsibility to ensure that the application is complete as per the vacancy notice, and that the University receives it by the final application deadline.  

The application should contain:

- A cover letter giving a brief description of previous research experience, and a motivation to why you are applying

- A CV including a list of publications

- Contact details of two references¨

Proof of  completed small animal training course.

- Proof of completed PhD

Applications must be received by: 2025-02-04

 

? 

Information for International Applicants 

Choosing a career in a foreign country is a big step. Thus, to give you a general idea of what we and Gothenburg have to offer in terms of benefits and life in general for you and your family/spouse/partner please visit: 

https://www.gu.se/en/about-the-university/welcome-services 
https://www.movetogothenburg.com/ 

The University works actively to achieve a working environment with equal conditions, and values the qualities that diversity brings to its operations.

Salaries are set individually at the University.

In accordance with the National Archives of Sweden’s regulations, the University must archive application documents for two years after the appointment is filled. If you request that your documents are returned, they will be returned to you once the two years have passed. Otherwise, they will be destroyed.

In connection to this recruitment, we have already decided which recruitment channels we should use. We therefore decline further contact with vendors, recruitment and staffing companies. Visa mindre

Are you an experienced scientist with a flair for mathematical modelling and knowledge of pharmacokinetics and pharmacodynamics? Are you passionate about PKPD and model-based drug discovery? Would you like to apply your knowledge in a global company that follows the science and turns ideas into life-changing medicines? If you are ready to drive innovation and make meaningful impacts in the PKPD field, then you could be the new colleague we are looking for to be part of the development of future treatment within respiratory and immunology.

Working at AstraZeneca means being entrepreneurial, thinking big and working together to make the impossible a reality. We are now recruiting a highly skilled and passionate scientist with expertise in mathematical modelling, preferably applied in the field of pharmacokinetics-pharmacodynamics (PKPD), to join the Drug Metabolism and Pharmacokinetics (DMPK) team of project leads within the Early Respiratory and Immunology (R&I) therapeutic area at AstraZeneca in Gothenburg, Sweden.

Early R&I is one of the three main therapeutic research areas within AstraZeneca which deliver candidate drugs into late-stage clinical development. DMPK interacts with other functions in supporting Early R&I projects all along the value chain, from target selection all the way to market launch and life-cycle management. At AstraZeneca we are proud to have an outstanding workplace culture that encourages innovation and teamwork. We are united by our vision to push the boundaries of DMPK science to transform ideas into medicines for R&I patients.

This position will be on-site in Gothenburg, Sweden and will not have the ability to be located remotely. The position can be filled at Senior Scientist, Associate Principal Scientist or Principal Scientist level, depending on background, experience and skills.



What you'll do
As a PKPD Scientist you will be involved in many tasks related to PK and PKPD assessment, modelling and translation. You will represent the department in highly collaborative, cross-disciplinary project teams in early R&I across a broad range of drug modalities from target identification to life cycle management. We believe that you have solid, hands-on experience of PKPD modeling and that you will be able to provide expert advice and interpretation of complex drug discovery data.

Main Duties and Responsibilities include:
* Build appropriate mathematical models (e.g. traditional PKPD modelling, non-linear mixed effects modelling, quantitative systems pharmacology) and perform simulations of human PK and PD based on preclinical (in vitro/in vivo) data and literature data on relevant drugs to deliver a translational quantitative PKPD strategy in projects
* Integrate the appropriate data to predict human pharmacokinetics, efficacious human drug exposure, human longitudinal response (e.g. biomarker and disease effects), and human dosing regimen. This is done in close collaboration with other functions (biologists, safety scientists, clinical pharmacologist and clinical pharmacometricians)
* Inform and influence the design of preclinical PK and PKPD studies to answer relevant pharmacological questions and contribute to estimation of safety margins
* Report results and interpretations to project teams and communicate scientific progress to internal and external stakeholders

Essential for the role
* PhD/MSc in mathematics, pharmaceutical sciences, pharmacology, biomedical engineering, biochemistry, chemistry or related field, or equivalent experience in a relevant field and least 5 years' relevant experience
* Solid understanding of PKPD and hands on experience of mathematical modelling (e.g. empirical PKPD models, in vitro-in vivo translation, non-linear mixed effects models, quantitative systems pharmacology (QSP) models) and substantial relevant pharmaceutical industry experience

* Experience working in cross-functional project teams with a proactive and collaborative mindset and excellent communication skills
* Working knowledge of PKPD software (e.g. Phoenix WinNonlin, Matlab, R, NONMEM, or similar) and the ability to critically assess PKPD data
* Proven scientific leadership and ability to mentor junior colleagues
* Scientific leadership evidenced by a publication track record and ability to independently lead the drafting and review of publication manuscripts
* Excellent interpersonal skills

Why AstraZeneca?
As we know employees are critical to our current and future success, we are dedicated to being a great place to work and we offer competitive benefits and services. You are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There is no better place to make a difference to medicine, patients and society. AstraZeneca has an inclusive culture that champions diversity and collaboration - always committed to lifelong learning, growth and development.

What's next?
This is an exciting opportunity for a talented modeller to join a strong, dynamic team and support the portfolio of a major pharmaceutical company that has science at its heart whilst being based in the beautiful city of Gothenburg, Sweden.

If you are ready to make a difference - apply today, and we'll make it happen together! We welcome your application until 29 November, 2024. For more information about the position, please contact recruiting manager Nina Lawrence at [email protected]

Where can I find out more?
Our Gothenburg site: https://www.astrazeneca.com/our-science/gothenburg.html
Life in Gothenburg: https://www.movetogothenburg.com/
Culture and atmosphere of the Gothenburg site: https://www.linkedin.com/feed/update/urn:li:activity:6496327311678410752/
Relocate to Gothenburg: https://www.astrazeneca.se/om-oss/verksamheten-i-sverige/goteborg/relocate-to-gothenburg.html Visa mindre

12 Months Protein Structure & Biophysics – Student Work Placement
About AstraZeneca
AstraZeneca is a global, science-led biopharmaceutical business and its innovative medicines are used by millions of patients worldwide. AstraZeneca has long been an advocate of student work placement training. AstraZeneca considers its responsibility to help promising scientists develop into the researchers of the future, by immersing them in a world of practical science. This is achieved by aligning each student with a research team working on groundbreaking drug discovery projects. You will feel trusted and empowered to take on new challenges, but with all the help and guidance you need to succeed.
Introduction to role
The Protein Structure & Biophysics Student Work Placement Programme offers an outstanding 12-month opportunity to dive into the world of innovative drug discovery. At AstraZeneca, you will be part of a pioneering research and development organization, working on meaningful projects that push the boundaries of science to deliver life-changing medicines. This placement will help you develop essential skills, expand your knowledge, and build a network that will set you up for future success. You will be surrounded by curious, hard-working, and open-minded professionals eager to learn and grow in a truly collaborative and global team.
Accountabilities
We offer 12-month placements at AstraZeneca’s Gothenburg site in Sweden for students from Swedish institutions. The role will be within the Protein Science, Structural Biology, and Biophysics department in Discovery Sciences, specifically in the Molecular Biology and Expression team and the Membrane Protein Science team. Your responsibilities will include:
Generating DNA constructs for downstream drug applications.
Working on protein expression and purification for structure and biophysics.
Contributing to methods development to accelerate construct screening.
Engaging in complex plasmid construct design and high throughput cloning techniques.
Building experience with lab automation for molecular biology.
Learning and developing skills in eukaryotic protein expression and purification.

Essential Skills/Experience
Ongoing BSc or MSc studies in Bioscience or other relevant subjects, from a Swedish University.
Completion of at least two years of university education by the start of the placement, with plans to return to complete studies after the placement ends.
High academic performance with the potential to achieve a pass with distinction.
Eligibility to work in Sweden for 12 months from September 2025 without needing additional work permits.
Ability to arrange a study break from your university education to participate in the programme.

AstraZeneca is committed to encouraging an environment where everyone can thrive. Here, you will gain insight into what it’s really like to work in big biopharma, working on projects that have real patient impact. You will feel trusted and empowered to take on new challenges with all the support and guidance you need. Our collaborative and global team is dedicated to helping you get the most out of your time with us, ensuring you develop the skills, knowledge, and connections that will set you up for success. Join us and be part of a high-performing team driven by a shared purpose to push the boundaries of science and deliver life-changing medicines.
Additional Information:
Applications are now open until January 2025, with interviews to take place in March 2025. Start date 1st September 2025. Applications must be submitted in English.
Please inform us if you require adjustment support when contacted to schedule an interview – necessary adjustments can be made for assessment centers.
This internship is a collaboration between AstraZeneca and Kelly Services. The employment relationship is with Kelly Services partner, Poolia AB.
Ready to make a difference? Apply now and take the first step towards an exciting career in biopharma! Visa mindre

AstraZeneca is a major international healthcare business engaged in the research, development, manufacture and marketing of prescription pharmaceuticals and the supply of healthcare services. However, as a company they are more than one of the world's leading pharmaceutical companies, they are also proud to have a unique workplace culture that inspires innovation and collaboration.
KellyOCG are now searching for two "Research Scientists - Biosamples, Biobank" for contracts at AstraZeneca through KellyOCG. There is one longer contract (a full year), and one shorter (around 7 months long). Both have opportunities of extension and further future collaborations.

The arena:
Biobank scientists are responsible for the storage and timely supply of human biological samples (HBS) to AZ research projects. HBS are received from e.g. clinical studies or academic collaborations, stored in local biobanks and distributed to projects. The group primarily supports the Sweden Region but partners with other Biobank groups within AZ globally to provide efficient support across AZ and our partner organizations.
The Biobank group works collaboratively to provide support within agreed service levels with a strong focus on our customers. We strive hard to understand what fits their needs best and to add value through our services. With an increased focus on the value and use of biobank samples we actively seek ways to improve our process or exploit new technology to build a cutting-edge facility.

Tasks and responsibilities/The role:
We are currently recruiting for a Biobank Scientist in the AZ Gothenburg Biobank group within the global Precision Medicine and Biosamples organization. This position will provide the opportunity to work in a dynamic and enthusiastic environment whilst supplying a critical service to drug discovery projects. The work is highly collaborative with the team having a collective responsibility for the overall delivery.
The role is focused on supporting drug discovery projects within R&D Gothenburg by maintaining high quality handling and storage of HBS and support projects with requested samples in a timely manner.

As a Biobank Research Scientist you will be expected to:
• Receive and register incoming HBS
• Process requests for HBS to customers, including using automated liquid handler
• Manage customer orders using specialized informatics systems as well as databases and respond to customer queries via mail or telephone
• Partner with Biobank groups globally as well as internal and external customers
• Act upon day-to-day issues that occur whilst processing HBS samples to ensure continuous improvement
The group has a strong emphasis on continuous improvement which takes the form of individual and group projects within the team, the department and across Biobank groups within AZ.

Requirements:
Essential for the role:
• University degree in a Bioscience discipline and previous experience of laboratory work handling biological samples.
• Previous knowledge and experience (1 year) of biobanking is highly desirable.
• Experience of working with various IT solutions, including extensive knowledge of Excel, LIMS systems and database usage, is also a clear advantage.
• Experience of automated liquid handling is advantageous.
• Good analytical and problem-solving skills involving large and complex datasets is desirable.
• Excellent English, both spoken and written

Desirable:
• Knowledge of the regulatory framework of biological samples.
• Interest in logistics and developing processes through customer interactions and technology awareness.
• Drive and enthusiasm to solve the root cause of problems and not only overcome the presenting problem.
• Thrive on working in a committed team and gain satisfaction from the overall performance of the group
The biobank team is a highly collaborative group working to tight delivery schedules so the ability to be comfortable working at a fast pace with a goal orientated and team focused attitude is essential. Excellent communication skills with a proactive and service minded approach is key.

Final date to apply is September 5th. We utilize a continuous selection and interviews, and the positions might be filled before the deadline. So should you find the positions interesting, don't wait to send in your application!
AstraZeneca is one of the world’s most exciting bio-pharmaceutical companies. From scientists to sales, lab techs to legal, we’re on a mission to turn ideas into life-changing medicines that improve patients’ lives and benefit society. We need great people who share our passion for science and have the drive and determination to meet the unmet needs of patients around the world. Visa mindre

Research Scientist Biosamples, Biobank Scientist - Consultancy role for AstraZeneca

AstraZeneca is a major international healthcare business engaged in the research, development, manufacture and marketing of prescription pharmaceuticals and the supply of healthcare services. However, as a company we are more than one of the world's leading pharmaceutical companies, we are proud to have a unique workplace culture that inspires innovation and collaboration. AstraZeneca employees are empowered to express diverse perspectives - and are made to feel valued, energized and rewarded for their ideas and creativity.

The arena:
Biobank scientists are responsible for the storage and timely supply of human biological samples (HBS) to AZ research projects. HBS are received from e.g. clinical studies or academic collaborations, stored in local biobanks and distributed to projects. The group primarily supports the Sweden Region but partners with other Biobank groups within AZ globally to provide efficient support across AZ and our partner organisations.

The Biobank group works collaboratively to provide support within agreed service levels with a strong focus on our customers. We strive hard to understand what fits their needs best and to add value through our services. With an increased focus on the value and use of biobank samples we actively seek ways to improve our process or exploit new technology to build a cutting-edge facility.

Tasks and responsibilities/The role:
We are currently recruiting for a Biobank Scientist in the AZ Gothenburg Biobank group within the global Precision Medicine and Biosamples organization. This position will provide the opportunity to work in a dynamic and enthusiastic environment whilst supplying a critical service to drug discovery projects. The work is highly collaborative with the team having a collective responsibility for the overall delivery.

The role is focused on supporting drug discovery projects within R&D Gothenburg by maintaining high quality handling and storage of HBS and support projects with requested samples in a timely manner.

As a Biobank Research Scientist you will be expected to:
-Work as part of the team rotating between the following typical tasks
-Receive and register incoming HBS
-Process requests for HBS to customers, including using automated liquid handler
-Manage customer orders using specialized informatics systems as well as databases
-Respond to customer queries via mail or telephone
-Partner with Biobank groups globally as well as internal and external customers
-Work closely with other groups in the organization
-Act upon day-to-day issues that occur whilst processing HBS samples to ensure continuous improvement
-Identify initiatives to improve efficiency or quality.

The group has a strong emphasis on continuous improvement which takes the form of individual and group projects within the team, the department and across Biobank groups within AZ.

The biobank team is a highly collaborative group working to tight delivery schedules so the ability to be comfortable working at a fast pace with a goal orientated and team focussed attitude is essential. Excellent communication skills with a proactive and service minded approach is key.

AstraZeneca is one of the world's most exciting bio-pharmaceutical companies. From scientists to sales, lab techs to legal, we're on a mission to turn ideas into life-changing medicines that improve patients' lives and benefit society. We need great people who share our passion for science and have the drive and determination to meet the unmet needs of patients around the world.



What you need to do now

If you're interested in this role, click 'apply now' to forward an up-to-date copy of your CV, or call us now.

If this job isn't quite right for you, but you are looking for a new position, please contact us for a confidential discussion on your career. Visa mindre

Göteborgs universitet möter samhällets utmaningar med mångsidig kunskap. 56 000 studenter och 6 600 medarbetare gör universitetet till en stor och inspirerande arbetsplats. Stark forskning och attraktiva utbildningar lockar forskare och studenter från hela världen. Med ny kunskap och nya perspektiv bidrar Göteborgs universitet till en bättre framtid.Vid Institutionen för neurovetenskap och fysiologi vid Sahlgrenska akademin bedrivs omfattande forskning och undervisning över stora kunskapsområden från molekyl till människa. Verksamheten utgörs av fem sektioner; farmakologi, fysiologi, hälsa och rehabilitering, klinisk neurovetenskap samt psykiatri och neurokemi.

Institutionen för neurovetenskap och fysiologi, söker nu en postdoktor, med placering vid Sektionen för psykiatri och neurokemi.

Vid Sektionen för psykiatri och neurokemi inom Institutionen för neurovetenskap och fysiologi bedrivs neurokemisk forskning med inriktning att identifiera och studera patofysiologi och patologier vid neurodegenerativa sjukdomar.

Ämne
Neurokemi 

Ämnesbeskrivning
Den aktuella forskargruppen utvecklar och studerar kroppsvätskebaserade biomarkörer för neurodegenerativa sjukdomar såsom Alzheimers sjukdom, Lewykroppsdemens, Parkinsons sjukdom och pannlobsdemens.

Arbetsuppgifter
Anställningen innebär att utveckla och validera nya kroppsvätskebaserade biomarkörer för neurodegenerativa sjukdomar genom masspektrometriska och immunokemiska mätmetoder, med särskilt fokus på standardisering av mätmetoder för neurofilament light polypeptide (Nfl). Dessutom ingår att i anställningen handleda studenter och doktorander, delta i konferenser, ansöka om forskningsanslag, delta i doktorandutbildningar, med mera. Vi letar efter en kollega som har mycket hög kompetens inom dessa områden och som är mycket motiverad, vetenskapligt oberoende och kreativ, liksom kapabel och intresserad av att bidra till en tvärvetenskaplig teammiljö. 

Behörighet
Behörighet för anställning som lärare regleras i Högskoleförordningen 4 Kap och Göteborgs universitets anställningsordning. 

Behörig att anställas som postdoktor är den som har avlagt doktorsexamen, konstnärlig doktorsexamen eller som har en utländsk examen som bedöms motsvara doktorsexamen. Detta behörighetskrav ska vara uppfyllt senast vid tidpunkten då anställningsbeslutet fattas.

I första hand bör den komma i fråga som har avlagt examen högst tre år före ansökningstidens utgång. Även den som avlagt examen tidigare bör komma i fråga i första hand, om det finns särskilda skäl. Med särskilda skäl avses ledighet på grund av sjukdom, föräldraledighet, förtroendeuppdrag inom fackliga organisationer, tjänstgöring inom totalförsvaret, eller andra liknande omständigheter samt klinisk tjänstgöring eller för ämnesområdet relevant tjänstgöring/uppdrag.

Behörig att anställas som postdoktor för denna utlysning är den som innehar doktorsexamen i analytisk kemi, biokemi, neurovetenskap, medicinsk forskning, biomedicinsk teknik eller liknande.

Bedömningsgrund
För att kvalificera sig som postdoktor måste den sökande ha avslutat en svensk doktorsexamen eller ha en utländsk examen motsvarande en svensk doktorsexamen. En vetenskaplig bakgrund inom kemi, biokemi, eller neurokemi är meriterande. Teoretiska och praktiska kunskaper inom masspektrometriska mätmetoder är önskvärda.

Vi lägger stor vikt vid personlig lämplighet. 

Anställning
Anställningen är en tidsbegränsad anställning i 2 år, 100% av heltid, med placering tills vidare vid Institutionen för neurovetenskap och fysiologi. Tillträde: snarast eller enligt överenskommelse.  

Kontaktuppgifter för anställningen
Har du frågor om anställningen är du välkommen att kontakta forskare Johan Gobom, tfn: +46 730 229 028, e-post: [email protected]

Ansvarig chef är professor/sektionschef Henrik Zetterberg, tfn: +46 768 672 647, e-post: [email protected]

Ansökningshandlingar skickas inte till kontaktpersonerna.

Fackliga organisationer
Fackliga företrädare vid Göteborgs universitet hittar du här: ?https://www.gu.se/om-universitetet/jobba-hos-oss/hjalp-for-sokande

Ansökan
Du söker anställningen via Göteborgs universitets rekryteringsportal genom att registrera din ansökan elektroniskt via hemsidan: https://www.gu.se/jobba-hos-oss/lediga-anstallningar

Du som sökande ansvarar för att ansökan är komplett i enlighet med annonsen och att den är universitetet tillhanda senast sista ansökningsdag. 

Intyg om doktorsexamen bifogas med ansökan.

Ansökan ska vara inkommen senast: 2024-07-15

Universitetet arbetar aktivt för en arbetsmiljö med jämställda förhållanden och sätter värde på de kvalitéer mångfald tillför verksamheten.

Universitetet tillämpar individuell lönesättning.

Enligt Riksarkivets föreskrifter är universitetet skyldigt att förvara ansökningshandlingar i två år efter tillsättningsbeslutet. Om du som sökande till en anställning särskilt begär tillbaka dina handlingar återsänds de när de två åren har förflutit, i annat fall kommer de att gallras ut.

Till bemannings- och rekryteringsföretag och till dig som är försäljare: Göteborgs universitet anlitar upphandlad annonsbyrå i samband med rekrytering av personal. Vi undanber oss vänligen men bestämt direktkontakt med bemannings- och rekryteringsföretag samt försäljare av jobbannonser. Visa mindre

Göteborgs universitet möter samhällets utmaningar med mångsidig kunskap. 56 000 studenter och 6 600 medarbetare gör universitetet till en stor och inspirerande arbetsplats. Stark forskning och attraktiva utbildningar lockar forskare och studenter från hela världen. Med ny kunskap och nya perspektiv bidrar Göteborgs universitet till en bättre framtid.Institutionen för kemi och molekylärbiologi bedriver högkvalitativ forskning och utbildning inom kemiska vetenskaper och molekylära livsvetenskaper. Vår forskning och utbildning fokuserar på en djup förståelse av kemiska och biologiska processer i celler och i miljön. Vi tar oss an viktiga samhällsfrågor som till exempel antibiotikaresistens, cancer, hjärnsjukdomar, miljöproblem och klimatförändringar. På så sätt medverkar vi till att uppnå FN:s globala mål för hållbar utveckling inom områdena god hälsa och välbefinnande, hållbar energi för alla, hållbara städer och samhällen samt bekämpa klimatförändringar. Institutionen är en internationell miljö med tvärvetenskapliga samarbeten inom både forskning och utbildning, och bidrar starkt till Göteborgs universitets topprankning inom life science. Institutionen ansvarar för forskarutbildning inom ämnesområdet Naturvetenskap med inriktning mot kemi, biofysik, biologi och utbildningsvetenskap. Därtill är institutionen värd för utbildningsprogram i molekylärbiologi, genomik och systembiologi, kemi, organisk kemi och läkemedelskemi samt receptarieutbildningen. Institutionen samverkar med olika samhällsaktörer som skolor, näringsliv och myndigheter. Institutionen för kemi och molekylärbiologi har runt 250 anställda. Vi finns i centrala nybyggda lokaler, Natrium, på Campus Medicinareberget i Göteborg. 

’Protein Production Sweden (PPS)’ är en ny nationell infrastruktur med finansiering från Vetenskapsrådet i syfte att koordinera och utföra produktion av proteiner i olika expressionssystem för svenska forskare. Koordineringen av aktiviteterna vid fem universitet i Sverige kommer att ge en ökad tillgänglighet och kompetens inom proteinproduktion och kommer att säkra service av hög kvalitet inom området. Tjänsten är delad mellan ’Yeast Protein Production (YPP)’ och ’Mammalian Protein [removed]MPE)’ faciliteterna vilka båda är delar av PPS. YPP fokuserar på produktion av alla sorts proteiner i jästen Pichia pastoris, intracellulärt eller sekreterat, och MPE fokuserar på produktion av proteiner och glykoproteiner i mammalieceller. Både enheterna är resurscenters som ger forskningsservice när det gäller produktion och rening av rekombinanta proteiner där avancerad utrustning och kvalificerad kompetens utgör naturliga mötesplatser för nationella och internationella kontakter inom livsvetenskaperna. Med stöd från Vetenskapsrådet till PPS söker vi nu en erfaren proteinkemist för produktion och rening av proteiner från både jäst- och mammalieceller.

Arbetsuppgifter: 

Ett nyckelfokus för tjänsten är att driva och ansvara för proteinproduktionsprojekt för olika forskare. Arbetet är labbaserat och innebär att transformera och odla jästceller, odla och transfektera mammalieceller, proteinrening, karakterisering och kvalitetskontroll. Detta innefattar planering och utförande av olika typer av cellkulturer, vilket inkluderar stor- och småskaliga transfektioner och bioreaktorkulturer, rening och produktion av proteiner samt olika proteinanalyser. Molekylärbiologiskt arbete och kloning kan också ingå, där en väsentlig del är att vara rådgivande i design av konstrukt utifrån användarnas forskningsfrågeställning. Kommunikation med olika forskare och rapportering av projekt är viktiga delar av arbetet, liksom att upprätthålla rutinerna på de båda faciliteterna. Arbetstiden kommer att fördelas lika mellan de två olika faciliteterna. Arbetet utförs självständigt eller tillsammans med andra gruppmedlemmar och kräver flexibilitet samt förmågan att anpassa sig till olika uppgifter. Helgarbete kan förekomma. Tjänsten kräver professionellt kunnande samt erfarenhet av proteinproduktion samt förståelse för både proteinkemi och den akademiska miljön. Det är viktigt att kunna utföra experiment baserat på forskares vetenskapliga krav på ett tidseffektivt och kvalitetsmedvetet sätt.

 

För mer information; var god och ansöker via https://www.gu.se/om-universitetet/jobba-hos-oss/lediga-anstallningar

Universitetet arbetar aktivt för en arbetsmiljö med jämställda förhållanden och sätter värde på de kvalitéer mångfald tillför verksamheten.

Universitetet tillämpar individuell lönesättning.

Enligt Riksarkivets föreskrifter är universitetet skyldigt att förvara ansökningshandlingar i två år efter tillsättningsbeslutet. Om du som sökande till en anställning särskilt begär tillbaka dina handlingar återsänds de när de två åren har förflutit, i annat fall kommer de att gallras ut.

Till bemannings- och rekryteringsföretag och till dig som är försäljare: Göteborgs universitet anlitar upphandlad annonsbyrå i samband med rekrytering av personal. Vi undanber oss vänligen men bestämt direktkontakt med bemannings- och rekryteringsföretag samt försäljare av jobbannonser. Visa mindre

Göteborgs universitet möter samhällets utmaningar med mångsidig kunskap. 56 000 studenter och 6 600 medarbetare gör universitetet till en stor och inspirerande arbetsplats. Stark forskning och attraktiva utbildningar lockar forskare och studenter från hela världen. Med ny kunskap och nya perspektiv bidrar Göteborgs universitet till en bättre framtid. 

Information om anställningen hittar du på Göteborgs universitets websida:

https://web103.reachmee.com/ext/I005/1035/job?site=6&lang=SE&validator=3038fcf1516ea1184a6da70a891f87da&job_id=33492

 

 

Du ansöker via https://www.gu.se/om-universitetet/jobba-hos-oss/lediga-anstallningar

 

Universitetet arbetar aktivt för en arbetsmiljö med jämställda förhållanden och sätter värde på de kvalitéer mångfald tillför verksamheten.

Universitetet tillämpar individuell lönesättning.

Enligt Riksarkivets föreskrifter är universitetet skyldigt att förvara ansökningshandlingar i två år efter tillsättningsbeslutet. Om du som sökande till en anställning särskilt begär tillbaka dina handlingar återsänds de när de två åren har förflutit, i annat fall kommer de att gallras ut.

Till bemannings- och rekryteringsföretag och till dig som är försäljare: Göteborgs universitet anlitar upphandlad annonsbyrå i samband med rekrytering av personal. Vi undanber oss vänligen men bestämt direktkontakt med bemannings- och rekryteringsföretag samt försäljare av jobbannonser. Visa mindre

Göteborgs universitet möter samhällets utmaningar med mångsidig kunskap. 56 000 studenter och 6 600 medarbetare gör universitetet till en stor och inspirerande arbetsplats. Stark forskning och attraktiva utbildningar lockar forskare och studenter från hela världen. Med ny kunskap och nya perspektiv bidrar Göteborgs universitet till en bättre framtid. 

Information om anställningen hittar du på Göteborgs universitets websida:

https://web103.reachmee.com/ext/I005/1035/job?site=6&lang=SE&validator=3038fcf1516ea1184a6da70a891f87da&job_id=34091

 

Du ansöker via https://www.gu.se/om-universitetet/jobba-hos-oss/lediga-anstallningar

 

Universitetet arbetar aktivt för en arbetsmiljö med jämställda förhållanden och sätter värde på de kvalitéer mångfald tillför verksamheten.

Universitetet tillämpar individuell lönesättning.

Enligt Riksarkivets föreskrifter är universitetet skyldigt att förvara ansökningshandlingar i två år efter tillsättningsbeslutet. Om du som sökande till en anställning särskilt begär tillbaka dina handlingar återsänds de när de två åren har förflutit, i annat fall kommer de att gallras ut.

Till bemannings- och rekryteringsföretag och till dig som är försäljare: Göteborgs universitet anlitar upphandlad annonsbyrå i samband med rekrytering av personal. Vi undanber oss vänligen men bestämt direktkontakt med bemannings- och rekryteringsföretag samt försäljare av jobbannonser. Visa mindre

Scientist In vivo Bioscience - AstraZeneca - Göteborg - 7 months

We are now looking for a Scientist to join the In vivo Bioscience team within Research and Early Development, Respiratory & Immunology in Gothenburg, Sweden.

Respiratory & Immunology is one of AstraZeneca's main therapy areas. From a research perspective we work to understand, treat, modify and ultimately cure respiratory and autoimmune diseases. In this role, you will focus on mouse models of inflammatory bowel disease (IBD).

Key Duties and Responsibilities:
As part of the team, you will plan, execute and analyse ex vivo samples generated from in vivo studies to progress our drug discovery projects and generate publishable scientific insights. You will actively take part in scientific discussions to add valuable inputs in experimental design and data interpretation.

This is a mainly lab-based role where you will be involved in ongoing projects focusing on pre-clinical experiments.

What you'll do:
* As a Scientist you will be a vital member of the in vivo community and will contribute to the development and characterization of pre-clinical models of IBD to discover novel therapeutics.
* You will contribute to the analysis of in vivo studies with a specific focus on FACS analysis. ntial discussion on your career. Visa mindre

Göteborgs universitet möter samhällets utmaningar med mångsidig kunskap. 56 000 studenter och 6 600 medarbetare gör universitetet till en stor och inspirerande arbetsplats. Stark forskning och attraktiva utbildningar lockar forskare och studenter från hela världen. Med ny kunskap och nya perspektiv bidrar Göteborgs universitet till en bättre framtid.För mer information, se   https://www.gu.se/om-universitetet/jobba-hos-oss/lediga-anstallningar

 

Universitetet arbetar aktivt för en arbetsmiljö med jämställda förhållanden och sätter värde på de kvalitéer mångfald tillför verksamheten.

Universitetet tillämpar individuell lönesättning.

Enligt Riksarkivets föreskrifter är universitetet skyldigt att förvara ansökningshandlingar i två år efter tillsättningsbeslutet. Om du som sökande till en anställning särskilt begär tillbaka dina handlingar återsänds de när de två åren har förflutit, i annat fall kommer de att gallras ut.

Till bemannings- och rekryteringsföretag och till dig som är försäljare: Göteborgs universitet anlitar upphandlad annonsbyrå i samband med rekrytering av personal. Vi undanber oss vänligen men bestämt direktkontakt med bemannings- och rekryteringsföretag samt försäljare av jobbannonser. Visa mindre

The University of Gothenburg tackles society’s challenges with diverse knowledge. 56 000 students and 6 600 employees make the university a large and inspiring place to work and study. Strong research and attractive study programmes attract researchers and students from around the world. With new knowledge and new perspectives, the University contributes to a better future. 

Subject area 
Structure determination of membrane proteins using cryo-EM.

 
Subject area description 
G protein-coupled receptors (GPCRs) are key transmembrane proteins that serve to transduce external stimuli to signals across the membrane and they constitute about 30-40% of all therapeutic drug targets. GPCRs are inherently allosteric and interact via distinct domains with both endogenous and synthetic compounds, proteins, metabolites, hormones and small molecules. Methodological breakthroughs have accelerated structure determination of GPCRs, however our understanding of the molecular basis of signaling complexes remain elusive.  We will characterize these complexes using structural, biophysical and pharmacological methods.

 

Duties 
The successful candidate will work on the structure and function of select GPCR signaling complexes using a combination of structural, biochemical and pharmacological approaches. The candidates will be encouraged and expected to conduct their research independently and to plan and execute research tasks in a timely manner. The candidates are also expected to travel for data collection purposes and to participate in collaborations with other research groups (either within Sweden or abroad). Additionally, the candidates may also be asked to assist in supervision of Master’s or doctoral students.

 
Eligibility 
The eligibility criteria for employing teaching staff are set out in Chapter 4 of the Higher Education Ordinance and in the Appointment Procedure for Teaching Posts at the University of Gothenburg. 

To be eligible for appointment as a postdoc, the applicant is required to have a doctoral degree, a doctoral degree in art or a foreign degree that is deemed to be equivalent to a doctoral degree. This eligibility requirement must be met before the employment decision is made. 

In the first instance, those who have completed their degree no more than three years prior to the end of the application period shall be considered. Those who have completed their degree more than three years prior to the end of the application period may also be considered in the first instance if special grounds exist. Special grounds relate to leave of absence due to illness, parental leave, commissions of trust within union organisations, service within the defence services or other similar circumstances, as well as clinical service or service/assignment relevant to the subject area. 

 

Assessment criteria 
We are looking for candidates with an interest in signaling, structural biology or pharmacology. The applicants must have a PhD in a relevant area of research such as medicine/biology/chemistry/pharmacology or related fields (for example structural biology, biochemistry or biophysics). The successful candidates should have extensive experience in cell cultivation (preferably eukaryotic cells), signaling, interaction studies as well as protein purification. Great emphasis will be placed on the candidate’s personal suitability for the position and interest in the subject area as well as their long-term research goals. The work involves close collaborations with other researchers and thus demands flexibility and a willingness to travel for data collection purposes.  Excellent communication skills (spoken and written) in English are a prerequisite for the position.

 

Regulations for the evaluation of qualifications for academic positions are given in Chapter 4, Section 3 - 4 of the Higher Education Ordinance.

 

Employment 
The employment is full time and temporary, two years with the possibility of one year's extension, with placement at the Institute of Biomedicine. First day of employment as agreed.

 

Selection process 
Help for applicants.

 

Contact information 
If you have any questions about the position, please contact Linda Johansson; email: [email protected]; telephone: +46(0)766183244.

 

Unions 
Union representatives at the University of Gothenburg can be found here:?https://www.gu.se/om-universitetet/jobba-hos-oss/hjalp-for-sokande 

 

 

Application 

Submit your application via the University of Gothenburg’s recruitment portal by clicking the “Apply” button. It is your responsibility to ensure that the application is complete as per the vacancy notice, and that the University receives it by the final application deadline.  

The application should contain:

- A cover letter giving a brief description of previous research experience, and a motivation to why you are applying

- A CV including a list of publications

- Proof of completed PhD

- Contact details of two references

Applications must be received by: 2024-04-30

 

? 

Information for International Applicants 

Choosing a career in a foreign country is a big step. Thus, to give you a general idea of what we and Gothenburg have to offer in terms of benefits and life in general for you and your family/spouse/partner please visit: 

https://www.gu.se/en/about-the-university/welcome-services 
https://www.movetogothenburg.com/ 

The University works actively to achieve a working environment with equal conditions, and values the qualities that diversity brings to its operations.

Salaries are set individually at the University.

In accordance with the National Archives of Sweden’s regulations, the University must archive application documents for two years after the appointment is filled. If you request that your documents are returned, they will be returned to you once the two years have passed. Otherwise, they will be destroyed.

In connection to this recruitment, we have already decided which recruitment channels we should use. We therefore decline further contact with vendors, recruitment and staffing companies. Visa mindre

Are you a passionate scientist, eager to join a company at the forefront of sample management technologies? Would you like to contribute to the continuous improvement of life-changing projects? Perfect, we have a new challenge for you!

We are looking for a motivated and engaged team member for our Compound Management team to join us as a Research Scientist at our vibrant R&D site at AstraZeneca in Gothenburg, Sweden.

In this role you will be responsible for the storage and timely supply of chemical compounds to AstraZeneca's drug discovery projects. Highly automated liquid handling systems will be employed to supply molecules to AstraZeneca scientists and partner organisations. You will be a part of the Discovery Sciences organisation, operating within a first-class scientific environment to support drug discovery across each of AstraZeneca's Therapeutic Areas.

This is a chance to thrive in a place where the brightest and most curious minds seamlessly come together in our inclusive environment.

What you will do:

In this position, you will get the opportunity to work in a dynamic and enthusiastic environment, whilst delivering critical support to all phases of drug discovery projects and working with a broad

range of chemical modalities. You will be supporting projects by providing compounds in the requested format - assay ready plates, serially diluted mother plates, formulations and solids. Bringing in new capabilities and building new processes are core activities within our group, performed in a cross-functional collaboration setting with the drug discovery projects.

You are expected to act upon day-to-day issues that occur whilst processing samples and run Compound Management development projects to ensure continuous improvement within the local team and the global department.



Examples of typical tasks are:

*

Designing, performing and interpreting experiments independently to investigate process improvements and evaluate new technologies.
*

Working closely with internal project teams to meet drug discovery needs.
*

Rapidly addressing customer queries with regards to Compound Management orders, software, processes and capabilities.
*

Achieving personal scientific visibility through project contributions, internal presentations and publications.



We work collaboratively within our Compound Management team to understand the customer needs and how to add value through our experience and capabilities. To maintain this position and provide support within agreed service levels, we actively seek ways to improve our process and exploit new technologies.



Essential for the role:

Compound Management is a highly collaborative group, working with tight delivery schedules - so the ability to be comfortable working at a fast, goal-oriented pace, with a team-focused attitude, is essential to being successful in the role. Furthermore, you have excellent communication skills with a proactive delivery and customer-focused approach.

We also believe that you have:

*

A BSc/MSc in Chemistry/Biotechnology/Chemical engineering, with relevant experience.
*

Excellent problem-solving skills and ability to identify and implement improvement activities.
*

A track record in the performance of a range of practical skills, including non-routine complex tasks, to a high level.



We also believe that our new colleague shares our passion for science, technology and innovation and has an understanding of the drug discovery process. Previous experience of working in a compound management role and operating integrated automation equipment like liquid handlers and scheduling software is beneficial but not required. Some experience with IT (/Python/Java coding) is an advantage but not a requirement.



Why AstraZeneca?
Here we are committed to making a difference. We have built our business around our passion for science. Now we are fusing data and technology with the latest scientific innovations to

achieve the next wave of breakthroughs.

So, what's next? If your passion is science and want to be a part of a team that makes a bigger impact on patient's lives, then there is no better place to be.

We look forward to getting to know you and invite you to submit your application as soon as possible but no later than the 10th of December 2023. Applications will be reviewed continuously.

For more information about the position please contact Maria Vergou, Associate Director at [email protected].

Additional information:
Our Gothenburg site: https://www.astrazeneca.com/our-science/gothenburg.html
Life in Gothenburg: https://www.movetogothenburg.com/
Make a move to Global Gothenburg: https://www.youtube.com/watch?v=c-Iqbb4aw38
About BioPharmaceuticals R&D: https://www.astrazeneca.com/r-d.html Visa mindre

Are you excited about Precision Medicine? Would you like have an impact on patients' lives and contribute to eliminate cancer as a cause of death? If so then join us!

We're investing like never before in our people, in growth, and in new diagnostic techniques and technologies. There are opportunities at every turn, with a variety and breadth that is uncommon to find and an industry-leading pipeline in oncology. Scientists at AstraZeneca are working every day to turn science fiction into science fact. Our ambition - to develop innovative, targeted medicines for every patient that needs them - and to match those treatments to patients most likely to benefit from them - is now a reality. This approach, known as Precision Medicine, is based on those individual characteristics that make some patients respond to treatment better than others. We use this knowledge to develop diagnostic tests that doctors can use to help prescribe the best treatment for each patient. Indeed, it's now become common practice for patients with cancer to be offered such diagnostic tests before their treatment plan is agreed.

The AstraZeneca Companion Diagnostics Unit within the Precision Medicine and Biosamples function drives scientific leadership through the delivery of innovative companion diagnostics enabling our oncology ambition to transform the lives of patients living with cancer, and ultimately eliminate cancer as a cause of death.

We do this by:

*

Leading the development of diagnostics across AstraZeneca's early and late stage oncology portfolios through close collaborations with our external diagnostic partners.
*

Leading the development and implementation of patient selection strategies to deliver companion diagnostics programs in support of our business priorities.
*

Leading companion diagnostic regulatory interactions to secure companion diagnostic approvals in major markets
*

Collaborate across AstraZeneca with colleagues in multiple Clinical functions plus commercial to help drive market uptake.
*

Developing strategies for early cancer detection, near patient testing and implementing testing options for minimal residual disease and early treatment interventions.
*

Utilising artificial intelligence diagnostic solutions and seeing software as a medical device.
*

Developing specific disease area strategies (e.g. lung cancer, breast cancer or hematological malignancies) and new diagnostic modalities.
*

Collaborating closely with fellow pharma companies on joint assets.

Join this fantastic, collaborative team and be part of our success; we have already delivered over 50 innovative/impactful companion/complementary oncology diagnostic approvals across the major markets of the US, EU, Japan and China since 2014 and we need you to help us take the next steps in patient-centric diagnostic development.

If this sounds like the type of organisation where you would like to grow your career and make a real difference to patients then we would like to hear from you.

Locations: Gothenburg Sweden, Warsaw Poland, Barcelona Spain, or Mississauga, Canada.

What you'll do:
As a Director, you'll be a member of the Oncology Companion Diagnostic Unit (CDU). Your objective will be to ensure that innovative companion diagnostic tests or equivalent segmentation tools are delivered to our oncology drug projects. Drawing on world-class expertise and personal experience in companion diagnostic development you will ensure the adoption of Precision Medicine approaches within the AstraZeneca business. You will also provide leadership and support to a pool of fellow diagnostic experts to ensure delivery of a diagnostic strategy.

This will entail developing and implementing the diagnostic strategy agreed by the respective development teams, and planning and leading Precision Medicine activities from a technical, financial, risk, regulatory, IP and partnering perspective. You will work collaboratively with colleagues at all levels in the Precision Medicine function to deliver this expertise to drug project teams.

Your role will also involve contributing to the personal development of project team members. Providing expert advice on strategic and innovative Precision Medicine approaches and companion diagnostic developments to development teams, you'll be instrumental in ensuring that we adopt world-class practice in the field.

Essential:

*

PhD or equivalent experience in a relevant subject.
*

Experience of companion diagnostic tests or patient biomarker/segmentation tools in clinical development.
*

Experience of Precision Medicine approaches and diagnostic development within the relevant therapeutic area.
*

Effective communication, stakeholder, influencing skills and programme management.

*

Significant understanding of the functions involved in companion diagnostic development and how they contribute to achieving successful diagnostic submissions and approvals

Desirable :

*

Significant previous experience in a similar role in different companies.
*

Delivery of companion diagnostics, regulatory interactions and commercialisation.
*

High quality scientific expertise in the field of Precision Medicine or relevant therapeutic area as evidenced by publications.

If this sounds like the type of organisation where you would like to grow your career and make a real difference to patients then we would like to hear from you; apply today! Visa mindre

Göteborgs universitet möter samhällets utmaningar med mångsidig kunskap. 56 000 studenter och 6 600 medarbetare gör universitetet till en stor och inspirerande arbetsplats. Stark forskning och attraktiva utbildningar lockar forskare och studenter från hela världen. Med ny kunskap och nya perspektiv bidrar Göteborgs universitet till en bättre framtid.Core Facilities är en öppen universitetsgemensam forskningsinfrastruktur för forskning inom Life Science. Vi finns på Sahlgrenska akademin, Göteborgs universitet, och erbjuder tillgång till några av Sveriges mest avancerade tekniker och analysverktyg för forskning inom t.ex. medicin, biomedicin och kliniska studier. Alla våra enheter har stark nationell och internationell profil och vi är del av bland annat SciLifeLab.  Enheterna vid Core Facilities är utrustade med avancerade instrument och specialiserade experter med hög kompetens. Utöver högklassigt forskningsstöd erbjuder vi också teoretisk utbildning och praktiska kurser. Vår infrastruktur är öppen för alla forskare – både vid Göteborgs universitet och vid andra lärosäten och privat industri i Sverige och internationellt.

Center for Cellular Imaging (CCI), som etablerades 2003, är en nationell forskningsinfrastruktur och en av Sveriges ledande akademiska mikroskopifaciliteter. Här erbjuds tillgång till expertis och avancerade mikroskop för hela forskarsamhället, både lokalt, nationellt och internationellt. (https://www.gu.se/en/core-facilities/centre-for-cellular-imaging). CCI tillhör Core Facilities vid Göteborgs universitet och är också del av National Microscopy Infrastructure (https://nmisweden.se/), Science for Life Laboratory (SciLifeLab, scilifelab.se) och Euro-BioImaging-ERIC (https://www.eurobioimaging.eu/). CCI erbjuder avancerade avbildningstekniker för forskare inom hela Life Science-området, och även inom kemi, fysik och materialvetenskap. Instrumentparken inkluderar ett flertal laserskanning (konfokal och multifoton) mikroskop, traditionella ljusmikroskop, superresolutions-mikroskop, instrument för MALDI-avbildningsmasspektrometri, liksom svep- (SEM) och transmissionselektromikroskop (TEM). På faciliteten finns också tillgång till laboratorier med utrustning för provberedning inför elektronmikroskopi (EM); både med avseende på provfixering (där fixeringen kan göras både vid rumstemperatur, under kryoförhållanden och med hjälp av mikrovågor), inbäddning och snittning med hjälp av avancerad ultramikrotomteknologi. Det vetenskapligt kunniga teamet på CCI stöttar forskare i design och planering av experiment, och tillhandahåller fördjupad utbildning i hantering av mikroskop, liksom i specifika avbildningstekniker. Utöver det erbjuds stöd i att bearbeta och analysera insamlad data liksom tillhandahållande av nödvändig infrastruktur för behandling och lagring av stora mängder bilddata. CCI:s team har ett stort kontaktnät inom mikroskopiområdet och ett brett samarbete med partners från både akademin och den privata industrin.

CCI söker nu en motiverad och erfaren forskningsinfrastrukturspecialist inom EM och dess olika användningsområden inom Life Science; mer specifikt inom tekniken correlative array tomography (CAT). Befattningen inkluderar deltagande i forskningsprojekt genom ultrastrukturell analys av en mängd olika typer av biologiska prover, vilka inkluderar jästceller, bakterier, insekts- och mammalieceller, men även modellorganismer som flugor, nematoder, fiskar och gnagare. De huvudsakliga arbetsuppgifterna kommer att omfatta provberedning (kemisk och kryofixering, inbäddning, seriell snittning), avbildning (TEM och SEM, seriell TEM, SEM- och TEM-tomografi), användande av avancerade molekylära lokaliseringstekniker (immuno-EM) och CAT; men även träning av användare, liksom underhåll och drift av instrument.

 

Arbetsuppgifter 
Som forskningsinfrastrukturspecialist kommer du arbeta inom CCI och i direkt samarbete med SciLifeLab-plattformen Cellular and Molecular Imaging. Du kommer att assistera forskare genom att tillhandahålla högklassig expertis inom elektronmikroskopisk avbildning genom hela arbetsflödet; från konsultation och experimentdesign, till provhantering, bildtagning, analys och tolkning av erhållen data. Du kommer att arbeta med många olika forskares avbildningsprojekt, men även med att utbilda facilitetens användare i hur de själva använder de rätta EM-teknikerna inom olika forskningsområden (så som cellbiologi, immunologi, parasitologi, cancerbiologi, neurobiologi, biomaterial och klinisk forskning). Arbetet kommer att inkludera användandet av en rad olika tekniker för provberedning, avbildning och analys, både för EM och ljusmikroskopi, ofta kombinerade i korrelativa och multimodala arbetsflöden, inkluderande helcells-/helvävnadsbearbetning (kemiskt eller med kryoteknik) samt snittning av plastinbäddat material eller kryosnittning. Du kommer också vara involverad i projekt för utveckling av tekniker och metoder, där vetenskapliga forskningsfrågor ställer krav på innovativ avbildningsteknik för att kunna möta användarnas behov. Du kommer även vara delaktig i utbildning av användare och doktorander. Som medarbetare är du också med och bidrar till att facilitetens verksamhet i stort fungerar.

 

För övrig information och för att söka anställningen se den fullständiga annonsen på www.gu.se. 

Universitetet arbetar aktivt för en arbetsmiljö med jämställda förhållanden och sätter värde på de kvalitéer mångfald tillför verksamheten.

Universitetet tillämpar individuell lönesättning.

Enligt Riksarkivets föreskrifter är universitetet skyldigt att förvara ansökningshandlingar i två år efter tillsättningsbeslutet. Om du som sökande till en anställning särskilt begär tillbaka dina handlingar återsänds de när de två åren har förflutit, i annat fall kommer de att gallras ut.

Till bemannings- och rekryteringsföretag och till dig som är försäljare: Göteborgs universitet anlitar upphandlad annonsbyrå i samband med rekrytering av personal. Vi undanber oss vänligen men bestämt direktkontakt med bemannings- och rekryteringsföretag samt försäljare av jobbannonser. Visa mindre

We are now recruiting a eConsent Implementation Lead, to join Digital Health R&D.

Digital Health R&D's ambition is to transform healthcare, powered by digital, science and partnerships, to deliver the healthcare outcomes and experience that patients care about the most. Now we are further accelerating our transformation efforts to ensure we demonstrate the best in new technology and leading-edge capabilities to keep us at the forefront of future drug development.

Digital Health R&D is reimagining how we work to position AstraZeneca as an industry leader, making the development & delivery of new medicines easier. We're doing this by harnessing the latest innovations enabled by digital, data & analytics and working with our people to design and build the technology and working practices.

AstraZeneca's Digital Health R&D Patient Health & Innovation organisation develops digital solutions to support our development and commercial drug portfolios. These digital solutions (e.g. Unify) encompass connected monitoring devices and sensors coupled with medical device software to:

* Improve clinical development, through optimising data collection and improving communications between AZ, HCP and patients
* Provide enriched data sets to support regulatory submissions, and differentiated labelling
* Optimise real world medication use by patients and deliver digital interventions to improve clinical outcomes

As part of the Digital Health R&D the team will develop and execute AZ's R&D Digital strategy. The program has already delivered the first versions of bespoke digital solutions for clinical trials globally, built on a standardized set of modules to enable identification and recruitment of patients, ongoing engagement and retention, support to sites and collection of data directly from patients.

The eConsent Implementation Lead is accountable for the processes and procedural documents that meet customer needs and enable optimal delivery of eConsent in clinical studies in a compliant and efficient way.

You will be accountable for the feasibility methodology and execution, assessment process and best practices.as well as for coordinating activities and plans relating to eConsent, with cross functional entities, Digital Health product teams, vendors and enabling functions during setup, conduct and close out.

* Work cross functionally with DH Project Delivery Directors, CPTs, Global & Local Study Teams, Supply Teams, as well as with preferred Suppliers to deliver the smooth implementation of eConsent on each study
* Responsibility to support study eConsent implementation assessments and make recommendations on implementation strategy and adoption based on CSP complexity, DPS components, site feasibility, Regulatory landscape, IRB/IEC submissions and AZ experience
* Supporting Global Study Teams with planning, set up and operational implementation of eConsent including multimedia and device components in adherence to AZ processes and standards and serving as point of escalation through maintenance until study closure
* Contributes to the development of organizational eConsent strategy and responsible for the implementation; performance assessment, metrics management, review of learnings and development and implementation of corrective actions where needed
* Contributes as Operational eConsent SME on the IC Transformation programme; ensures cross-TA operational feasibility and scalability relating to centralization of eConsent processes, technology and services
* Ensure that local (regulatory) requirements associated with the consent and eConsent are incorporated in operational delivery plans - To enable successful implementation at scale.
* Ensure risks, issues and opportunities at the operational level are transparent and actively managed.
* Develop standardized implementation plans, training needs, best practice, and Roll-out plans
* Coordinate Implementation with DH Implementation lead and SIL.

Essential

* Bachelor's Degree in an appropriate discipline or equivalent experience
* Experience within a pharmaceutical or clinical background
* High level of business process knowledge
* Demonstrated project management skills and proven skills to deliver to time, cost and quality in large scale complex projects
* Proven leadership skills promoting motivation and empowerment of others in order to accomplish individual, team and organisational objectives
* Experience in working successfully and collaboratively with external partners delivering mutual benefit
* Ability to identify opportunities, lead and foster cross-functional collaboration, and to work across boundaries
* Demonstrated excellent written and verbal communication and influencing skills, negotiation, presentation, knowledge transfer (mentoring), collaboration, problem solving, conflict management and interpersonal skills
* Knowledge and experience in working in a highly regulated environment
* Experience in GxP system validation
* Experience in GMP and GDP regulatory framework processes

Desirable

* Thrives in a fast-paced work environment, comfortable with complexity and uncertainty at times, lots of humor, dedication to deliver outcomes and motivated by the opportunity to rethink our approach to healthcare.
* Comfort and skills operating in a heavily matrixed organizations with excellent skills and intuition to manage the needs of various partners.
* Ability to rapidly grasp concepts and excellent ability to handle complexity by simplifying it and providing clear directions to the team
* Ability to manage and influence strategically and persuade tactfully, to acquire desired outcomes while maintaining effective, positive, organizational relationships
* Comprehensive understanding of dynamics affecting the pharmaceutical industry and needs for transformation
* Ability to work globally including international travel

So, what's next? Are you already imagining yourself in this position? Good, because we can't wait to hear from you! Welcome with your application. Visa mindre

Göteborgs universitet möter samhällets utmaningar med mångsidig kunskap. 56 000 studenter och 6 600 medarbetare gör universitetet till en stor och inspirerande arbetsplats. Stark forskning och attraktiva utbildningar lockar forskare och studenter från hela världen. Med ny kunskap och nya perspektiv bidrar Göteborgs universitet till en bättre framtid.Vid Institutionen för neurovetenskap och fysiologi vid Sahlgrenska akademin bedrivs omfattande forskning och undervisning över stora kunskapsområden - från molekyl till människa. Verksamheten utgörs av fem sektioner; farmakologi, fysiologi, hälsa och rehabilitering, klinisk neurovetenskap samt psykiatri och neurokemi.

Institutionen för neurovetenskap och fysiologi, söker nu en forskare, med placering vid Sektionen för psykiatri och neurokemi och Wallenbergcentrum för molekylär och translationell medicin.

Sektionen för psykiatri och neurokemi erbjuder världsledande translationell forskning som spänner över cell- och djurmodeller till kliniska studier och omfattande epidemiologiska studier. Här bedrivs framgångsrik forskning inom bland annat bipolär sjukdom, beroendemedicin, åldrande, neurokemi och rättspsykiatri.

Wallenbergcentrum för molekylär och translationell medicin är ett nybildat centrum vid Göteborgs universitet som stödjer molekylär och translationell medicin och är en satsning för att stärka life science i Västsverige. I kombination med det nyöppnade Bild- och Interventionscentrum vid Sahlgrenska sjukhus kommer det att erbjudas utmärkta resurser för avancerade forskningsprojekt inom medicinsk bildgivning.

Arbetsuppgifter

Forskaren kommer att arbeta med projekt som fokuserar på metoder för ligandspecifik PET- samt MRT-databehandling, extraktion och kvantifiering av patologisk information från bilddata. Dessa data kommer att studeras i relation till kliniska resultat, genetisk information, andra bildgivande modaliteter och vätskebaserade biomarkörer.

Mycket goda möjligheter att arbeta med befintliga PET och andra fenotypdata från storskaliga observationsstudier av åldrande och neurodegenerativ sjukdom, samt från pågående dedikerade studier i laboratoriet som använder nya PET-tekniker i valda patientpopulationer kommer att finnas.

Forskaren förväntas utveckla egna forskningsprojekt och aktivt engagera sig i att skriva och publicera vetenskapliga artiklar, presentera forskningen vid internationella konferenser och att ansöka om externa forskningsbidrag.

Kvalifikationer

För att kvalificera sig som forskare bör den sökande ha en doktorsexamen i ett relevant ämne relaterat till projektet som t.ex. biokemi, farmaceutisk biovetenskap, neurovetenskap, analytisk kemi, biofysik.

En grundlig förståelse för neuroimaging, och i synnerhet PET-dataanalys, även modellering av PET-ligandkinetik, en stark bakgrund i statistik och erfarenhet av kliniska forskningsstudier som kombinerar multimodal bildbehandling, fluidbiomarkör, klinisk och/eller genetisk bedömning är ett krav.

Ytterligare krav är kunskaper i engelska på vetenskaplig nivå och dokumenterad stark vetenskaplig skriv- och presentationsförmåga. Erfarenhet av kodning i t ex MATLAB, R och Python är ett plus. Stor vikt kommer att läggas vid personliga egenskaper och lämplighet. Vi lägger stor vikt vid personlig lämplighet. 

Anställning

Anställningen är en tidsbegränsad anställning i 6 månader, 25% av heltid, med placering tills vidare vid Institutionen för neurovetenskap och fysiologi. Tillträde: snarast eller enligt överenskommelse. 

Kontaktuppgifter för anställningen

Har du frågor om anställningen är du välkommen att kontakta universitetslektor Michael Schöll, tfn: +46 705 727 471, e-post: [email protected]

Ansvarig chef är professor/sektionschef Henrik Zetterberg, tfn: +46 31 343 01 42, e-post: [email protected] 

Ansökningshandlingar skickas inte till kontaktpersonerna.

Fackliga organisationer

Fackliga företrädare vid Göteborgs universitet hittar du här: https://www.gu.se/om-universitetet/jobba-hos-oss/hjalp-for-sokande

Ansökan

Du söker anställningen via Göteborgs universitets rekryteringsportal genom att registrera din ansökan elektroniskt via hemsidan: https://www.gu.se/om-universitetet/jobba-hos-oss/lediga-anstallningar 

Du som sökande ansvarar för att ansökan är komplett i enlighet med annonsen och att den är universitetet tillhanda senast sista ansökningsdag.

Intyg om doktorsexamen bifogas med ansökan.

Ansökan ska vara inkommen senast: 2023-05-15

Universitetet arbetar aktivt för en arbetsmiljö med jämställda förhållanden och sätter värde på de kvalitéer mångfald tillför verksamheten.

Universitetet tillämpar individuell lönesättning.

Enligt Riksarkivets föreskrifter är universitetet skyldigt att förvara ansökningshandlingar i två år efter tillsättningsbeslutet. Om du som sökande till en anställning särskilt begär tillbaka dina handlingar återsänds de när de två åren har förflutit, i annat fall kommer de att gallras ut.

Till bemannings- och rekryteringsföretag och till dig som är försäljare: Göteborgs universitet anlitar upphandlad annonsbyrå i samband med rekrytering av personal. Vi undanber oss vänligen men bestämt direktkontakt med bemannings- och rekryteringsföretag samt försäljare av jobbannonser. Visa mindre

Göteborgs universitet möter samhällets utmaningar med mångsidig kunskap. 56 000 studenter och 6 600 medarbetare gör universitetet till en stor och inspirerande arbetsplats. Stark forskning och attraktiva utbildningar lockar forskare och studenter från hela världen. Med ny kunskap och nya perspektiv bidrar Göteborgs universitet till en bättre framtid.Core Facilities är en öppen universitetsgemensam forskningsinfrastruktur för forskning inom Life Science. Vi finns på Sahlgrenska akademin, Göteborgs universitet, och erbjuder tillgång till några av Sveriges mest avancerade tekniker och analysverktyg för forskning inom t.ex. medicin, biomedicin och kliniska studier. Alla våra enheter har stark nationell och internationell profil och vi är del av bland annat SciLifeLab.  Enheterna vid Core Facilities är utrustade med avancerade instrument och specialiserade experter med hög kompetens. Utöver högklassigt forskningsstöd erbjuder vi också teoretisk utbildning och praktiska kurser. Vår infrastruktur är öppen för alla forskare – både vid Göteborgs universitet och vid andra lärosäten och privat industri i Sverige och internationellt. 

Centre for Cellular Imaging (CCI) vid Core Facilities är en av de ledande akademiska mikroskopiinfrastrukturerna i Sverige och tillhandahåller kompetens och tillgång till avancerad mikroskopi både för forskarsamhället lokalt och för forskare vid andra svenska universitet och utomlands. CCI är en del av National Microscopy Infrastructure sedan 2016, en nod i Euro-Bioimaging-ERIC-konsortiet samt medlem i SciLifeLab Cryo-EM-nätverket. 

CCI erbjuder avancerade ljus- och elektronmikroskopitekniker för de olika life science-områdena, men även inom kemi, fysik och materialvetenskap. I utrustningen ingår flera laserskanningsmikroskop (konfokal och multifoton) samt mikroskop för lasermikrodissektion, superupplösning och high-content screening, så väl som ett GEMINI450 skanningselektronmikroskop och ett Talos 120C transmissionselektronmikroskop utrustat med en Ceta-detektor (3D tomografi) och med möjlighet att göra kryo-elektronmikroskopi (kryo-EM) fokuserat på single-particle screening. 

Provberedningsutrustningen för Cryo-EM inkluderar en plunge freezer, glow discharge-utrustning, sputter coater samt ett high pressure freezing-system. Medarbetarna på CCI hjälper forskare inom experimentell design och planering av mikroskopiexperiment och ger fördjupad utbildning i mikroskopihantering, provberedning och specifika avbildningstekniker. Dessutom tillhandahålls stöd vid bildbehandling, framställning av 3D-bilder samt analys av data. 

CCI söker nu en expert inom kryo-elektronmikroskopi och strukturbiologi med stor erfarenhet av single-particle reconstruktion med hög upplösning, inklusive provoptimering, beredning och utvärdering av griddar, datainsamling, användandet av modern mjukvara för selektion och klassificering av partiklar, ”map generation”, modellbyggande och strukturvalidering. Du kommer att bli en integrerad del av CCI-teamet och bidra med kunskap och expertis inom strukturbiologi och kryo-EM för att komplettera vår nuvarande kompetens inom transmissions- och skanningselektronmikroskopi vid rumstemperatur och avancerad ljusmikroskopi. Arbetsuppgifterna kommer att involvera både rutinmetoder och utveckling av nya metoder inom ”single-particle” kryo-EM och att tillämpa dem på ett brett spektrum av forskningsprojekt, dagligt underhåll och drift av instrumenten, provberedning och databearbetning/dataanalys. Verksamheten kan också innefatta att stödja andra EM-applikationer, såsom standardberedning av biologiska prov för TEM och SEM.

 

Arbetsuppgifter 
Du kommer att arbeta inom den avancerade nationella mikroskopifaciliteten Center for Cellular Imaging med: 1) innovativa strukturbiologitekniker, med focus på kryo-EM som en metod för att bestämma strukturen hos nya proteiner som är svåra att beatämma via andra strukturbiologiska tekniker; och 2) utförandet och optimering av olika arbetsflöden för kryo-EM grid-provberedning för single-particle och kryo-EM screening; 3) drift och underhåll av elektronmikroskop samt utrustning för kryo-EM-provberedning, inklusive högtrycksfrysning och plunge-frysning; 4) rådgivning om utformningen av avbildningsexperiment för att optimera slutresultat och forskningsverksamheten; 5) förbereda inför datainsamling genom att utföra preliminär utvärdering av bilddatakvalitet, ladda prover och göra inställningar av mikroskop;  6) delta i genomförandet av nya innovativa kryo-EM-metoder för att möta användarnas behov vid CCI och i samarbete med single-particle Cryo-EM National Facility i Stockholm på SciLifeLab; 7) rådgivning till användare om upprening och analys av såväl enskilda proteiner som proteinkomplex; 8) utföra allmänt labbunderhåll efter behov: upprätthålla laboratorielagret, inventera kemikalier och tillhandahålla allmänt labsupport; samt 9) delta i undervisningen inom forskar- och grundutbildning.

 

För övrig information och för att söka anställningen se den fullständiga annonsen på www.gu.se.

Universitetet arbetar aktivt för en arbetsmiljö med jämställda förhållanden och sätter värde på de kvalitéer mångfald tillför verksamheten.

Universitetet tillämpar individuell lönesättning.

Enligt Riksarkivets föreskrifter är universitetet skyldigt att förvara ansökningshandlingar i två år efter tillsättningsbeslutet. Om du som sökande till en anställning särskilt begär tillbaka dina handlingar återsänds de när de två åren har förflutit, i annat fall kommer de att gallras ut.

Till bemannings- och rekryteringsföretag och till dig som är försäljare: Göteborgs universitet anlitar upphandlad annonsbyrå i samband med rekrytering av personal. Vi undanber oss vänligen men bestämt direktkontakt med bemannings- och rekryteringsföretag samt försäljare av jobbannonser. Visa mindre

Are you a Cheminformatics Specialist with an interest in working closely with chemists and biologists in a hit identification environment? Would you like to make use of your informatics skills to provide expert advice and push the boundaries of science to make a change? If so, join our journey to develop and deliver novel medicines!

As our new Cheminformatics Specialist you will be a part of the Hit Discovery department in Discovery Sciences. The role has covers new technology development and application in the area of hit identification and automated chemistry and has a special focus on supporting our DNA-encoded libraries team in medicinal chemistry. You will be based at AstraZeneca's R&D site in Gothenburg, Sweden or Cambridge, UK.

Discovery Sciences is part of the global BioPharmaceuticals organisation and provides scientific support to early drug discovery across the global discovery portfolio. The Hit Discovery department is responsible for the discovery of novel chemical hits in four principal areas: High-throughput screening, Fragment-Based Lead Generation, DNA-encoded libraries, and Virtual Screening, augmented by automated chemistry and AI/machine learning.

What you'll do:
Apply and adapt cheminformatics software and science in the fields of DNA-encoded libraries, automated chemistry and Virtual Screening to support compound and data handling, reaction informatics, analysis and learning from data. Other key elements in the role as Cheminformatics specialist include the exploitation and adaptation of cheminformatics technology to support the work and the data handling of chemists and biologist in hit discovery and automated chemistry.

You will provide expert advice and interpretation of complex data and devise, champion and develop the scientific area of Cheminformatics that aligns with the Hit Discovery department mission.

Essential in the role:

* PhD in the area of Cheminformatics or Computational Chemistry with several years of experience combined with profound technical skills like computer programming and systems design, or a degree in Computer Sciences with demonstrated additional knowledge and experiences in a relevant area of science, as chemistry, physics, or biology.
* Demonstrated experience with a variety of software tools and technologies (e.g., Java, C++, Python/Ruby/Perl, , or AWS).
* Experience within a research-based scientific computing environment.
* Excellent knowledge of modern computational chemistry/computer science methods and algorithms and its use in drug hunting projects.

You should also be able to work and collaborate in a multidisciplinary research matrix environment, as well as providing scientific insights. A good understanding of how the drug discovery process functions within discovery and how computational methods contribute to and influence projects is a plus.

Why AstraZeneca?
Be part of a dedicated Research & Development team. Fuelled by our commitment to help more patients, strengthen our pipeline and grow our area. Thrive in a place where the brightest and most curious minds seamlessly come together in our inclusive environment.

So, what's next? If this sounds like the job and place for you to make a change - apply today!

We look forward to get to know you better. Please send your application to us no later than 16th April. 2023.

For more information about the position please contact hiring manager Jens Sadowski at +46 31 7762850.

Additional information:
Our Gothenburg site: https://www.astrazeneca.com/our-science/gothenburg.html
Our Cambridge site: https://www.astrazeneca.com/our-company/our-locations/cambridge.html
About BioPharmaceuticals R&D: https://www.astrazeneca.com/r-d.html

This position entitles competitive salary and benefits package on offer. Visa mindre

Are you excited about Precision Medicine? Would you like have an impact on patients' lives and contribute to eliminate cancer as a cause of death? If so then join us!

We're investing like never before in our people, in growth, and in new diagnostic techniques and technologies. There are opportunities at every turn, with a variety and breadth that is uncommon to find and an industry-leading pipeline in oncology. Scientists at AstraZeneca are working every day to turn science fiction into science fact. Our ambition - to develop innovative, targeted medicines for every patient that needs them - and to match those treatments to patients most likely to benefit from them - is now a reality. This approach, known as Precision Medicine, is based on those individual characteristics that make some patients respond to treatment better than others. We use this knowledge to develop diagnostic tests that doctors can use to help prescribe the best treatment for each patient. Indeed, it's now become common practice for patients with cancer to be offered such diagnostic tests before their treatment plan is agreed.

The AstraZeneca Companion Diagnostics Unit within the Precision Medicine and Biosamples function drives scientific leadership through the delivery of innovative companion diagnostics enabling our oncology ambition to transform the lives of patients living with cancer, and ultimately eliminate cancer as a cause of death.

We do this by:

*

Leading the development of diagnostics across AstraZeneca's early and late stage oncology portfolios through close collaborations with our external diagnostic partners.
*

Leading the development and implementation of patient selection strategies to deliver companion diagnostics programs in support of our business priorities.
*

Leading companion diagnostic regulatory interactions to secure companion diagnostic approvals in major markets
*

Collaborate across AstraZeneca with colleagues in multiple Clinical functions plus commercial to help drive market uptake.
*

Developing strategies for early cancer detection, near patient testing and implementing testing options for minimal residual disease and early treatment interventions.
*

Utilising artificial intelligence diagnostic solutions and seeing software as a medical device.
*

Developing specific disease area strategies (e.g. lung cancer, breast cancer or hematological malignancies) and new diagnostic modalities.
*

Collaborating closely with fellow pharma companies on joint assets.

Join this fantastic, collaborative team and be part of our success; we have already delivered over 50 innovative/impactful companion/complementary oncology diagnostic approvals across the major markets of the US, EU, Japan and China since 2014 and we need you to help us take the next steps in patient-centric diagnostic development.

What you'll do
As an Associate Director you'll be a member of the Oncology Companion Diagnostic Unit (CDU). Your objective will be to ensure that innovative companion diagnostic tests are delivered to our oncology drug projects. This will entail developing and implementing the diagnostic strategy agreed by the respective development teams, and planning and leading Precision Medicine activities from a technical, financial, risk, regulatory, IP and partnering perspective. You will work collaboratively with colleagues at all levels in the Precision Medicine function to deliver this expertise to drug project teams. Your role will also involve contributing to the personal development of project team members. Providing expert advice on strategic and innovative Precision Medicine approaches and companion diagnostic developments to development teams, you'll be instrumental in ensuring that we adopt world-class practice in the field.

Essential for the role

*

PhD or equivalent experience in a relevant subject
*

Experience in companion diagnostic tests or segmentation tools in clinical development OR experience of Precision Medicine approaches and diagnostic development
*

Effective communication, stakeholder, influencing skills and programme management
*

Understanding of the functions involved in companion diagnostic development and how they contribute

Desirable

*

Previous experience in similar role in different companies
*

Delivery of clinical testing, diagnostic, regulatory preparation.
*

Scientific expertise in the Precision Medicine field or relevant therapeutic area as evidenced by publications

Locations

Sweden - Gothenburg; Poland - Warsaw, Barcelona, Spain or Mississauga, Canada.

If this sounds like the type of organisation where you would like to grow your career and make a real difference to patients then we would like to hear from you; apply today! Visa mindre

The University of Gothenburg tackles society’s challenges with diverse knowledge. 56 000 students and 6 600 employees make the university a large and inspiring place to work and study. Strong research and attractive study programmes attract scientists and students from around the world. With new knowledge and new perspectives, the University contributes to a better future.The Institute of Biomedicine is involved in both research and education. In both of these areas, we focus on fundamental knowledge of the living cell – what it consists of, how it works, how its function is directed by the genetic material, and how it interacts with various kinds of micro-organisms. Using this knowledge, we try to elucidate the causes of diseases, and find new ways to diagnose and treat them.

The Institute is composed of the following four departments:


• The Department of Infectious Diseases
• The Department of Microbiology and Immunology
• The Department of Medical Biochemistry and Cell Biology
• The Department of Laboratory Medicine

At present, the institute has about 360 employees and approximately 450 million SEK in total assets. 

Subject area 
Mitochondrial DNA replication and transcription

Subject area description 
Mitochondria contain their own genome that codes for several subunits of the respiratory chain. We have developed both in vivo and in vitro techniques to study mitochondrial DNA replication.

Duties 
Mitochondria contain their own genome that codes for several subunits of the respiratory chain. We have developed in vivo and in vitro techniques to study the basic mechanisms of human mitochondrial DNA replication and transcription, and how these processes are regulated.

With this project the candidate will investigate the biochemical mechanisms of proteins involved in mitochondrial genome replication and/or transcription. Our laboratory has identified new proteins involved in these processes, which will be examined both in vivo and in vitro using classic biochemistry, cell biology, and next generation sequencing techniques.

Eligibility 
The eligibility criteria for employing teaching staff are set out in Chapter 4 of the Higher Education Ordinance and in the Appointment Procedure for Teaching Posts at the University of Gothenburg. 

To be eligible for appointment as a postdoc, the applicant is required to have a doctoral degree, a doctoral degree in art or a foreign degree that is deemed to be equivalent to a doctoral degree. This eligibility requirement must be met before the employment decision is made. 

In the first instance, those who have completed their degree no more than three years prior to the end of the application period shall be considered. Those who have completed their degree more than three years prior to the end of the application period may also be considered in the first instance if special grounds exist. Special grounds relate to leave of absence due to illness, parental leave, commissions of trust within union organisations, service within the defence services or other similar circumstances, as well as clinical service or service/assignment relevant to the subject area. 

Assessment criteria 
Regulations for the evaluation of qualifications for academic positions are given in Chapter 4, Section 3 - 4 of the Higher Education Ordinance.

We are looking for a highly motivated individual with a recent PhD and experience of in vitro biochemical characterization of purified recombinant proteins. Knowledge of mitochondrial systems and documented experience with cloning, mutagenesis, gene expression, cell culture, radiolabeled isotopes, and in vitro DNA replication and/or transcription are of merit. The work will involve collaboration both within and outside the group as well as with a biotech company, and so good teamwork and communication skills are important. The candidate is expected to be enthusiastic, capable of planning and executing research independently, and to have a passion and curiosity for science. Fluent written and spoken English is required since we operate in a very international environment.

Employment 
The employment is full time and temporary, two years with the possibility of one year's extension, with placement at the Institute of Biomedicine. First day of employment as agreed.

Selection process 
How to apply: https://www.gu.se/om-universitetet/jobba-hos-oss/hjalp-for-sokande#Så-här-går-rekryteringsprocessen-till 

Contact information 
If you have any questions about the position, please contact Maria Falkenberg, professor. Phone: +46 (0)31 786 3444, e-mail: [email protected]

Unions 
Union representatives at the University of Gothenburg can be found here:?https://www.gu.se/om-universitetet/jobba-hos-oss/hjalp-for-sokande 

Application 

Submit your application via the University of Gothenburg’s recruitment portal by clicking the “Apply” button. It is your responsibility to ensure that the application is complete as per the vacancy notice, and that the University receives it by the final application deadline.  

The application should contain:


• A cover letter giving a brief description of previous research experience, and a motivation to why you are applying
• A CV including a list of publications
• Proof of completed PhD
• Contact details of two references

Applications must be received by: 2023-02-28? 

 

Information for International Applicants 

Choosing a career in a foreign country is a big step. Thus, to give you a general idea of what we and Gothenburg have to offer in terms of benefits and life in general for you and your family/spouse/partner please visit: 

https://www.gu.se/en/about-the-university/welcome-services 
https://www.movetogothenburg.com/ 

The University works actively to achieve a working environment with equal conditions, and values the qualities that diversity brings to its operations.

Salaries are set individually at the University.

In accordance with the National Archives of Sweden’s regulations, the University must archive application documents for two years after the appointment is filled. If you request that your documents are returned, they will be returned to you once the two years have passed. Otherwise, they will be destroyed.

In connection to this recruitment, we have already decided which recruitment channels we should use. We therefore decline further contact with vendors, recruitment and staffing companies. Visa mindre

Göteborgs universitet möter samhällets utmaningar med mångsidig kunskap. 56 000 studenter och 6 600 medarbetare gör universitetet till en stor och inspirerande arbetsplats. Stark forskning och attraktiva utbildningar lockar forskare och studenter från hela världen. Med ny kunskap och nya perspektiv bidrar Göteborgs universitet till en bättre framtid.Vid Institutionen för neurovetenskap och fysiologi vid Sahlgrenska akademin bedrivs omfattande forskning och undervisning över stora kunskapsområden - från molekyl till människa. Verksamheten utgörs av fem sektioner; farmakologi, fysiologi, hälsa och rehabilitering, klinisk neurovetenskap samt psykiatri och neurokemi. Institutionen för neurovetenskap och fysiologi, söker nu en forskare, med placering vid Sektionen för psykiatri och neurokemi.

Vid sektionen för psykiatri och neurokemi vid Institutionen för neurovetenskap och fysiologi vid Sahlgrenska akademin bedrivs neurokemisk forskning med inriktning att identifiera och studera patofysiologi och patologier vid neurodegenerativa sjukdomar. Patologiska kännetecken vid Alzheimers sjukdom inkluderar aggregering av specifika peptider och proteiner i hjärnan. Idag finns tre biomarkörer, som mäts i ryggvätska, som används för att diagnostisera Alzheimers sjukdom men dessa kan endast användas ganska sent i sjukdomsförloppet och de har relativt stort överlapp mellan sjuk och frisk. Således behöver vi nya markörer som speglar olika sjukdomsmekanismer för att kunna ställa en tidig och säker diagnos.

Arbetsuppgifter 
I arbetsuppgifterna ingår att vara delaktig samt leda flera olika projekt och tillsammans med andra forskare etablera och validera nya metoder, tillämpa dessa metoder i kliniska neurokemiska studier och i slutändan skriva vetenskapliga artiklar. Vetenskaplig handledning av studenter och personal ingår också i uppdragen. Analysmetoder inkluderar antikroppsbaserade metoder såsom ELISA, Simoa, men kan också innefatta ytterligare tekniker som analys av PET- och MRI-avbildning.

Kvalifikationer
För att kvalificera sig som forskare bör den sökande ha en doktorsexamen i ett relevant ämne samt innehaft en postdoktortjänst. Den sökande ska ha dokumenterad kunskap om och erfarenhet av forskning om biomarkörer (vätska och bildbehandling) för neurodegenerativa sjukdomar, dataanalys och grundläggande kunskaper i statistik.

Vi söker en positiv och driven forskare med lång erfarenhet av forskning och laboratoriearbete kring biomarkörer för neurodegenerativa sjukdomar. Vid bedömning av de sökandes meriter kommer stor vikt att läggas vid forskningserfarenhet med fokus på metodutveckling och implementering av nya biomarkörer samt dataanalys. Detta bör dokumenteras genom publikationer i internationella peer-reviewade vetenskapliga tidskrifter. God förmåga att självständigt bearbeta data och skriva vetenskapliga publikationer är väsentligt samt att i övrigt vara flexibel och kunna arbeta både i grupp och självständigt. Vid bedömning kommer hänsyn att tas med avseende på personlig förmåga och kvalifikationer. Vi lägger stor vikt vid personlig lämplighet. 

Anställning
Anställningen är en tidsbegränsad anställning i 11 månader, 100% av heltid, med placering tills vidare vid Institutionen för neurovetenskap och fysiologi. Tillträde: snarast eller enligt överenskommelse.  

Kontaktuppgifter för anställningen
Har du frågor om anställningen är du välkommen att kontakta ansvarig chef är professor/sektionschef Henrik Zetterberg, tfn: +46 768 672 647, e-post: [email protected]

Ansökningshandlingar skickas inte till kontaktpersonerna.

Fackliga organisationer
Fackliga företrädare vid Göteborgs universitet hittar du här: https://www.gu.se/om-universitetet/jobba-hos-oss/hjalp-for-sokande

Ansökan
Du söker anställningen via Göteborgs universitets rekryteringsportal genom att registrera din ansökan elektroniskt via hemsidan: https://www.gu.se/om-universitetet/jobba-hos-oss/lediga-anstallningar

Du som sökande ansvarar för att ansökan är komplett i enlighet med annonsen och att den är universitetet tillhanda senast sista ansökningsdag.

Intyg om doktorsexamen bifogas med ansökan.

Ansökan ska vara inkommen senast: 2023-02-13

Universitetet arbetar aktivt för en arbetsmiljö med jämställda förhållanden och sätter värde på de kvalitéer mångfald tillför verksamheten.

Universitetet tillämpar individuell lönesättning.

Enligt Riksarkivets föreskrifter är universitetet skyldigt att förvara ansökningshandlingar i två år efter tillsättningsbeslutet. Om du som sökande till en anställning särskilt begär tillbaka dina handlingar återsänds de när de två åren har förflutit, i annat fall kommer de att gallras ut.

Till bemannings- och rekryteringsföretag och till dig som är försäljare: Göteborgs universitet anlitar upphandlad annonsbyrå i samband med rekrytering av personal. Vi undanber oss vänligen men bestämt direktkontakt med bemannings- och rekryteringsföretag samt försäljare av jobbannonser. Visa mindre

Göteborgs universitet möter samhällets utmaningar med mångsidig kunskap. 56 000 studenter och 6 600 medarbetare gör universitetet till en stor och inspirerande arbetsplats. Stark forskning och attraktiva utbildningar lockar forskare och studenter från hela världen. Med ny kunskap och nya perspektiv bidrar Göteborgs universitet till en bättre framtid.

 

Vid institutionen för kemi och molekylärbiologi bedrivs forskning och forskarutbildning inom ett brett område som sträcker sig hela vägen från atom- och molekylskala via celler till hela organismer. Mycket av de fenomen som studeras har en inverkan på vår naturliga miljö och levande system. Vi deltar i utbildning på grundläggande nivå inom programmen för kemi, molekylärbiologi, läkemedelskemi, biologi, marina vetenskaper och apotekarprogrammet. 

Björn Burmanns gruppering använder toppmodern NMR-spektroskopi, i kombination med andra strukturbiologiska metoder samt biofysikalisk karaktärisering, för att studera stora molekylkomplex i syfte att förstå grundläggande cellulära funktioner på atomnivå, t.ex proteinkvalitetskontroll och deras effekt på felveckningd- och aggregeringsbenägn a proteiner som ligger till grund för flera olika sjukdomar. Resultat från tidigare studier av melekylära chaperoner och funktionella mekanismer för proteases på atomnivå har publicerats i tidskrifter (Burmann et al. NSMB 2013, Thoma et al, NSMB 2015, Burmann et al., Nature 2020, Mas et al. Sci. Adv.  2020, Sulskis et al., Sci. Adv. 2021). Mer information om vår forskning finns på: (www.wcmtm.gu.se/research-groups/burmann).Ämne: Strukturell biologi, biofysik och biokemi. Ämnesbeskrivning: Strukturell karakterisering och biofysik analys av proteaser mekanismer.

Arbetsuppgifter 
Projektet syftar till att, med hjälp av avancerad NMR-spektroskopi, främja vår molekylära förståelse av funktion och reglering hos homooligomera serinproteaser på atomnivå. Om dessa viktiga maskiner inte regleras ordentligt leder det till av felveckade proteiner kan ge grunden för olika sjukdomar.Specifikt kommer studenterna att studera (1) de molekylära mekanismerna som regler och aktiveratbakteriell HtrA2 (2) hur hur proteaserna känner igen och därefter klyver sina felveckade proteinsubstrat, och (3) hur proteaset samverkar med adaptorproteiner för att justera sin funktion. Research Engineer kommer att arbetamed ett brett spektrum av vetenskapliga uppgifter och forskningsfrågor som kräver ett genuint intresse för, och kunskap om, allt från grundläggande biokemi till avancerade strukturella biologiska metoder. Forskningsarbetet kommer även att innefatta metoder inom mikrobiologi, molekylärbiologi, bioinformatik samt biokemi. Vi söker en kollega, som är mycket motiverad, vetenskapligt oberoende och kreativ och kan bidra till en lagmiljö.

Kvalifikationer 
Vi söker dig med minst en masterexamen i till exempel inom molekylärbiologi, biokemi, biofysik, strukturell biologi eller relaterade områden förväntas. Tidigare arbete med relaterade proteinsystem kommer att anses gynnsamt.  Bedömningsgrunder vid anställning som lärare finns angivna i 4 kap 3 - 4 § högskoleförordningen samt Göteborgs universitets egen anställningsordning. Den framgångsrika kandidaten ska ha en stark bakgrund inom biokemi, biofysik och/eller NMR-spektroskopi. Tidigare arbete med homooligomera serinproteaser, t.ex. uttryck och rening och/eller funktionell karakterisering för strukturstudier, anses vara en fördel. Att ha detaljerad erfarenhet av följande obligatoriska tekniker:


• Kunskaper av rekombinant proteinuttryck och rening av relevante proteiner, till exempel HtrA2.
• Expertkunskap i lösning NMR-spektroskopi av proteiner (t.ex. uppdrag, proteindynamik, dataanalys)


• Expertkunskap i provberedning (isotopmärkning, metylmärkning)


• Detaljerad kunskap i ytterligare biofysiskateknik (ITC, BLI, SEC-MALLS, EM, X-Ray)
• Dokumenterad kunskap inom automatiserad databehandling och analys

Dessutom krävs ett genuint intresse för struktur och dynamik eller proteinfunktion. Samförfattarskap i tidskrifter med hög impact-faktor, som Nature, Science eller Science Advances  anses gynnsamma.

Anställning 
Anställningen är en tidsbegränsad anställning på 6 månader vid institutionen för Kemi och Molekylärbiologi.

 

Kontaktuppgifter för anställningen 
Har du frågor om anställningen är du välkommen att kontakta Björn Burmann, Associate Professor, +46(0)31 786 3923 [email protected]

Fackliga?organisationer 
Fackliga företrädare vid Göteborgs universitet hittar du här:?https://www.gu.se/om-universitetet/jobba-hos-oss/hjalp-for-sokande 

Ansökan 
För att söka en anställning vid Göteborgs universitet måste du registrera ett konto i vårt rekryteringssystem. Du söker anställningen via Göteborgs universitets rekryteringsportal genom att klicka på knappen "Ansök". Du som sökande ansvarar för att ansökan är komplett i enlighet med annonsen och att den är universitetet tillhanda senast sista ansökningsdag . 

Ansökan ska innehålla:
Ett personligt brev med motivering till varför du söker tjänsten
CV som inkluderar vetenskapliga publikationer
Kopia på examensbevis
Två personliga referenser (namn, telefonnr, relation)

Ansökan ska vara inkommen senast:2022-12-08


Universitetet arbetar aktivt för en arbetsmiljö med jämställda förhållanden och sätter värde på de kvalitéer mångfald tillför verksamheten.

Universitetet tillämpar individuell lönesättning.

Enligt Riksarkivets föreskrifter är universitetet skyldigt att förvara ansökningshandlingar i två år efter tillsättningsbeslutet. Om du som sökande till en anställning särskilt begär tillbaka dina handlingar återsänds de när de två åren har förflutit, i annat fall kommer de att gallras ut.

Till bemannings- och rekryteringsföretag och till dig som är försäljare: Göteborgs universitet anlitar upphandlad annonsbyrå i samband med rekrytering av personal. Vi undanber oss vänligen men bestämt direktkontakt med bemannings- och rekryteringsföretag samt försäljare av jobbannonser. Visa mindre

Job description
Background:
Melt&Marble;’s mission is to enable the transition towards a more sustainable food system. We do this by using precision fermentation to develop the best and tastiest fats for plant-based foods. By engineering microbial metabolism, we can brew animal-free fats that mimic the structures and sensory properties of animal fats. The result: tastier foods, for people and the planet.
We are expanding our team and looking to attract enthusiastic & mission-driven people to join us on our journey.


Position summary:
We are looking for a motivated scientist with solid experience in lipid chemistry to work on application development for Melt&Marble;’s fats. You will be our in-house expert on fat/oil functionality and part of our new food science division, working together with 2-3 colleagues. As one of the first employees in the food science division, you will have a strong influence on the product/application development direction at Melt&Marble;, and will work cross-functionally with the other teams in the company to define further product iterations and help guide commercial strategy.
Our ideal candidate should have a strong track record in lipid chemistry, strong organizational skills, and a passion for using science & technology to solve tough challenges. The candidate should also be comfortable working in the dynamic environment of a start-up company, dealing with changes and constant iterations, troubleshooting challenging projects, and meeting tight deadlines.
Occasionally, some activities may require working outside of standard working hours. The position might require travel within Sweden and abroad.


Activities:
Assisting in defining target compositions and performance metrics for fats & oils for priority applications (e.g. meat & dairy analogues)
Defining evaluation methodologies and criteria for assessment of different fats & oils
Evaluating the physical, chemical, and organoleptic properties of different fats and oils based on above criteria
Testing fats and oils in different alternative protein matrices
Developing new formulations of Melt&Marble; fats & oils in priority applications
Developing criteria and tests for lipid quality analysis/control
Preparing spec sheets for Melt&Marble; fats & oils
Liaising with external stakeholders (e.g. service providers, customers)
Maintaining detailed records of experiments and results in Melt&Marble;’s data management system
Preparing technical reports, SOPs, and presentations
Assisting in coordinating regulatory approval of Melt&Marble; ingredients



Job requirements
Required qualifications:
Msc/PhD in Biochemistry, Food Chemistry/Science/Technology, Chemistry, or another relevant subject
>3 years of experience studying the structure and functional properties of fats & oils, preferably in an industrial setting
Solid familiarity with standard methods for lipid studies (e.g. AOCS)
Deep understanding of lipid chemistry, including thermal behaviour, oxidation/degradation, crystallization behaviour, and behaviour in food matrices (interactions with proteins & other lipids, water, hydrocoloids, etc.)
Experience with analytical methods and instruments to assess lipid quality (e.g. PV, AV, IV, etc.) and composition (e.g. GC-MS/FID, HPLC, lipidomics, etc.)
Experience with methods to assess lipid thermal behaviour (e.g. DSC, NMR)
Excellent organizational and time management skills
Excellent written and oral communication skills in English



Bonus points:
Experience in analysis of the rheological properties of fats
Experience working with lipids in meat and dairy analogues
Experience in designing in conducting sensory tests for fats & oils
Experience in developing intellectual property
Experience/knowledge of regulatory approval for novel food ingredients
Swedish/EU citizen or permanent resident



We offer:
An innovative, interdisciplinary, and fun research environment where you can advance in your career
Unique opportunity to participate in innovative projects that solve real world problems
Work in the lovely city of Gothenburg- Sweden’s second-largest city. Gothenburg is a seaside city that offers a great combination of city life and beautiful surrounding nature
Flexible work hours, competitive remuneration, generous vacation package, benefits



Application procedure:
Applications should contain the following:
Cover letter- tell us about what excites you about this space and why you think that you’re a great fit for Melt&Marble; (300 words max)
CV
Publication list (if relevant)
References: contact information of 2 current/former supervisors and 1 current/former colleague



Please submit all application materials in English


Please apply here - https://meltandmarble.recruitee.com/o/research-scientist-fats-and-oils


Application deadline: Rolling. We encourage interested candidates to apply early as applications might be evaluated as they are received.
If you have any questions about the position, feel free to contact us at [email protected]. Visa mindre

Are you excited about Precision Medicine? Would you like have an impact on patients' lives and contribute to eliminate cancer as a cause of death? If so then join us!

We're investing like never before in our people, in growth, and in new diagnostic techniques and technologies. There are opportunities at every turn, with a variety and breadth that is uncommon to find and an industry-leading pipeline in oncology. Scientists at AstraZeneca are working every day to turn science fiction into science fact. Our ambition - to develop innovative, targeted medicines for every patient that needs them - and to match those treatments to patients most likely to benefit from them - is now a reality. This approach, known as Precision Medicine, is based on those individual characteristics that make some patients respond to treatment better than others. We use this knowledge to develop diagnostic tests that doctors can use to help prescribe the best treatment for each patient. Indeed, it's now become common practice for patients with cancer to be offered such diagnostic tests before their treatment plan is agreed.

The AstraZeneca Companion Diagnostics Unit within the Precision Medicine and Biosamples function drives scientific leadership through the delivery of innovative companion diagnostics enabling our oncology ambition to transform the lives of patients living with cancer, and ultimately eliminate cancer as a cause of death.

We do this by:

*

Leading the development of diagnostics across AstraZeneca's early and late stage oncology portfolios through close collaborations with our external diagnostic partners.
*

Leading the development and implementation of patient selection strategies to deliver companion diagnostics programs in support of our business priorities.
*

Leading companion diagnostic regulatory interactions to secure companion diagnostic approvals in major markets
*

Collaborate across AstraZeneca with colleagues in multiple Clinical functions plus commercial to help drive market uptake.
*

Developing strategies for early cancer detection, near patient testing and implementing testing options for minimal residual disease and early treatment interventions.
*

Utilising artificial intelligence diagnostic solutions and seeing software as a medical device.
*

Developing specific disease area strategies (e.g. lung cancer, breast cancer or hematological malignancies) and new diagnostic modalities.
*

Collaborating closely with fellow pharma companies on joint assets.

Join this fantastic, collaborative team and be part of our success; we have already delivered over 50 innovative/impactful companion/complementary oncology diagnostic approvals across the major markets of the US, EU, Japan and China since 2014 and we need you to help us take the next steps in patient-centric diagnostic development.

If this sounds like the type of organisation where you would like to grow your career and make a real difference to patients then we would like to hear from you.

Locations: Gothenburg Sweden, Warsaw Poland, Barcelona Spain, or Mississauga, Canada.

What you'll do:
As a Director, you'll be a member of the Oncology Companion Diagnostic Unit (CDU). Your objective will be to ensure that innovative companion diagnostic tests or equivalent segmentation tools are delivered to our oncology drug projects. Drawing on world-class expertise and personal experience in companion diagnostic development you will ensure the adoption of Precision Medicine approaches within the AstraZeneca business. You will also provide leadership and support to a pool of fellow diagnostic experts to ensure delivery of a diagnostic strategy.

This will entail developing and implementing the diagnostic strategy agreed by the respective development teams, and planning and leading Precision Medicine activities from a technical, financial, risk, regulatory, IP and partnering perspective. You will work collaboratively with colleagues at all levels in the Precision Medicine function to deliver this expertise to drug project teams.

Your role will also involve contributing to the personal development of project team members. Providing expert advice on strategic and innovative Precision Medicine approaches and companion diagnostic developments to development teams, you'll be instrumental in ensuring that we adopt world-class practice in the field.

Essential:

*

PhD or equivalent experience in a relevant subject.
*

Experience of companion diagnostic tests or patient biomarker/segmentation tools in clinical development.
*

Experience of Precision Medicine approaches and diagnostic development within the relevant therapeutic area.
*

Effective communication, stakeholder, influencing skills and programme management.

*

Significant understanding of the functions involved in companion diagnostic development and how they contribute to achieving successful diagnostic submissions and approvals

Desirable :

*

Significant previous experience in a similar role in different companies.
*

Delivery of companion diagnostics, regulatory interactions and commercialisation.
*

High quality scientific expertise in the field of Precision Medicine or relevant therapeutic area as evidenced by publications.

If this sounds like the type of organisation where you would like to grow your career and make a real difference to patients then we would like to hear from you; apply today! Visa mindre

Job description
Associate Director, Compliance Human Biological Samples

Reason for the role:
Human Biological Samples (HBS) are fundamental to medical research in the discovery, development and implementation of new treatments and diagnostics. HBS are ethically sensitive materials and the collection, handling, and access to HBS are subject to strict regulations, principles, and ethical guidelines.

Responsibilities
Day-to-Day Duties


Lead the Identification and establishment of effective HBS compliance procedures across R&D.
Manage HBS processes to ensure standards are adhered to and compliance requirements are consistently applied.
Ensuring senior stakeholders are aware of changing legislation that impacts them.
Support the business with compliant use of HBS through expert advice and decision making.
Ensure risks arising from HBS due diligence activities are identified and recorded.
Maintain the documentation/SOPs associated with HBS due diligence activities.


Qualifications
Required Skills/ Experience/ Education/ Qualifications


Degree level education
Experience in pharmaceuticals, a healthcare related industry or academia/hospital environment related to HBS
Excellent analytical, written, and oral communications skills
High ethical standards, willingness to challenge inappropriate proposals/actions of senior leaders
Strong collaborative, partnering, and interpersonal skills

Desirable Skills/ Experience/ Education/ Qualifications


Direct experience of working with HBS
Experienced of working with multiple stakeholders
Previous experience as a process owner and process improvement
Experience in collection and use of HBS as part of ongoing clinical trials
Expert in relevant global regulations relating to HBS


Application
Deadline: 2022-10-22, selection and interviews will be ongoing. 
The position may be filled before the last day of application, therefore, apply as soon as possible. 

For more information: 
Please contact Katan Ali, 
[email protected]

About the company
About randstad life sciences 
Randstad Life Sciences is specialized in competencies within Life Science. As a consultant with us, you get a competitive salary, benefits, and collective agreements. Your consultant manager is always there for you and ensures that you get varying and developing assignments at different companies, within different industries. At Randstad Life Sciences, your personal development is in focus, and you are offered a large network and many activities.

With more than 600 000 employees in 38 countries, Randstad is the global leader in the HR services industry and offers staffing, consulting and recruitment solutions in all areas of expertise. We also offer interim management, executive search and outplacement services. We have a broad network of clients and candidates, which means we convey hundreds of jobs within different industries all over Sweden. Our ambition is to be the best employer in the market.

By combining our passion for people with the power of today’s technology, we help people and organizations to reach their true potential. We call it Human Forward. Visa mindre

Job description
We at Randstad Life Sciences are currently looking for scientists for upcoming
consulting assignments in the pharmaceutical industry in Gothenburg. This upcoming position offers the opportunity to work in a dynamic and enthusiastic environment while providing an important service to drug development projects. The work is highly collaborative with the team sharing responsibility for overall performance. The role focuses on supporting drug discovery projects within the R&D department in Gothenburg by maintaining high quality handling and storage of HBS and supporting projects with requested samples in a timely manner.

Responsibilities
Biobank scientists are responsible for the storage and timely supply  of human biological samples (HBS) for research projects. HBS are obtained from clinical trials or academic collaborations, for example, stored in local biobanks, and distributed to projects. The group primarily supports the Sweden region, but also collaborates with other biobank groups within the Biospecimen Division worldwide to ensure efficient support within our company and partner organizations.
 
The Biobank Group works collaboratively to provide support within agreed service levels, with a focus on our customers. We strive hard to understand the needs of our customers and add value through our services. As the value and use of biobank samples becomes more prominent, we actively seek ways to improve our processes or leverage new technologies to build a state-of-the-art facility.
 
The role is focused on supporting drug discovery projects within R&D Gothenburg by maintaining a high quality handling and storage of HBS and support projects with requested samples in a timely manner.

As a Biobank Research Scientist you will be expected to:
Work as part of the team rotating between the following typical tasks
Receive and register incoming HBS
Process requests for HBS to customers
Manage customer orders using specialized informatics systems as well as databases
Responding to customer queries via mail or telephone
Partner with Biobank groups globally as well as internal and external customers and stakeholders
Act upon day-to-day issues that occur whilst processing HBS samples to ensure continuous improvement
Identify initiatives to improve efficiency or quality.

The group has a strong emphasis on continuous improvement which takes the form of individual and group projects within the team, the department and across Biobank groups.

Qualifications
Minimum experience: Ideally, you have a degree in a bioscience or chemistry field and have previous experience in laboratory work with biological samples. Previous knowledge and experience in biobanking is a plus.  Experience of working with various IT solutions, including extensive knowledge of Excel, LIMS systems and database usage, is also a clear advantage. The biobank team is a highly collaborative group working to tight delivery schedules so the ability to be comfortable working at a fast pace with a goal orientated and team focussed attitude is essential. Excellent communication skills with a proactive and service minded approach is key. Preferred experience/requirements: Experience of automated liquid handling and/or tissue sectioning is advantageous. Good analytical and problem-solving skills involving large and complex datasets Key Attributes. 


Ability to plan, perform and evaluate experiments to investigate improvement possibilities in a process
Knowledge of the drug discovery process
Interest in logistics and developing processes through customer interactions and technology awareness
Drive and enthusiasm to solve the root cause of problems and not only overcome the presenting problem
Thrive on working in a committed team and gain satisfaction from the overall performance of the group


Application
For more information: 
Please contact Katan Ali 
[email protected]

Randstad Life Sciences is specialized in competencies within Life Science. As a consultant with us, you get a competitive salary, benefits, and collective agreements. Your consultant manager is always there for you and ensures that you get varying and developing assignments at different companies, within different industries. At Randstad Life Sciences, your personal development is in focus, and you are offered a large network and many activities.

About the company
Randstad Life Sciences is specialized in competencies within Life Science. As a consultant with us, you get a competitive salary, benefits, and collective agreements. Your consultant manager is always there for you and ensures that you get varying and developing assignments at different companies, within different industries. At Randstad Life Sciences, your personal development is in focus, and you are offered a large network and many activities.

With more than 600 000 employees in 38 countries, Randstad is the global leader in the HR services industry and offers staffing, consulting and recruitment solutions in all areas of expertise. We also offer interim management, executive search and outplacement services. We have a broad network of clients and candidates, which means we convey hundreds of jobs within different industries all over Sweden. Our ambition is to be the best employer in the market.

By combining our passion for people with the power of today’s technology, we help people and organizations to reach their true potential. We call it Human Forward. Visa mindre

Are you a passionate and experienced scientist, eager to join a company in the forefront of sample management technologies? Would you like to contribute to the continuous improvement of life changing projects? Perfect, we have a new challenge for you!

We are looking for a motivated and engaged team member to work as a Senior Scientist in our Compound Management team at our vibrant R&D site at AstraZeneca in Gothenburg, Sweden.

As a Senior Scientist in Compound Management you will be responsible for the storage and timely supply of chemical compounds to AstraZeneca's drug discovery projects. Highly automated liquid handling systems will be employed to supply molecules to AstraZeneca scientists and partner organisations. You will be a part of the Discovery Sciences organisation, operating within a first-class scientific environment to support drug discovery across each of AstraZeneca's Therapeutic Areas.

Thrive in a place where the brightest and most curious minds seamlessly come together in our inclusive environment.

What you will do:
In this position, you will get the opportunity to work in a dynamic and enthusiastic environment, whilst delivering critical support to drug discovery projects. You are focused on supporting projects by providing compounds in the requested format - assay ready plates, serially diluted mother plates, formulations and solids. You will be involved in all phases of the projects and support a broad range of chemical modalities. Bringing in new capabilities and build new processes are also core activities, performed in collaboration with cross functional drug discovery projects.

You are expected to act upon day-to-day issues that occur whilst processing samples and ensure business continuity and you will run Compound Management development projects to ensure continuous improvement within the local team and the global department.

Furthermore, you will work with the following typical tasks:

* Designing, performing and interpreting experiments independently to investigate process improvements and evaluate new technologies.
* Rapidly addressing customer queries with regards to Compound Management orders, software, processes and capabilities.
* Achieving personal scientific visibility through project contributions, internal presentations and publications.

We work collaboratively within our Compound Management team, to provide support within agreed service levels and with a strong quality and customer focus. We strive hard to understand what fits customer needs and how to add value through our experience and capabilities. To maintain this position, we actively seek ways to improve our process and exploit new technologies.

Essential in the role:
Compound Management is a highly collaborative group, working to tight delivery schedules - so the ability to be comfortable working at a fast, goal-oriented pace, with a team focused attitude is essential to be successful in the role. We also believe you have:

* A BSc/MSc in Chemistry or biotechnology/Chemical engineering, with relevant experience.
* Expertise with analytical balances and automated liquid handlers.
* Excellent problem-solving skills and ability to identify and implement improvement activities.
* Some experience in workflow automation and IT (/Python/Java coding).
* A track record in the performance of a range of practical skills, including non-routine complex tasks, to a high level.

We also believe that our new colleague share our passion for science, technology and innovation. Is a strong team player with a high work ethic that enjoys working in a collaborative setting. You have good social and communication skills with a proactive delivery - and costumer focused approach. Previous experience of working in a compound management role and operating integrated automation equipment and scheduling software is beneficial.

Why AstraZeneca?
Here we are committed to making a difference. We have built our business around our passion for science. Now we are fusing data and technology with the latest scientific innovations to achieve the next wave of breakthroughs.

So, what's next? If you're passionate about the possibilities of science to make a difference, welcome to join us!

We look forward to get to know you and invite you to submit your application as soon as possible, but no later than the 23rd October, 2022.

For more information about the position please contact Karin Kaspersson, Director - Compound Synthesis and Management, at Karin.Kaspersson(at)astrazeneca.com.

Additional information:
Our Gothenburg site: https://www.astrazeneca.com/our-science/gothenburg.html
Life in Gothenburg: https://www.movetogothenburg.com/
Make a move to Global Gothenburg: https://www.youtube.com/watch?v=c-Iqbb4aw38 Visa mindre

The University of Gothenburg tackles society’s challenges with diverse knowledge. 56 000 students and 6 600 employees make the university a large and inspiring place to work and study. Strong research and attractive study programmes attract scientists and students from around the world. With new knowledge and new perspectives, the University contributes to a better future.

 

Subject area 
Structure and function of GPCR signaling complexes.

Subject area description 
G protein-coupled receptors (GPCRs) are key transmembrane proteins that serve to transduce external stimuli to signals across the membrane and they constitute about 30-40% of all therapeutic drug targets. GPCRs are inherently allosteric and interact via distinct domains with both endogenous and synthetic compounds, proteins, metabolites, hormones and small molecules. Methodological breakthroughs have accelerated structure determination of GPCRs, however our understanding of the molecular basis of signaling complexes remain elusive.  We will characterize these complexes using structural, biophysical and pharmacological methods.

Duties 
The successful candidates will work on the structure and function of select GPCR signaling complexes using a combination of structural, biochemical and pharmacological approaches. The candidates will be encouraged and expected to conduct their research independently and to plan and execute research tasks in a timely manner. The candidates are also expected to travel for data collection purposes and to participate in collaborations with other research groups (either within Sweden or abroad). Additionally, the candidates may also be asked to assist in supervision of Master’s or doctoral students.

Eligibility 
The eligibility criteria for employing teaching staff are set out in Chapter 4 of the Higher Education Ordinance and in the Appointment Procedure for Teaching Posts at the University of Gothenburg. 

To be eligible for appointment as a postdoc, the applicant is required to have a doctoral degree, a doctoral degree in art or a foreign degree that is deemed to be equivalent to a doctoral degree. This eligibility requirement must be met before the employment decision is made. 

In the first instance, those who have completed their degree no more than three years prior to the end of the application period shall be considered. Those who have completed their degree more than three years prior to the end of the application period may also be considered in the first instance if special grounds exist. Special grounds relate to leave of absence due to illness, parental leave, commissions of trust within union organisations, service within the defence services or other similar circumstances, as well as clinical service or service/assignment relevant to the subject area.  

Assessment criteria 
We are looking for candidates with an interest in signaling, structural biology or pharmacology. The applicants must have a PhD in a relevant area of research such as medicine/biology/chemistry/pharmacology or related fields (for example structural biology, biochemistry or biophysics). The successful candidates should have extensive experience in cell cultivation (preferably eukaryotic cells), signaling, interaction studies as well as protein purification. Great emphasis will be placed on the candidate’s personal suitability for the position and interest in the subject area as well as their long-term research goals. The work involves close collaborations with other researchers and thus demands flexibility and a willingness to travel for data collection purposes.  Excellent communication skills (spoken and written) in English are a prerequisite for the position.

Regulations for the evaluation of qualifications for academic positions are given in Chapter 4, Section 3 - 4 of the Higher Education Ordinance.

Employment 
The employment is full time and temporary, two years with the possibility of one year's extension, with placement at the Institute of Biomedicine. First day of employment as agreed.

Contact information 
If you have any questions about the position, please contact Linda Johansson; email: [email protected]; telephone: +46(0)766183244.


Unions 
Union representatives at the University of Gothenburg can be found here:?https://www.gu.se/om-universitetet/jobba-hos-oss/hjalp-for-sokande 

Application 

Submit your application via the University of Gothenburg’s recruitment portal by clicking the “Apply” button. It is your responsibility to ensure that the application is complete as per the vacancy notice, and that the University receives it by the final application deadline.  

The application should contain:

- A cover letter giving a brief description of previous research experience, and a motivation to why you are applying

- A CV including a list of publications

- Proof of completed PhD

- Contact details of two references

Applications must be received by: 2022-09-19

 

Information for International Applicants 

Choosing a career in a foreign country is a big step. Thus, to give you a general idea of what we and Gothenburg have to offer in terms of benefits and life in general for you and your family/spouse/partner please visit: 

https://www.gu.se/en/about-the-university/welcome-services 
https://www.movetogothenburg.com/ 


The University works actively to achieve a working environment with equal conditions, and values the qualities that diversity brings to its operations.

Salaries are set individually at the University.

In accordance with the National Archives of Sweden’s regulations, the University must archive application documents for two years after the appointment is filled. If you request that your documents are returned, they will be returned to you once the two years have passed. Otherwise, they will be destroyed.

In connection to this recruitment, we have already decided which recruitment channels we should use. We therefore decline further contact with vendors, recruitment and staffing companies. Visa mindre

Are you truly passionate about the magic that happens in the lab and could see yourself applying your protein science knowledge in a successful pharmaceutical company? Would you like to join a team of highly skilled scientists where both your professional and personal skills are valued? If yes, this might be the spot for you!

We have an exciting opportunity for a Senior Scientist with protein science skills to join us, working within a dynamic scientific environment to support drug discovery. The Discovery Biology department within Discovery Sciences is responsible for the generation of novel reagents and assays to support projects in all phases of the drug discovery pipeline. We focus on scientific advances in small molecules, oligonucleotides and other new technologies and drug discovery platforms across our different core areas.

Thrive in a place where the brightest and most curious minds seamlessly come together in our inclusive environment.

What you will do:
You will be responsible for producing and characterizing recombinant proteins including enzymes, secreted proteins, transcription factors and proteins with less characterized functions. These proteins are used to enable drug discovery projects. Since this position is lab based, we expect that you get a lot of energy from being in the lab and have a true real passion for practical duties. We also want you to contribute to our specific field developments in the team.

In the daily work, we rely on you to deliver expertise in recombinant protein production and characterization, of different target class proteins. As well as work in partnership with global colleagues to ensure the delivery of high-quality protein reagents to projects and contribute with novel ideas and using discernment and knowledge where appropriate to influence project progression.

You will regularly work across functional boundaries to define what is needed for discovery projects and lead protein work to deliver to that. With your knowledge in a range of procedures relating to construct design, protein expression and purification of a diverse set of target proteins, you will plan and conduct laboratory projects and experimental strategies, develop methods and technologies, generate, interpret and report scientific data autonomously.

Essential in the role:

* PhD in biochemistry, biology or pharmacology or other a related field, or an MSc degree with significant relevant experience from pharmaceutical or biotechnology industry.
* Expertise and proven knowledge of a wide range of methods and technologies applied to the expression, purification and characterization of a diverse set of target proteins. E.g. construct design and protein engineering, bacterial expression, liquid chromatography, SDS-PAGE, mass spectrometry and biophysical techniques.

To be successful in this role you also need to enjoy collaboration and team work - and have the skill to interact and communicate efficiently across interfaces of global functions and fields in a multi-cultural settings. This goes hand in hand with your problem-solving and critical thinking skills, and strong delivery focus.

Desirable in the role:

* Target-class specific knowledge related to e.g. intrinsically disordered proteins, transcription factors or signaling proteins.
* Experience with high-throughput methods for protein purification at medium scale.
* Expertise in machine learning to predict protein expression.

Why AstraZeneca in Gothenburg?
Our Gothenburg site is one of AstraZeneca's three strategic R&D centres. Here, you'll feel a global atmosphere in a multinational environment. Collaboration comes in all forms - across teams, functions, countries and even companies. We nurture this collaboration and openness, by creating a site that has space for meetings, socialising and relaxation - where spontaneous moments can spark innovation.

So, what happens next? If this sounds like the job and place for you - apply today!

We look forward to get to know you better. Please send in your application as soon as possible, but no later than 25th September, 2022.

For more information about the position please contact hiring manager Lovisa Holmberg Schiavone at lovisa.holmberg.schiavone(at)astrazeneca.com.

Additional information:
Our AstraZeneca Gothenburg site: https://www.astrazeneca.com/our-science/gothenburg.html
Make a move to Gothenburg: https://www.astrazeneca.se/om-oss/verksamheten-i-sverige/goteborg/relocate-to-gothenburg.html
About BioPharmaceuticals R&D: https://www.astrazeneca.com/r-d.html Visa mindre

Are you excited about Precision Medicine? Would you like have an impact on patients' lives and contribute to eliminate cancer as a cause of death? If so then join us!

We're investing like never before in our people, in growth, and in new diagnostic techniques and technologies. There are opportunities at every turn, with a variety and breadth that is uncommon to find and an industry-leading pipeline in oncology. Scientists at AstraZeneca are working every day to turn science fiction into science fact. Our ambition - to develop innovative, targeted medicines for every patient that needs them - and to match those treatments to patients most likely to benefit from them - is now a reality. This approach, known as Precision Medicine, is based on those individual characteristics that make some patients respond to treatment better than others. We use this knowledge to develop diagnostic tests that doctors can use to help prescribe the best treatment for each patient. Indeed, it's now become common practice for patients with cancer to be offered such diagnostic tests before their treatment plan is agreed.

The AstraZeneca Companion Diagnostics Unit within the Precision Medicine and Biosamples function drives scientific leadership through the delivery of innovative companion diagnostics enabling our oncology ambition to transform the lives of patients living with cancer, and ultimately eliminate cancer as a cause of death.

We do this by:

*

Leading the development of diagnostics across AstraZeneca's early and late stage oncology portfolios through close collaborations with our external diagnostic partners.
*

Leading the development and implementation of patient selection strategies to deliver companion diagnostics programs in support of our business priorities.
*

Leading companion diagnostic regulatory interactions to secure companion diagnostic approvals in major markets
*

Collaborate across AstraZeneca with colleagues in multiple Clinical functions plus commercial to help drive market uptake.
*

Developing strategies for early cancer detection, near patient testing and implementing testing options for minimal residual disease and early treatment interventions.
*

Utilising artificial intelligence diagnostic solutions and seeing software as a medical device.
*

Developing specific disease area strategies (e.g. lung cancer, breast cancer or hematological malignancies) and new diagnostic modalities.
*

Collaborating closely with fellow pharma companies on joint assets.

Join this fantastic, collaborative team and be part of our success; we have already delivered over 50 innovative/impactful companion/complementary oncology diagnostic approvals across the major markets of the US, EU, Japan and China since 2014 and we need you to help us take the next steps in patient-centric diagnostic development.

If this sounds like the type of organisation where you would like to grow your career and make a real difference to patients then we would like to hear from you.

We are currently looking for a Director.

What you will be doing
As a Director, you'll be a member of the Oncology Companion Diagnostic Unit (CDU). Your objective will be to ensure that innovative companion diagnostic tests or equivalent segmentation tools are delivered to our oncology drug projects. Drawing on world-class expertise and personal experience in companion diagnostic development you will ensure the adoption of Precision Medicine approaches within the AstraZeneca business. You will also provide leadership and support to a pool of fellow diagnostic experts to ensure delivery of a diagnostic strategy.

This will entail developing and implementing the diagnostic strategy agreed by the respective development teams, and planning and leading Precision Medicine activities from a technical, financial, risk, regulatory, IP and partnering perspective. You will work collaboratively with colleagues at all levels in the Precision Medicine function to deliver this expertise to drug project teams.

Your role will also involve contributing to the personal development of project team members. Providing expert advice on strategic and innovative Precision Medicine approaches and companion diagnostic developments to development teams, you'll be instrumental in ensuring that we adopt world-class practice in the field.

Essential:

*

PhD or equivalent experience in a relevant subject.
*

Experience of companion diagnostic tests or patient biomarker/segmentation tools in clinical development.
*

Experience of Precision Medicine approaches and diagnostic development within the relevant therapeutic area.
*

Effective communication, stakeholder, influencing skills and programme management.

*

Significant understanding of the functions involved in companion diagnostic development and how they contribute to achieving successful diagnostic submissions and approvals

Desirable :

*

Significant previous experience in a similar role in different companies.
*

Delivery of companion diagnostics, regulatory interactions and commercialisation.
*

High quality scientific expertise in the field of Precision Medicine or relevant therapeutic area as evidenced by publications.

If this sounds like the type of organisation where you would like to grow your career and make a real difference to patients then we would like to hear from you; apply today! Visa mindre

AstraZeneca is a global, science-led, patient-focused biopharmaceutical company that focuses on the discovery, development and commercialisation of prescription medicines for some of the world's most serious diseases. But we're more than one of the world's leading pharmaceutical companies. At AstraZeneca, we are pioneering new frontiers by identifying and treating patients earlier, working towards the aim of eliminating cancer as a cause of death.

Come and join our AZ team where you will play a pivotal role in this exciting period of development!

Human Biological Samples (HBS) are fundamental to medical research in the discovery, development and implementation of new treatments and diagnostics. They are ethically critical materials and underpin the delivery of every clinical trial.

What you'll do
As the Third Party Lab (TPL) Contract Information Manager you are responsible for Third Party Lab (TPL) human biological sample (HBS) operational contracting activities within a project. You are responsible for setting up and coordinating all TPLs contracted by AZ Translational Medicine and Translational Science for analysis using HBS for exploratory testing.

*

Ensure AZ contracted analysis using HBS is high quality, compliant and delivers the scientific and operational needs of the project
*

TPL Scope of Work (SOW) development, operational management of the contracted work, PO tracking, data transfers and risk and issue management
*

Build and maintain relevant documentation e.g. vendor communication and escalation plan, vendor monitoring and QC plan, including eTMF upload.
*

Contribute to study specific documentation such as Clinical Study Protocol, central lab SOW, Sample Lifecycle plan, eCRF, data transfer specification or agreement and risk log.
*

Ongoing operational monitoring of TPL during lifecycle of contract through to closure, including contract amendments
*

Operational tracking of centrally located HBS via Global Code and other central tools
*

Regular reporting of operational contracted activities to key partners
*

Oversight of TPL data transfers and query resolution
*

Work closely with Quality Assurance (QA) and Procurement as they handle QA Operational Due Diligence and Procurement activities related to TPLs.
*

Can be assigned to specific tasks across Biosamples as required
*

Chip in to the development of new processes and deployment of automation technologies where required
*

Developing, maintaining and applying ongoing knowledge and awareness in trends, best practices and innovation in laboratory information management and country regulations
*

Ensure compliance of the assigned activities with GCP, HGR and other country specific regulations

Minimum Qualifications:

*

Experience with leading and negotiating Research and Development specific contracts.
*

Degree (or relevant equivalent qualification) in relevant area, or relevant equivalent industry experience.
*

Proficient in English as the AstraZeneca working language
*

A clear demonstration of behaviours of
*

Truth seeking rather than success seeking
*

Agile responsiveness to scientific data
*

Accepting of peer review
*

Problem solver
*

Demonstration of the AZ values
*

Customer management
*

Project management

Desired Qualifications:

*

Clinical Laboratory scientific experience
*

Experience in more than one company or country
*

Confirmed experience in contributing to operational deployment of clinical laboratory testing
*

Validated experience in oversight of external partners, especially clinical laboratory service providers

At AstraZeneca, we 're dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and ignite your entrepreneurial spirit. There's no better place to make a difference to medicine, patients and society. An inclusive culture that champions diversity and collaboration, and always committed to lifelong learning, growth and development. We're on an exciting journey to pioneer the future of healthcare

So, what's next:
Are you already envisioning yourself joining our team? Good, because we can't wait to hear from you! Please apply as soon as possible but no later than 4 July, 2022.



Where can I find out more?

Follow AstraZeneca on LinkedIn https://www.linkedin.com/company/1603/

Follow AstraZeneca on Facebook https://www.facebook.com/astrazenecacareers/

Follow AstraZeneca on Instagram https://www.instagram.com/astrazeneca_careers/?hl=en Visa mindre

The University of Gothenburg tackles society’s challenges with diverse knowledge. 56 000 students and 6 600 employees make the university a large and inspiring place to work and study. Strong research and attractive study programmes attract scientists and students from around the world. With new knowledge and new perspectives, the University contributes to a better future.

The Institute of Biomedicine is involved in both research and education. In both of these areas, we focus on fundamental knowledge of the living cell – what it consists of, how it works, how its function is directed by the genetic material, and how it interacts with various kinds of micro-organisms. Using this knowledge, we try to elucidate the causes of diseases, and find new ways to diagnose and treat them.

The Institute is composed of the following four departments:


• The Department of Infectious Diseases
• The Department of Microbiology and Immunology
• The Department of Medical Biochemistry and Cell Biology
• The Department of Laboratory Medicine

At present, the institute has about 360 employees and approximately 450 million SEK in total assets

 

Subject area 
Mitochondrial DNA replication and transcription

 
Subject area description 
Mitochondria contain their own genome that codes for several subunits of the respiratory chain. We have developed in vivo and in vitro techniques to study the basic mechanisms of human mitochondrial DNA replication and transcription, and how these processes are regulated.

 

Duties 
With this project the candidate will investigate the biochemical mechanisms of proteins involved in mitochondrial genome replication and/or transcription. Our laboratory has identified new proteins involved in these processes, which will be examined both in vivo and in vitro using classic biochemistry, cell biology, and next generation sequencing techniques.

 

Eligibility 
The eligibility criteria for employing teaching staff are set out in Chapter 4 of the Higher Education Ordinance and in the Appointment Procedure for Teaching Posts at the University of Gothenburg. 

 

To be eligible for appointment as a postdoc, the applicant is required to have a doctoral degree, a doctoral degree in art or a foreign degree that is deemed to be equivalent to a doctoral degree. This eligibility requirement must be met before the employment decision is made. 

In the first instance, those who have completed their degree no more than three years prior to the end of the application period shall be considered. Those who have completed their degree more than three years prior to the end of the application period may also be considered in the first instance if special grounds exist. Special grounds relate to leave of absence due to illness, parental leave, commissions of trust within union organisations, service within the defence services or other similar circumstances, as well as clinical service or service/assignment relevant to the subject area.  

 

 

Assessment criteria 
We are looking for a highly motivated individual with a recent PhD and experience of in vitro biochemical characterization of purified recombinant proteins. Knowledge of mitochondrial systems and documented experience with cloning, mutagenesis, gene expression, cell culture, radiolabeled isotopes, and in vitro DNA replication and/or transcription are of merit. The work will involve collaboration both within and outside the group, and so good teamwork and communication skills are important. The candidate is expected to be enthusiastic, capable of planning and executing research independently, and to have a passion and curiosity for science. Fluent written and spoken English is required since we operate in a very international environment.

Regulations for the evaluation of qualifications for academic positions are given in Chapter 4, Section 3 - 4 of the Higher Education Ordinance.

 

Employment 
The employment is full time and temporary, two years with the possibility of one year's extension, with placement at the Institute of Biomedicine. First day of employment as agreed.

 

Contact information 
If you have any questions about the position, please contact Maria Falkenberg, Professor, +46 (0)317863444, [email protected]

For more information about our research, please visit our webpage: www.falkenberglab.org

 

Unions 
Union representatives at the University of Gothenburg can be found here:?https://www.gu.se/om-universitetet/jobba-hos-oss/hjalp-for-sokande 

 

Application 

Submit your application via the University of Gothenburg’s recruitment portal by clicking the “Apply” button. It is your responsibility to ensure that the application is complete as per the vacancy notice, and that the University receives it by the final application deadline.  

The application should contain:

- A cover letter giving a brief description of previous research experience, and a motivation to why you are applying

- A detailed CV including a list of publications

- Proof of completed PhD

- Contact details of two references.

 

Applications must be received by: 2022-07-19

 

? 

Information for International Applicants 

Choosing a career in a foreign country is a big step. Thus, to give you a general idea of what we and Gothenburg have to offer in terms of benefits and life in general for you and your family/spouse/partner please visit: 

https://www.gu.se/en/about-the-university/welcome-services 
https://www.movetogothenburg.com/ 


The University works actively to achieve a working environment with equal conditions, and values the qualities that diversity brings to its operations.

Salaries are set individually at the University.

In accordance with the National Archives of Sweden’s regulations, the University must archive application documents for two years after the appointment is filled. If you request that your documents are returned, they will be returned to you once the two years have passed. Otherwise, they will be destroyed.

In connection to this recruitment, we have already decided which recruitment channels we should use. We therefore decline further contact with vendors, recruitment and staffing companies. Visa mindre

Företagsbeskrivning
AFRY är ett ledande europeiskt företag med global räckvidd inom teknik, design och rådgivning. Vi accelererar omställningen mot ett hållbart samhälle.
Vi är 16 000 hängivna experter inom infrastruktur, industri, energi och digitalisering, som skapar hållbara lösningar för kommande generationer.
Making Future


Jobbeskrivning
Bioreaktorkunnig ingenjör till vår Future Food-satsning med placering i Göteborg.
Är du den vi söker?
AFRYs mission är att accelerera omställningen till ett hållbart samhälle. Det gör vi bland annat genom att arbeta tillsammans med våra kunder och driva förändring för att omvandla industriella processer globalt. Vi bidrar till att öka produktiviteten och effektiviteten samt att positionera banbrytande teknik och kompetens i ett brett spann av branscher.
Inom livsmedelsektorn råder en spännande tid med många nya bolag och utveckling av nya slags livsmedel. Med vetskapen om det stora klimatavtryck som kommer från vår livsmedelsproduktion, och den brådska det är att få till nya lösningar för en mer klimatvänlig diet, satsar vi inom AFRY stort för att på bästa sätt hjälpa till med utveckling och uppskalning av framtidens mat. Mat som producerats på ett smart och effektivt sätt. Mat som både smakar bra och som följer de krav som ställs, samtidigt som den är bra för planeten.
På Food&Pharma; har vi lång erfarenhet av att designa, installera och driftsätta såväl livsmedel- som GMP-klassade anläggningar. Projekten varierar både i storlek och komplexitet.
Vi har ett stort fokus på att transformera dessa branscher för att säkra en hållbar framtid och satsar därför extra inom segmentet Future Food. Vi känner väl till utmaningarna med att skala upp en produktion och den potential som digitalisering ger för en mer hållbar produktion. Vi jobbar nära våra kunder och hjälper många mindre bolag i tidiga skeden.
Användandet av fermentering och bioreaktorer är en viktig del inom framtidens matproduktion och vi söker nu rätt person för att stärka detta område där mat och bioteknik går ihop.
Drivs du av att hitta nya lösningar, jobba i framkant och vara med där det händer? Brinner du för att bidra till positiv förändring inom livsmedelsproduktion med fokus på framtidens mat?
Har du dessutom erfarenhet och kunskap inom fermentering och cellodlingsteknologi i bioreaktorsystem, då vill vi gärna prata mer med dig!

För att trivas i rollen hos oss tror vi att du tycker om att arbeta i projektform och har en god förmåga att kommunicera. Du är teknikintresserad och engagerad som person. Utöver din tekniska kompetens värdesätter du de personliga egenskaper som krävs i projekt; att vara lyhörd, tydlig, och motiverad att leverera det bästa för såväl projektet som för kunden.
Därtill är det för denna roll viktigt att du behärskar både svenska och engelska i tal och skrift.


Kravspecifikation
Bakgrund:
· Utbildning inom bioteknik med minst 5 års arbetslivserfarenhet.
· Erfarenhet av, och kunskap om, fermentering inom food/feed eller läkemedel.
· Erfarenhet av design och kravställning av bioreaktorsystem och nedströmsprocesser.
Meriterande:
· Erfarenhet av uppskalning från lab till pilotskala, och/eller från pilotskala till fullskalig produktion.
· Upphandlat och driftsatt bioreaktorsystem och nedströmsprocesser.
· GMP- kännedom.
Känns detta intressant? Tveka inte, hör av dig och häng med på en spännande resa! Vi ser fram emot att få lära känna dig.


Ytterligare information
Vi söker dig som vill vara en del av AFRYs framgångssaga. Brinner du för teknisk utveckling? Gillar du att samarbeta för att hitta den bästa lösningen? Då kan vi erbjuda dig karriärmöjligheter på en modern arbetsplats med utmanande arbetsuppgifter och spännande projekt världen över. Hos oss är du med och utvecklar innovativa och hållbara lösningar för framtidens samhälle inom infrastruktur, energi och industri.
På AFRY tycker vi att det är viktigt med en balans mellan arbete och fritid. Vår fantastiska Club AFRY, som drivs av engagerade medarbetare, ordnar evenemang utanför jobbet för att just du ska trivas. Det finns något för alla – från opera till skidresa och allt däremellan.
AFRY som arbetsgivare erbjuder en trygg anställning med kollektivavtal och attraktiva förmåner. Vi vill att våra anställda har en vardag att trivas i. Visste du att AFRY är rankat som en av Sveriges mest populära arbetsgivare bland ingenjörer? Vi vill gärna visa dig varför.
För frågor om tjänsten, hör gärna av dig!
Vi intervjuar löpande, så skicka gärna in din ansökan redan nu. Vi kan komma att tillsätta tjänsten innan annonstiden har gått ut.
Startdatum: Enligt överenskommelse
Placeringsort: Göteborg
Omfattning: Heltid, 100 %

För frågor kopplat till din ansökan, kontakta Anna Svensson, [email protected].
Rekryterande chef Ann Winzell, [email protected].
AFRY is committed to creating an inclusive & diverse environment and we are actively looking for qualified candidates irrespective of gender, gender identity, sexual orientation, ethnicity, religion, disability, or age. You will be part of a global and diverse company where our differences are our strengths. Join us to accelerate the transition towards a sustainable society.
AFRY is committed to creating an inclusive & diverse environment and we are actively looking for qualified candidates irrespective of gender, gender identity, sexual orientation, ethnicity, religion, disability, or age. You will be part of a global and diverse company where our differences are our strengths. Join us to accelerate the transition towards a sustainable society. Visa mindre

Göteborgs universitet möter samhällets utmaningar med mångsidig kunskap. 56 000 studenter och 6 600 medarbetare gör universitetet till en stor och inspirerande arbetsplats. Stark forskning och attraktiva utbildningar lockar forskare och studenter från hela världen. Med ny kunskap och nya perspektiv bidrar Göteborgs universitet till en bättre framtid.

Institutionen för kemi och molekylärbiologi bedriver högkvalitativ forskning och utbildning inom kemiska vetenskaper och molekylära livsvetenskaper. Vår forskning och utbildning fokuserar på en djup förståelse av kemiska och biologiska processer i celler och i miljön. Institutionen är en internationell miljö med tvärvetenskapliga samarbeten inom både forskning och utbildning, och bidrar starkt till Göteborgs universitets topprankning inom life science. Institutionen samverkar med olika samhällsaktörer som skolor, näringsliv och myndigheter. Institutionen för kemi och molekylärbiologi har runt 200 anställda. Vi finns i centrala lokaler både på Campus Johanneberg och på Campus Medicinareberget i Göteborg.

 Gruppen S. Westenhoff studerar de strukturella förändringarna av fytokromers fotosensorproteiner med hans ERC-anslag MOLSTRUCDYN. Fytokromer är ljusavkännande proteiner som övervakar nivån, intensiteten, varaktigheten och färgen på miljöljus. De kontrollerar många ljusberoende processer i växter, svampar och bakterier. Fytokromer är lovande mål inom det växande området för optogenetik för att möjliggöra exakt ljuskontroll av olika interna cellulära processer. I detta projektarbete kommer du att utforska NMR-spektroskopi av fytokromproteiner i nära samarbete med NMR-centret och professor V Orekhov.

Arbetsuppgifter 
Den framgångsrika kandidaten kommer att vara involverad och tillhandahålla/dela sin expertis inom NMR assignment (backbone and methyl) av stora proteinsystem i tillämpning på det monomera (509 rester) fotosensoriska modulfragmentet (PAS-GAF-PHY) av DrBphP vid dess flera funktionella tillstånd. Särskilt fokus kommer att ligga på att använda CCPN-programvara. Du kommer att interagera med de andra medlemmarna i ERC-projektet om tidsupplöst struktur, och bidra med dina resultat till bättre förståelse av proteinet och som förberedelse för tidsupplösta strukturella experiment genom kristallografi och röntgenspridning. 

Kvalifikationer 

• När du påbörjar anställningen måste du ha MS-examen i biofysik, strukturbiologi eller liknande ämne.
• Utbildning på MS-nivå i NMR-spektroskopi
• Praktisk erfarenhet av att använda CCPN-mjukvara för tilldelning av stora proteinsystem, samt programvara för NMR spektrabearbetning och grafisk presentation av proteinstrukturer
• Flytande engelska

Meriterande är: erfarenhet av AlphaFold och python-programmering

Anställning 
Anställningen är tidsbegränsad anställning på heltid,100 % under sex månader med placering vid Institutionen för kemi och molekylärbiologi

Kontaktuppgifter för anställningen 
Har du frågor om anställningen är du välkommen att kontakta professor: Vladislav Orekhov tel: +46 31 786 38 86, e-post: [email protected]

Fackliga?organisationer 
Fackliga företrädare vid Göteborgs universitet hittar du här:?https://www.gu.se/om-universitetet/jobba-hos-oss/hjalp-for-sokande  

Ansökan 
För att söka en anställning vid Göteborgs universitet måste du registrera ett konto i vårt rekryteringssystem. Du söker anställningen via Göteborgs universitets rekryteringsportal genom att klicka på knappen "Ansök". Du som sökande ansvarar för att ansökan är komplett i enlighet med annonsen och att den är universitetet tillhanda senast sista ansökningsdag 2022-06-09 

Komplett ansökan innehåller i PDF-format:


• Personligt brev
• CV
• Bevis om examen på avancerad nivå eller fullgjorda kurser, se behörighetskrav ovan
• Två referenser (namn, mailadress, telefonnummer, relation)

Ansökan ska vara inkommen senast: 2022-06-09 


Universitetet arbetar aktivt för en arbetsmiljö med jämställda förhållanden och sätter värde på de kvalitéer mångfald tillför verksamheten.

Universitetet tillämpar individuell lönesättning.

Enligt Riksarkivets föreskrifter är universitetet skyldigt att förvara ansökningshandlingar i två år efter tillsättningsbeslutet. Om du som sökande till en anställning särskilt begär tillbaka dina handlingar återsänds de när de två åren har förflutit, i annat fall kommer de att gallras ut.

Till bemannings- och rekryteringsföretag och till dig som är försäljare: Göteborgs universitet anlitar upphandlad annonsbyrå i samband med rekrytering av personal. Vi undanber oss vänligen men bestämt direktkontakt med bemannings- och rekryteringsföretag samt försäljare av jobbannonser. Visa mindre

At AstraZeneca we turn ideas into life changing medicines and strive to continuously meet the unmet needs of patients worldwide. Working here means being entrepreneurial, thinking big, and working together to make the impossible a reality. If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you're our kind of person.

We continually push the boundaries of science to deliver medicines that treat diseases across our main therapy areas. Through our integration with Alexion, this now includes expanding the limits of scientific research to better understand rare diseases and to discover new life-changing treatments for them.

Pharmaceutical Sciences is a department within AstraZeneca Biopharmaceutical R&D. The Pharmaceutical Sciences' mission is to transform molecules into investigational medicines, meeting the unmet needs of future patients. Advanced Drug Delivery is a department in Pharmaceutical Sciences. Our portfolio of projects spans traditional small molecules, proteins, oligonucleotides to RNA based therapeutics across AstraZeneca's therapy areas and our mission is to transform diverse modalities into investigational medicines.

We are now looking for a senior drug delivery scientist with strong expertise in the formulation and analytical sciences to work on delivering new modalities for gene therapy. The position is based at our vibrant R&D site in Gothenburg, Sweden.



What You'll do

In this role you will be responsible for design and characterisation of formulations for the delivery of nucleic acids. This will involve working with advanced drug delivery platforms such as lipid nanoparticles. Working in close collaboration with peers in the advanced drug delivery group, you will continually be improving our end to end formulation design, characterisation and testing capabilities. As part of the team you will serve on global drug project teams working with scientists across UK, US and Sweden. You will also be expected to be part of and drive science networks and provide high quality scientific input across the organisation.

You will be involved in establishing and driving close research collaborations across academia and small biotech companies. We expect you to be an active member of the external scientific community enhancing our reputation as scientific leaders in the advanced drug delivery field.

We are seeking an ambitious scientist with a strong foundation in the delivery sciences and a specialisation in the formulation and analytical sciences as well as a great passion for experimental science. This is a hands-on, lab-based position where you will work with different teams, so you should like communicating and have the capacity to share your data.

If you are committed to developing your career in the pharmaceutical sciences - this might be the role for you!



Essential for the role

*

Master's degree in pharmaceutical sciences, biology, chemistry or a related discipline
*

Experience of formulating colloidal products such as lipid nanoparticles, polymeric delivery vehicles, other nanoparticle technologies, injectables or emulsions
*

Strong technical knowledge of nucleic-acid based drug delivery technologies
*

Experience in analytical instrumentations used in formulation characterization (particle size and zeta potential measurements, pKa determination etc.)
*

Strong record of scientific excellence evidenced by publications, patents and presentations
*

Thorough understanding of principles, applications and management of Safety Health and Environment (SHE)



Desirable for the role

*

PhD degree in pharmaceutical sciences, biology, chemistry or a related discipline
*

Practical skills for the design and synthesis and purification of new materials to support nucleic acid delivery efforts
*

Practical skills with cell based and in vivo assays to assess the performance of nanomedicines
*

Experience working with nanomedicines and experience formulating intracellular delivery systems for nucleotides and/or proteins
*

A working knowledge of CRISPR-related biology and a good knowledge of endosomal biology





Are you ready to make a difference? Send in your application, and we'll make it happen together.

For more information about the position please contact Director Ulrika Tehler, at [email protected]

We encourage you to send your application as soon as possible, but no later than May 22, 2022



Additional information

Our Gothenburg site: https://www.astrazeneca.com/our-science/gothenburg.html

Life in Gothenburg: https://www.movetogothenburg.com/

Culture and atmosphere of the Gothenburg site: https://www.linkedin.com/feed/update/urn:li:activity:6496327311678410752/ Visa mindre

Are you a scientist with expertise in, and passion for, the application of biophysical methods to study oligonucleotides and RNA? Would you like to apply this expertise to impact and expand the use of therapeutic oligonucleotides in drug projects as well as exploit new avenues in RNA-targeted drug discovery at AstraZeneca? Then this might be the next challenge for you!

AstraZeneca is committed to the development of next generation innovative medicines and is focused on expanding the use of oligonucleotides and molecular conjugates thereof, in the treatment of diseases across therapy areas. The company also exploits new avenues in RNA-targeted drug discovery to provide additional disease treatment opportunities. To help us with this, we are currently looking for a scientist with passion, expertise and experience to join our Mechanistic and Structural Biology Department (MSB) as a lab-based Associate Principal Scientist within the Biophysics group at AstraZeneca in Gothenburg, Sweden.

The MSB department has leading capabilities in biophysics, crystallography, cryo-EM, enzymology and cellular pharmacology. The Biophysics team has specific expertise in molecular biophysics methods, including SPR, NMR, ITC, DSF, HDX-MS, nMS and single molecule approaches. We apply biophysics across a range of different therapeutic modalities to support drug discovery from target validation to drug candidate. Welcome to join our exciting journey!

What you will do:
This laboratory-based role is for a leading Biophysicist in the Oligonucleotide/RNA area that wants to utilize the latest biophysical technologies. You will design and execute in vitro screening studies of Oligonucleotide interactions with proteins and RNA using suitable biophysical methods including but not limited to SPR and NMR. You will furthermore plan and conduct biophysical small-molecule screening activities to enable targeted delivery of Oligonucleotides by identifying and characterizing novel targeting moieties. In addition, you will be responsible for driving continuous learning and development of the biophysical capabilities to further augment our internal RNA-targeted drug discovery efforts by putting ideas into action. In the role you will also:

* Apply biophysical methods on isolated RNA target systems to develop a mechanistic understanding of oligonucleotide-mediated RNA degradation.
* Develop, implement and continuously improve biophysical screening methods focusing on the characterization of RNA, DNA and modified oligonucleotides, which may also include the characterization of small molecule binding to RNA.
* Analysis, interpretation and presentation of data to cross functional teams.
* Represent the Biophysics function at project interfaces and drive innovation, scientific excellence and external visibility of the Biophysics capability.

Essential for the role:

* PhD in biochemistry or biophysics (or equivalent education) with a strong understanding of protein and nucleic acid chemistry as well as RNA biology. Demonstrated experience working both independently and collaboratively in a laboratory environment, preferably in the Pharmaceutical or Biotechnology industry.
* Familiarity in the general application of biophysical methods for the study of molecular interactions. In-depth knowledge of the characterization of RNA and oligonucleotides by biophysical methods including practical knowledge in technologies like thermal unfolding/stability, surface plasmon resonance (BIAcore) and/or nuclear magnetic resonance (NMR)
* Proven expertise in performing assay development, validation and screening, including data analysis and the ability to communicate data interpretation clearly.
* Ability to manage multiple projects with clear understanding of project needs to ensure delivery of high-quality data with clear communication of timelines.

Finally, to be successful in this role we see that you have good social and communication skills, are collaborative and a strong team player. You should also be able to work independently and have a positive, goal oriented and problem-solving attitude.

Why AstraZeneca?
When we see an opportunity for change, we seize it and make it happen, because any opportunity can be the start of something big. Delivering life-changing medicines is about being entrepreneurial - finding those moments and recognizing their potential. Join us on our journey in finding new ways to work, pioneering cutting edge methods and bringing unexpected teams together!

If this sounds like your next challenge and place to work - apply today! We look forward to your application no later than 22nd May, 2022.

If you would like to know more about the position, the team or working at AstraZeneca, please reach out to hiring manager Stefan Geschwindner at [email protected].

Additional information:
Our Gothenburg site: https://www.astrazeneca.com/our-science/gothenburg.html
Life in Gothenburg: https://www.movetogothenburg.com/
Make a move to Global Gothenburg: https://www.youtube.com/watch?v=c-Iqbb4aw38
About BioPharmaceuticals R&D: https://www.astrazeneca.com/r-d.html Visa mindre

Could you provide the scientific leadership in Precision Medicine that enables a world-leading biopharmaceutical company to change the way healthcare is delivered to individual patients? At AstraZeneca, we're looking for Precision Medicine Experts - Director level to join our Precision Medicine and Biosamples department in Sweden.

Join a place built on innovation and creativity, where different views and perspectives are welcomed and valued. An environment that champions inclusion, and teams that reflect the diversity of the communities that we serve.

We're focused on providing medicines that make a real difference to patient care, and precision medicine is at the heart of our commitment to patient centric science and innovation. Using innovative diagnostic tests to evaluate individual responses to treatments, we aim to select appropriate and optimal therapies for patients who will benefit from them most. We apply precision medicine approaches across all therapy areas (TAs), and in over 85% of drug projects in our pipeline, which sets us apart from our competitors.

You'll be working alongside some of the brightest scientific talents in a vibrant, creative environment. With unrivalled facilities, you'll be able to immerse yourself in your work, advance your career and contribute towards scientific excellence. It's a place that inspires innovation and where research-led ideas are turned into new medicines that make a real difference in healthcare. As well as thriving in our multidisciplinary setting, you'll be able to work collaboratively with external diagnostic companies and world-class research institutes.

What you'll do
You'll be a member of the Biopharmaceutical Precision Medicine Unit aligned to our Biopharma therapeutic areas. Your objective will be to ensure that complementary & companion diagnostic tests, or equivalent patient segmentation tools, are delivered to drug projects. This will entail implementing the strategy agreed with early and late stage project teams and managing precision medicine activities comprising scientific & technical aspects of test development, test deployment into clinical trials, enabling regulatory & intellectual property strategies and financial tracking.

Providing expert advice on strategic precision medicine approaches and diagnostic development to product teams, you will be instrumental in ensuring that we adopt world-class practice in the field to increase the likelihood of successful drug launch and return on investment. You will explore and bring in new technologies to push the boundaries of diagnostics in and help to establish AstraZeneca as the world leading Precision Medicine Company.

Essential for the role

*

PhD or equivalent experience in a relevant subject
*

Experience in the development of complementary and companion diagnostic tests, or patient segmentation tools, and their implementation in clinical studies
*

Evidence of delivery and experience of precision medicine approaches & diagnostic development, ideally within, Respiratory and Immunology
*

Understanding of the regulatory environment for companion/complimentary diagnostics
*

A deep understanding of the principles of translational medicine and knowledge of Respiratory and Inflammatory diseases
*

Excellent skills in communication, stakeholder influencing, programme management
*

Significant understanding of the multidisciplinary functions involved in diagnostic development

Desirable for the role

*

Experience of developing diagnostic tests, regulatory interactions and test commercialisation
*

Experience in additional TAs (Cardiovascular, Renal and Metabolic diseases)
*

Record of publications and strong external reputation in the precision medicine field

This is an exciting opportunity for a talented Precision Medicine Expert to join a strong team at the forefront of precision medicine science, to innovate and support the portfolio of a major pharmaceutical company that has science at its heart and a strong pipeline whilst being based in the wonderful city of Gothenburg, Sweden.

Role can be considered at career levels E or F depending on the experience and suitability of the successful candidate.

Why AstraZeneca?
At AstraZeneca when we see an opportunity for change, we seize it and make it happen, because any opportunity no matter how small, can be the start of something big. Delivering life-changing medicines is about being entrepreneurial - finding those moments and recognising their potential. Join us on our journey of building a new kind of organisation to reset expectations of what a bio-pharmaceutical company can be. This means we're opening new ways to work, pioneering cutting edge methods and bringing unexpected teams together. Interested? Come and join our journey.

So, what's next?
Are you already imagining yourself joining our team? Good, because we can't wait to hear from you. We will go through the applications continuously so please apply as soon as possible but no later than April 15, 2022.

If you are interested, please apply now! Visa mindre

Are you a scientist with expertise in, and passion for, the application of biophysical methods to study oligonucleotides and RNA? Would you like to apply this expertise to impact and expand the use of therapeutic oligonucleotides in drug projects as well as exploit new avenues in RNA-targeted drug discovery at AstraZeneca? Then this might be the next challenge for you!

AstraZeneca is committed to the development of next generation innovative medicines and is focused on expanding the use of oligonucleotides and molecular conjugates thereof, in the treatment of diseases across therapy areas. The company also exploits new avenues in RNA-targeted drug discovery to provide additional disease treatment opportunities. To help us with this, we are currently looking for a scientist with passion, expertise and experience to join our Mechanistic and Structural Biology Department (MSB) as a lab-based Associate Principal Scientist within the Biophysics group at AstraZeneca in Gothenburg, Sweden.

The MSB department has leading capabilities in biophysics, crystallography, cryo-EM, enzymology and cellular pharmacology. The Biophysics team has specific expertise in molecular biophysics methods, including SPR, NMR, ITC, DSF, HDX-MS, nMS and single molecule approaches. We apply biophysics across a range of different therapeutic modalities to support drug discovery from target validation to drug candidate. Welcome to join our exciting journey!

What you will do:
This laboratory-based role is for a leading Biophysicist in the Oligonucleotide/RNA area that wants to utilize the latest biophysical technologies. You will design and execute in vitro screening studies of Oligonucleotide interactions with proteins and RNA using suitable biophysical methods including but not limited to SPR and NMR. You will furthermore plan and conduct biophysical small-molecule screening activities to enable targeted delivery of Oligonucleotides by identifying and characterizing novel targeting moieties. In addition, you will be responsible for driving continuous learning and development of the biophysical capabilities to further augment our internal RNA-targeted drug discovery efforts by putting ideas into action. In the role you will also:

* Apply biophysical methods on isolated RNA target systems to develop a mechanistic understanding of oligonucleotide-mediated RNA degradation.
* Develop, implement and continuously improve biophysical screening methods focusing on the characterization of RNA, DNA and modified oligonucleotides, which may also include the characterization of small molecule binding to RNA.
* Analysis, interpretation and presentation of data to cross functional teams.
* Represent the Biophysics function at project interfaces and drive innovation, scientific excellence and external visibility of the Biophysics capability.

Essential for the role:

* PhD in biochemistry or biophysics (or equivalent education) with a strong understanding of protein and nucleic acid chemistry as well as RNA biology. Demonstrated experience working both independently and collaboratively in a laboratory environment, preferably in the Pharmaceutical or Biotechnology industry.
* Familiarity in the general application of biophysical methods for the study of molecular interactions. In-depth knowledge of the characterization of RNA and oligonucleotides by biophysical methods including practical knowledge in technologies like thermal unfolding/stability, surface plasmon resonance (BIAcore) and/or nuclear magnetic resonance (NMR).
* Proven expertise in performing assay development, validation and screening, including data analysis and the ability to communicate data interpretation clearly.
* Ability to manage multiple projects with clear understanding of project needs to ensure delivery of high-quality data with clear communication of timelines.

Finally, to be successful in this role we see that you have good social and communication skills, are collaborative and a strong team player. You should also be able to work independently and have a positive, goal oriented and problem-solving attitude.

Why AstraZeneca?
When we see an opportunity for change, we seize it and make it happen, because any opportunity can be the start of something big. Delivering life-changing medicines is about being entrepreneurial - finding those moments and recognizing their potential. Join us on our journey in finding new ways to work, pioneering cutting edge methods and bringing unexpected teams together!

If this sounds like your next challenge and place to work - apply today! We look forward to your application no later than 1st of May, 2022.

If you would like to know more about the position, the team or working at AstraZeneca, please reach out to hiring manager Stefan Geschwindner at [email protected].

Additional information:
Our Gothenburg site: https://www.astrazeneca.com/our-science/gothenburg.html
Life in Gothenburg: https://www.movetogothenburg.com/
Make a move to Global Gothenburg: https://www.youtube.com/watch?v=c-Iqbb4aw38
About BioPharmaceuticals R&D: https://www.astrazeneca.com/r-d.html Visa mindre

Tillsammans skapar vi på Sahlgrenska Universitetssjukhuset vård av högsta kvalitet med patienten i fokus. Med stort engagemang och ständigt lärande är vi ett av landets ledande universitetssjukhus. Vi bedriver allt från länssjukvård till nationell högspecialiserad vård. Genom intressant forskning har vi en inriktning mot framtidens sjukvård. Hos oss är det viktigt med digital kompetens och att alla bidrar till den digitala utvecklingen. I vårt arbete tar vi tillvara den bredd av kunskap och erfarenhet vi gemensamt har – Tillsammans med dig vill vi skapa värde för våra patienter.

Regional laboratoriemedicin består av de laboratoriemedicinska verksamheterna på Södra Älvsborgs sjukhus, Sahlgrenska Universitetssjukhuset, Sjukhusen i väster och i NU-sjukvården. Organisationen tillhör Område 4 på Sahlgrenska Universitetssjukhuset. Organiseringen av laboratoriemedicin är ny från 1 januari 2021 och uppdraget är att skapa jämlik och effektiv vård för alla patienter i hela Västra Götalandsregionen.



Om verksamheten 

Till enheten Neurokemi Mölndal och Neurokemiska studier söker vi en erfaren Naturvetare som har dokumenterad erfarenhet att arbeta kvalitetssäkert med hög noggrannhet.

Enheten Neurokemi erbjuder en stimulerande arbetsmiljö med goda utvecklingsmöjligheter. Inom verksamheten bedrivs klinisk rutinverksamhet, läkemedels- och akademiska-studier samt en livlig forskning. Laboratoriet är miljöcertifierat och ackrediterat och stor vikt läggs vid kvalitetsarbete samt utveckling av vår verksamhet. Verksamheten bedrivs i nära samarbete med forskningsverksamheten och personer anställda av Göteborgs Universitet. Totalt arbetar cirka 85 personer i Neurokemis lokaler. 

Arbetsuppgifter

Du kommer framför allt att arbeta med analyser av olika markörer för Alzheimers sjukdom och andra degenerativa hjärnsjukdomar. Arbetet innefattar analysarbete av studieprover. Analyserna kan vara både automatiserade och manuella och sker på toppmodern utrustning. Validering av nya metoder och instrument kan förekomma. Vi arbetar huvudsakligen med likvorprover men utför även analyser i serum/plasma. För arbetsuppgifterna krävs god samarbetsförmåga samt kunskaper och erfarenhet av immunbaserade metoder. Vana av likvoranalyser, erfarenhet av laborativt arbete på sjukhuslaboratorium samt hantering av Cobas och Simoa instrument.

Om dig

Vi söker dig som har en magister/master med goda biokemiska kunskaper. Ett krav är minst två års laborativ erfarenhet. En förutsättning är att du kan uttrycka dig tydligt i tal och skrift på svenska och engelska samt hantera Officepaketet.

Kunskaper i GCLP (Good Clinical Laboratory Practice) och ultrasensitiva metoder är meriterande. Handhavande av manuell ELISA, samt analysering i likvor är också meriterande. 

Arbetet kräver god interaktions- och kommunikationsförmåga samt att du är noggrann och metodisk. Vi bedömer att det är av betydande vikt att du är flexibel och serviceinriktad samt har väl utvecklad social kompetens. Vi söker en person med ett engagerat positivt arbetssätt och stor vikt fästes vid personlig lämplighet.

Intervjuer kommer att ske löpande under ansökningstiden. 

Välkommen med din ansökan! 

Om Västra Götalandsregionen
Västra Götalandsregionen finns till för människorna i Västra Götaland. Vi ser till att det finns god hälso- och sjukvård för alla. Vi arbetar för en hållbar utveckling och tillväxt, bra miljö, förbättrad folkhälsa, ett rikt kulturliv och goda kommunikationer i hela Västra Götaland.
Västra Götalandsregionen arbetar aktivt för att digitalisera fler arbetssätt. För att vara en del av den digitala omvandlingen har du med dig grundläggande färdigheter och kan använda digitala verktyg och tjänster. Du kan söka information, kommunicera, interagera digitalt, är riskmedveten och har motivation att delta i utvecklingen för att lära nytt.


Vill du veta mer om Västra Götalandsregionen kan du besöka vår introduktion till nya medarbetare på länken https://www.vgregion.se/introduktion


Ansökan
Västra Götalandsregionen ser helst att du registrerar din ansökan via rekryteringssystemet. Om du som sökande har frågor om den utannonserade tjänsten eller av särskilda och speciella skäl inte kan registrera dina uppgifter i ett offentligt system - kontakta kontaktperson för respektive annons.


Till bemannings-, förmedlings- och rekryteringsföretag och till dig som är försäljare:
Vi undanber oss vänligen men bestämt direktkontakt med bemannings-, förmedlings- och rekryteringsföretag samt andra externa aktörer och försäljare av ytterligare jobbannonser. Västra Götalandsregionen har upphandlade avtal. Visa mindre

Could you provide the scientific leadership in Precision Medicine that enables a world-leading biopharmaceutical company to change the way healthcare is delivered to individual patients? At AstraZeneca, we're looking for Precision Medicine Experts - Director level to join our Precision Medicine and Biosamples department in Sweden.

Join a place built on innovation and creativity, where different views and perspectives are welcomed and valued. An environment that champions inclusion, and teams that reflect the diversity of the communities that we serve.

We're focused on providing medicines that make a real difference to patient care, and precision medicine is at the heart of our commitment to patient centric science and innovation. Using innovative diagnostic tests to evaluate individual responses to treatments, we aim to select appropriate and optimal therapies for patients who will benefit from them most. We apply precision medicine approaches across all therapy areas (TAs), and in over 85% of drug projects in our pipeline, which sets us apart from our competitors.

You'll be working alongside some of the brightest scientific talents in a vibrant, creative environment. With unrivalled facilities, you'll be able to immerse yourself in your work, advance your career and contribute towards scientific excellence. It's a place that inspires innovation and where research-led ideas are turned into new medicines that make a real difference in healthcare. As well as thriving in our multidisciplinary setting, you'll be able to work collaboratively with external diagnostic companies and world-class research institutes.

What you'll do
You'll be a member of the Biopharmaceutical Precision Medicine Unit aligned to our Biopharma therapeutic areas. Your objective will be to ensure that complementary & companion diagnostic tests, or equivalent patient segmentation tools, are delivered to drug projects. This will entail implementing the strategy agreed with early and late stage project teams and managing precision medicine activities comprising scientific & technical aspects of test development, test deployment into clinical trials, enabling regulatory & intellectual property strategies and financial tracking.

Providing expert advice on strategic precision medicine approaches and diagnostic development to product teams, you will be instrumental in ensuring that we adopt world-class practice in the field to increase the likelihood of successful drug launch and return on investment. You will explore and bring in new technologies to push the boundaries of diagnostics in and help to establish AstraZeneca as the world leading Precision Medicine Company.

Essential for the role

*

PhD or equivalent experience in a relevant subject
*

Experience in the development of complementary and companion diagnostic tests, or patient segmentation tools, and their implementation in clinical studies
*

Evidence of delivery and experience of precision medicine approaches & diagnostic development, ideally within, Respiratory and Immunology
*

Understanding of the regulatory environment for companion/complimentary diagnostics
*

A deep understanding of the principles of translational medicine and knowledge of Respiratory and Inflammatory diseases
*

Excellent skills in communication, stakeholder influencing, programme management
*

Significant understanding of the multidisciplinary functions involved in diagnostic development

Desirable for the role

*

Experience of developing diagnostic tests, regulatory interactions and test commercialisation
*

Experience in additional TAs (Cardiovascular, Renal and Metabolic diseases)
*

Record of publications and strong external reputation in the precision medicine field

This is an exciting opportunity for a talented Precision Medicine Expert to join a strong team at the forefront of precision medicine science, to innovate and support the portfolio of a major pharmaceutical company that has science at its heart and a strong pipeline whilst being based in the wonderful city of Gothenburg, Sweden.

Why AstraZeneca?
At AstraZeneca when we see an opportunity for change, we seize it and make it happen, because any opportunity no matter how small, can be the start of something big. Delivering life-changing medicines is about being entrepreneurial - finding those moments and recognising their potential. Join us on our journey of building a new kind of organisation to reset expectations of what a bio-pharmaceutical company can be. This means we're opening new ways to work, pioneering cutting edge methods and bringing unexpected teams together. Interested? Come and join our journey.

So, what's next?
Are you already imagining yourself joining our team? Good, because we can't wait to hear from you. We will go through the applications continuously so please apply as soon as possible but no later than February 28th, 2022.

If you are interested, please apply now!

Where can I find out more?

Follow AstraZeneca on LinkedIn

https://www.linkedin.com/company/1603/

Follow AstraZeneca on Facebook https://www.facebook.com/astrazenecacareers/

Follow AstraZeneca on Instagram https://www.instagram.com/astrazeneca_careers/?hl=en Visa mindre

Göteborgs universitet möter samhällets utmaningar med mångsidig kunskap. 53 300 studenter och 6 500 medarbetare gör universitetet till en stor och inspirerande arbetsplats. Stark forskning och attraktiva utbildningar lockar forskare och studenter från hela världen. Med ny kunskap och nya perspektiv bidrar Göteborgs universitet till en bättre framtid.

Vid institutionen för kemi och molekylärbiologi bedrivs forskning och forskarutbildning inom ett brett område som sträcker sig hela vägen från atom- och molekylskala via celler till hela organismer.

Information om forskargruppen:

Westenhoffs forskargrupp, där den aktuella anställningen är placerad, har som mål att visualisera strukturdynamik av proteiner och kemiska reaktioner. Forskningen sker på gränsområdet mellan biologi, kemi och fysik. Utveckling av nya spektroskopiska och röntgenbaserade verktyg är ett viktigt mål i verksamheten.

Mer information om vår forskning finns på http://www.cmb.gu.se.

Arbetsuppgifter
Vi söker två doktorander inom Westenhoffs ERC projekt "MolStrucDyn". Projektens mål är att bestämma strukturella förändringar i fotosensorproteiner. Vi planerar att använda ultrakorta röntgenpulser från frielektronlaserkällor och kryoelektron -mikroskopi för att nå dessa mål.

Arbetsuppgifter kan omfatta:


• Planering, förberedelse och genomförande av röntgendiffraktionsexperiment vid XFEL källor
• Proteinproduktion och kristalloptimering
• Bestämning av strukturen
• Identifiering och publicering av resultaten
• Vetenskapligt samarbete inom och utanför gruppen
• Kommunikation av resultaten

Doktorandtjänsten är placerat på Göteborgs Universitet t.o.m. Maj 2023. Därefter förväntas doktoranden att flytta med Westenhoffs arbetsgrupp till Institutionen för kemi/BMC på Uppsala Universitet.

Utbildning på forskarnivå omfattar fyra års heltidsstudier och leder fram till en doktorsexamen. 
Den som är anställd som doktorand ska främst ägna sig åt sin forskarutbildning. En doktorand får dock i begränsad omfattning arbeta med utbildning, forskning och administration. Sådant arbete får, innan doktorsexamen avlagts, inte omfatta mer än 20 procent av full arbetstid.

Behörighet
För tillträde till utbildning på forskarnivå krävs grundläggande och i förekommande fall särskild behörighet.

Grundläggande behörighet till utbildning på forskarnivå har den som:

1. Avlagt examen på avancerad nivå, eller
2. Fullgjort kursfordringar om minst 240 högskolepoäng, varav minst 60 högskolepoäng på avancerad nivå, eller
3. På annat sätt inom eller utom landet förvärvat motsvarande kunskaper.

Särskild behörighet har den som har:


• Avlagt examen på avancerad nivå i relevant* naturvetenskapligt ämne, eller
• Fullgjort kursfordringar om minst 60 högskolepoäng på avancerad nivå i relevanta* naturvetenskapliga ämnen, eller
• På något annat sätt inom eller utom landet förvärvat i huvudsak motsvarande kunskaper relevanta för den planerade utbildningen.* Relevant för den planerade utbildningen på forskarnivå

För särskild behörighet krävs också att sökande behärskar engelska i tal och skrift på en godtagbar nivå. Som riktmärke gäller 550 poäng på TOEFL-test (eller 213 poäng på TOEFL-CBT, eller 79 poäng på TOEFL-iBT).

Bedömningsgrund
Urval bland sökande som uppfyller krav på grundläggande och särskild behörighet baseras på förmågan att tillgodogöra sig utbildningen på forskarnivå.

Som en konkurrenskraftig kandidat har du:


• Examen (Masters / eller motsvarande, se ovan för mer information)
• Dokumenterad forskningserfarenhet inom biokemi, strukturbiologi eller ett område som är relaterat till projektet.
• Beprövad förmåga att arbeta självständigt och resultatstyrt i ett forskningsprojekt
• Egenskaper som gör dig till en dynamisk lagspelare

 

Anställning
Efter antagning till utbildning på forskarnivå kommer du att bli anställd som doktorand. Bestämmelser för anställning som doktorand återfinns i förordning SFS 1993:100. Den första anställningen som doktorand får gälla högst ett år. Anställningen får förnyas med högst två år i taget. En person får vara anställd som doktorand under sammanlagt högst åtta år. Den sammanlagda anställningstiden får dock inte vara längre än vad som motsvarar utbildning på forskarnivå på heltid under fyra år.

Anställningsform: Tidsbegränsad anställning, 4 år

Omfattning: 100%

Placering: Institutionen för kemi och molekylärbiologi, Göteborg

Tillträde: Enligt överenskommelse

Doktorandtjänsten är placerat på Göteborgs Universitet t.o.m. Maj 2023. Därefter förväntas doktoranden att flytta med Westenhoffs arbetsgrupp till Institutionen för kemi/BMC på Uppsala Universitet.

Universitetet tillämpar lokalt avtal om lönesättning av doktorander.

Kontaktuppgifter för anställningen
Prof. Sebastian Westenhoff:

E-mail: [email protected]

Tele: 0046766183936 

Fackliga organisationer
Fackliga företrädare vid Göteborgs universitet hittar du här:
https://www.gu.se/om-universitetet/jobba-hos-oss/hjalp-for-sokande

Ansökan
Komplett ansökan innehåller i PDF-format:


• Personligt brev
• CV
• Bevis om examen på avancerad nivå eller fullgjorda kurser, se behörighetskrav ovan
• Bevis om slutförd kurs i Engelska 6 eller motsvarande (gymnasiebetyg eller motsvarande)
• Två referenser (namn, mailadress, telefonnummer, relation)

För sökande med utländsk examen
Om examen är från lärosäte utanför Sverige ä du skyldig att informera dig om vad som gäller för just det landet

https://www.universityadmissions.se/en/entry-requirements/english-language-requirements/#how-can-i-meet-the-requirement

Du ansöker om att bli antagen till forskarstudier via Göteborgs universitets rekryteringsportal. Du som sökande ansvarar för att ansökan är komplett i enlighet med annonsen och att den är universitetet tillhanda senast sista ansökningsdag.

Ansökan ska vara inkommen senast: 2022-02-18

 

 

 


Till bemannings- och rekryteringsföretag och till dig som är försäljare: Göteborgs universitet anlitar upphandlad annonsbyrå i samband med rekrytering av personal. Vi undanber oss vänligen men bestämt direktkontakt med bemannings- och rekryteringsföretag samt försäljare av jobbannonser. Visa mindre

Could you provide the scientific leadership in Precision Medicine that enables a world-leading biopharmaceutical company to change the way healthcare is delivered to individual patients? At AstraZeneca, we're looking for Precision Medicine Experts - Respiratory and Immunology, to join our Precision Medicine and Biosamples department in Sweden.

Join a place built on innovation and creativity, where different views and perspectives are welcomed and valued. An environment that champions inclusion, and teams that reflect the diversity of the communities that we serve.

We're focused on providing medicines that make a real difference to patient care, and precision medicine is at the heart of our commitment to patient centric science and innovation. Using innovative diagnostic tests to evaluate individual responses to treatments, we aim to select appropriate and optimal therapies for patients who will benefit from them most. We apply precision medicine approaches across all therapy areas (TAs), and in over 85% of drug projects in our pipeline, which sets us apart from our competitors.

You'll be working alongside some of the brightest scientific talents in a vibrant, creative environment. With unrivalled facilities, you'll be able to immerse yourself in your work, advance your career and contribute towards scientific excellence. It's a place that inspires innovation and where research-led ideas are turned into new medicines that make a real difference in healthcare. As well as thriving in our multidisciplinary setting, you'll be able to work collaboratively with external diagnostic companies and world-class research institutes.

What you'll do
You'll be a member of the Biopharmaceutical Precision Medicine Unit aligned to the Respiratory and Immunology (R&I) therapeutic area. Your objective will be to ensure that complementary & companion diagnostic tests, or equivalent patient segmentation tools, are delivered to drug projects. This will entail implementing the strategy agreed with early and late stage project teams and managing precision medicine activities comprising scientific & technical aspects of test development, test deployment into clinical trials, enabling regulatory & intellectual property strategies and financial tracking.

Providing expert advice on strategic precision medicine approaches and diagnostic development to product teams, you will be instrumental in ensuring that we adopt world-class practice in the field to increase the likelihood of successful drug launch and return on investment. You will explore and bring in new technologies to push the boundaries of diagnostics in R&I and help to establish AstraZeneca as the world leading R&I Precision Medicine Company.

Essential for the role

*

PhD or equivalent experience in a relevant subject
*

Experience in the development of complementary and companion diagnostic tests, or patient segmentation tools, and their implementation in clinical studies
*

Evidence of delivery and experience of precision medicine approaches & diagnostic development, ideally within, Respiratory and Immunology
*

Understanding of the regulatory environment for companion/complimentary diagnostics
*

A deep understanding of the principles of translational medicine and knowledge of Respiratory and Inflammatory diseases
*

Excellent skills in communication, stakeholder influencing, programme management
*

Significant understanding of the multidisciplinary functions involved in diagnostic development

Desirable for the role

*

Experience of developing diagnostic tests, regulatory interactions and test commercialisation
*

Experience in additional TAs (Cardiovascular, Renal and Metabolic diseases)
*

Record of publications and strong external reputation in the precision medicine field

This is an exciting opportunity for a talented Precision Medicine Expert to join a strong team at the forefront of precision medicine science, to innovate and support the portfolio of a major pharmaceutical company that has science at its heart and a strong pipeline whilst being based in the wonderful city of Gothenburg, Sweden.

Role can be considered at Associate Director or Director level depending on the experience and suitability of the successful candidate.

Why AstraZeneca?
At AstraZeneca when we see an opportunity for change, we seize it and make it happen, because any opportunity no matter how small, can be the start of something big. Delivering life-changing medicines is about being entrepreneurial - finding those moments and recognising their potential. Join us on our journey of building a new kind of organisation to reset expectations of what a bio-pharmaceutical company can be. This means we're opening new ways to work, pioneering cutting edge methods and bringing unexpected teams together. Interested? Come and join our journey.

So, what's next?
Are you already imagining yourself joining our team? Good, because we can't wait to hear from you. We will go through the applications continuously so please apply as soon as possible but no later than January 15th, 2022. Visa mindre